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Development of novel method for facial nerve palsy using TMS-PAS

Research Project

Project/Area Number 16K11188
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionNagoya City University

Principal Investigator

Myurakami Shingo  名古屋市立大学, 医薬学総合研究院(医学), 教授 (80157750)

Co-Investigator(Kenkyū-buntansha) 植木 美乃  名古屋市立大学, 医薬学総合研究院(医学), 教授 (40467478)
稲垣 彰  名古屋市立大学, 医薬学総合研究院(医学), 講師 (70405166)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords顔面神経麻痺 / TMS / リハビリテーション / 経頭蓋磁気刺激法 / 耳科学 / 機能的脳画像法 / 顔面麻痺
Outline of Final Research Achievements

Complete or severe facial nerve palsy can result in less active facial movement or complication such as synlinesis and contractures. We have developed a novel method for facial nerve palsy using the combination with TMS and PAS. Totally five patients were treated with TMS and PAS. Facial nerve scores and complications were compared with 17 patiehts of facial palsy with same degree who were treatment without TMS or PAS. A little improvement was observed, although we could not show any significant differeene.

Academic Significance and Societal Importance of the Research Achievements

高度に顔面神経が障害された症例で病的共同運動や拘縮が発症するが、拘縮に対してはマッサージが、共同運動に対してはバイオフィードバックを利用した治療法が推奨されている。しかしその治療効果は限定的であり、新たな治療法の開発が望まれている。今回経頭蓋的磁気刺激法と末梢神経刺激を組み合わせて新たな治療法の開発を試みた。顔面神経麻痺の改善を若干の認めたが、有意な改善を示すことはできなかった。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (3 results)

All 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results) (of which Invited: 1 results)

  • [Journal Article] An improved system for grading and treating tinnitus.2017

    • Author(s)
      Takahashi M, Kabaya K, Sekiya K, Matsuda F, Sekiya Y, Esaki S, Sato Y, Inagaki A, Murakami S.
    • Journal Title

      Auris Nasus Larynx

      Volume: 27 Issue: 4 Pages: 30808-8

    • DOI

      10.1016/j.anl.2017.11.012

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Postoperative Headache after Undergoing Acoustic Neuroma Surgery via the Retrosigmoid Approach2017

    • Author(s)
      Aihara N, Yamada H, Takahashi M, Inagaki A, Murakami S, Mase M.
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 57 Issue: 12 Pages: 634-640

    • DOI

      10.2176/nmc.oa.2017-0108

    • NAID

      130006250662

    • ISSN
      0470-8105, 1349-8029
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 顔面神経機能再建の進歩と将来2016

    • Author(s)
      稲垣 彰
    • Organizer
      第117回日本耳鼻咽喉科学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県、名古屋市)
    • Year and Date
      2016-05-18
    • Related Report
      2016 Research-status Report
    • Invited

URL: 

Published: 2016-04-21   Modified: 2021-02-19  

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