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Evaluation on pathology and treatment effect for patients with hip osteoarthritis using subject-specific musculoskeletal simulation

Research Project

Project/Area Number 16K10912
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionYokohama City University

Principal Investigator

Inaba Yutaka  横浜市立大学, 医学研究科, 教授 (40336574)

Co-Investigator(Kenkyū-buntansha) 田原 大輔  龍谷大学, 理工学部, 准教授 (20447907)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords筋活動解析 / 変形性股関節症 / 関節病学
Outline of Final Research Achievements

To predict muscle forces, a motion capture technique of gait and musculoskeletal simulation are useful. In this study, we obtained gait motion of patients having hip osteoarthritis. Then, we reflected muscle strength by measurement of muscle volume based on CT images of the patient to the model and demonstrated patient-specific prediction of muscle forces during the gait motion. As results, muscle force decreased due to the decrease of muscle strength around hip joint. Simultaneously, change in walking posture due to the change in muscle strength was suppressed by the increase of the lower extremity muscle forces. The results suggested potency of the patient-specific prediction of muscle forces by reflecting muscle strength of each muscle in a gait motion and to understand mechanism of change in distribution of acting forces in hip osteoarthritis.

Academic Significance and Societal Importance of the Research Achievements

本研究により、股関節症患者の股関節周囲筋活動の特徴が明らかとなった。股関節周囲筋力が股関節症の進行や手術後の成績に及ぼす影響を調査することにより、股関節症の進行予防に対する筋力強化の効果や、治療効果を客観的に判定することが可能となると考える。
股関節症患者数は現在、国内で120~420万人と推定され、高齢化社会に伴って増加することを考えると、本研究で得られる成果の社会還元が大きく期待され、社会貢献度が高い。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (2 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] CT-based analysis of muscle volume and degeneration of gluteus medius in patients with unilateral hip osteoarthritis2017

    • Author(s)
      Momose Takako、Inaba Yutaka、Choe Hyonmin、Kobayashi Naomi、Tezuka Taro、Saito Tomoyuki
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: 18 Issue: 1 Pages: 1-7

    • DOI

      10.1186/s12891-017-1828-2

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Subject-specific musculoskeletal simulation of osteoarthritis to estimate muscle forces around the hip during abnormal gait.2017

    • Author(s)
      Tawara D, Sawa H, Momose T, Oba M, Inaba Y
    • Organizer
      The 26th Congress of the International Society of Biomechanics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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