• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Practice algorithm of the REM-related sleep apnea

Research Project

Project/Area Number 16K11251
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionUniversity of Occupational and Environmental Health, Japan

Principal Investigator

Kitamura Tarkuo  産業医科大学, 医学部, 准教授 (60341509)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsレム関連睡眠時無呼吸 / 睡眠呼吸障害 / 睡眠時無呼吸症候群 / 閉塞性睡眠時無呼吸 / 個別化医療 / レム睡眠 / 睡眠外科
Outline of Final Research Achievements

The REM related obstructive sleep apnea (REM-OSA) is one of the subtypes to account for 10-36% of the whole obstructive sleep apnea (OSA) patients and is clinical condition that respiratory events concentrates during REM sleep. As a result of this study, (1) CPAP adherence was low in the REM-OSA group, moreover, improvement of daytime sleepiness was poor in the REM-OSA group. (2) Nasal surgery is more effective for REM_AHI than for NREM_AHI. Although nasal surgery alone does not have a consistent effect on SDB. Meanwhile, the pharynx extended surgery is more effective for NREM_AHI than for REM_AHI. (3) The elderly people 65 years or older showed a correlation between REM_AHI and nasal cavity resistance level, and a nasal cavity resistance level was significantly higher in REM_OSA of elderly people.

Academic Significance and Societal Importance of the Research Achievements

1)レム関連睡眠時無呼吸に対するCPAPの効果: CPAP治療開始後の90日間の解析で、レム関連睡眠呼吸障害群ではアドヒアランス(1夜あたりの使用時間が4時間以上の割合)、エプワース眠気尺度(ESS)の改善度が有意に低値であった。1)レム関連睡眠時無呼吸に対するCPAPの効果: CPAP治療開始後の90日間の解析で、レム関連睡眠呼吸障害群ではアドヒアランス(1夜あたりの使用時間が4時間以上の割合)、エプワース眠気尺度(ESS)の改善度が有意に低値であった。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (16 results)

All 2019 2018 2017 2016

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (12 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] リアルワールドの睡眠呼吸障害診断 実臨床に活かす睡眠検査前のSAS疑診テクニック(第7回) 鼻腔通気度2019

    • Author(s)
      北村拓朗 宮崎総一郎 赤池亮太 伊藤有紀 鈴木秀明
    • Journal Title

      睡眠医療

      Volume: 13 Pages: 205-210

    • NAID

      40021930931

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Non-REM sleep-disordered breathing affects performance on the psychomotor vigilance task2018

    • Author(s)
      Kitamura T, Miyazaki S, Kadotani H, Kanemura T, Sulaiman HB, Takeuchi S, Tabata T, Suzuki H
    • Journal Title

      Sleep and Breathings

      Volume: 印刷中 Issue: 2 Pages: 329-335

    • DOI

      10.1007/s11325-017-1553-y

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] シンポジウム3 「Precision medicine in sleep medicine and surgery」成人OSAにおいてCPAPは本当に第一選択なのか? 「Cons: CPAPは成人治療の第一選択ではない」2018

    • Author(s)
      北村拓朗、鈴木秀明
    • Journal Title

      口咽科

      Volume: 31 Pages: 27-31

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 睡眠呼吸障害と認知機能障害2017

    • Author(s)
      北村拓朗、鈴木秀明、宮崎総一郎
    • Journal Title

      口腔・咽頭科

      Volume: 印刷中

    • NAID

      130006827025

    • Related Report
      2016 Research-status Report
  • [Presentation] 鼻閉が睡眠および認知機能に与える影響2019

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明、Chol Shin
    • Organizer
      日本睡眠学会第44回定期学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 未就学児における閉塞性睡眠時無呼吸の有病率2019

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明
    • Organizer
      日本睡眠学会第44回定期学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Pathophysiology and management of REM-related OSA2019

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明
    • Organizer
      日本睡眠学会第44回定期学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Personalized medicineにおけるsleep surgeryの意義2019

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明
    • Organizer
      日本睡眠学会第44回定期学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] NASAL SURGERY AFFECTS SLEEP-DISORDERED BREATHING IN REM SLEEP2019

    • Author(s)
      Takuro Kitamura, Hideaki Suzuki
    • Organizer
      ISSS 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] OSA with daytime sleepiness affects performance on the PVT2018

    • Author(s)
      Takuro Kitamura
    • Organizer
      Homecare clinical forum 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 睡眠時無呼吸症候群の眠気と認知症2018

    • Author(s)
      北村拓朗、宮崎総一郎、Chol Shin
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] OSASにおいて耳鼻科手術はどこまで有効か?2018

    • Author(s)
      北村拓朗
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] OSAにおける日中の眠気と注意力低下の関連について2018

    • Author(s)
      北村拓朗、宮崎総一郎、鈴木秀明
    • Organizer
      第31回日本口腔・咽頭科学会学術講演会
    • Related Report
      2018 Research-status Report
  • [Presentation] 成人OSAにおいてCPAPは本当に第一選択なのか? 「Cons: CPAPは成人治療の第一選択ではない」2017

    • Author(s)
      北村拓朗、鈴木秀明
    • Organizer
      第30回 口腔咽頭科学会総会
    • Related Report
      2017 Research-status Report
  • [Presentation] 睡眠時無呼吸治療と認知症予防2017

    • Author(s)
      北村拓朗、鈴木秀明
    • Organizer
      第42回 日本睡眠学会総会
    • Related Report
      2017 Research-status Report
  • [Presentation] 「シンポジウム睡眠呼吸障害とその周辺領域のアップデート」 睡眠呼吸障害と認知機能障害2016

    • Author(s)
      北村拓朗
    • Organizer
      第29回日本口腔咽頭科学会総会
    • Place of Presentation
      松江テルサ(島根県松江市)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2021-02-19  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi