Perioperative treatment strategy by analyzing blood flow and energy loss using multiple imaging modality
| Project/Area Number |
16K10970
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Anesthesiology
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Ishii Maki 京都府立医科大学, 医学(系)研究科(研究院), 助教 (50457959)
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| Co-Investigator(Kenkyū-buntansha) |
佐和 貞治 京都府立医科大学, 医学(系)研究科(研究院), 教授 (10206013)
板谷 慶一 京都府立医科大学, 医学(系)研究科(研究院), 講師 (70458777)
沼田 智 京都府立医科大学, 医学(系)研究科(研究院), 助教 (80735689)
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| Project Period (FY) |
2016-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2018: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | シアストレス / vector flow mapping / エネルギー損失 / wall shear stress / kinetic energy / IVPD / 左室補助人工心臓 / Vector flow mapping / コンピュータシミュレーション / ４D MRI / 運動エネルギー / エネルギー効率 / 4D MRI / 周術期管理学 |
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| Outline of Final Research Achievements |
We established the methodology that wall shear stress on aortic valve and aortic root can be analyzed by epiaortic echo using vector flow mapping.
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| Academic Significance and Societal Importance of the Research Achievements |
様々な疾患でシアストレスの異常で大動脈弁や大動脈壁の変性やアテローム化が起こることが知られているが、老年性の石灰化などは大動脈側の組織に起こり、左室補助人工心臓埋め込み後の患者では左室側の組織に起こる。我々の開発した手法でシアストレスを解析することで、さらに詳細な原因検索とより良い治療方法を探ることができる可能性がある。
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Report
(5 results)
Research Products
(34 results)
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[Journal Article] A novel in vivo assessment of fluid dynamics on aortic valve leaflet using epi-aortic echocardiogram2020
Author(s)
Hayashi H, Akiyama K, Itatani K, Deroo S, Sanchez J, Ferrari G, Colombo PC, Takeda K, Wu IY, Kainuma A, Takayama H
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Journal Title
Echocardiography
Volume: 37
Issue: 2
Pages: 323-330
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Flow-dynamics assessment of mitral-valve surgery by intraoperative vector flow mapping2017
Author(s)
Akiyama K, Nakamura N, Itatani K, Naito Y, Kinoshita M, Shimizu M, Hamaoka S, Kato H, Yasumoto H, Nakajima Y, Mizobe T, Numata S, Yaku H, Sawa T.
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Journal Title
Int Cardiovasc Thorac Surg
Volume: in press
Issue: 6
Pages: 869-875
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Vector flow mapping analysis of left ventricular energetic performance in healthy adult volunteers2017
Author(s)
Akiyama K, Maeda S, Matsuyama T, Kainuma A, Ishii M, Naito Y, Kinoshita M, Hamaoka S, Kato H, Nakajima Y, Nakamura N, Itatani K, Sawa T
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Journal Title
BMC Cardiovascular Disorders
Volume: 17
Issue: 1
Pages: 21-21
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Vector flow mapping and impaired left ventricular flow by Alfieri stitch.2017
Author(s)
Akiyama K, Itatani K, Naito Y, Kinoshita M, Shimizu M, Hamaoka S, Yasumoto H, Kato H, Nakajima Y, Numata S, Yaku H, Sawa T.
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Journal Title
J Cardiothorac Vasc Anesth
Volume: in press
Issue: 1
Pages: 211-214
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] Mitral valve replacement impairs left ventricular blood flow2016
Author(s)
Akiyama K, Itatani K, Kinoshita M, Shimizu M, Hamaoka S, Kato H, Naito Y, Nakajima Y, Numata S, Mizobe T, Yaku H, Sawa T
Organizer
American College of Cardiology
Place of Presentation
Maccormic Place Chicago
Year and Date
2016-04-05
Related Report
Int'l Joint Research
