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Monocular and binocular stereo vision affected by eye diseases.

Research Project

Project/Area Number 16K11319
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Ophthalmology
Research InstitutionThe University of Tokyo

Principal Investigator

SAWAMURA HIROMASA  東京大学, 医学部附属病院, 講師 (70444081)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords立体視 / 神経科学
Outline of Final Research Achievements

Perceiving three-dimensional (3D) shapes involves computing spatial derivatives of depth, which can be derived from both monocular and binocular disparity cues. The processing of 3D shape from shading, texture, motion or binocular disparity overlaps in many regions of inferior temporal and parietal cortex, suggesting that the respective visual cues interact in the extraction of 3D shape. We assessed 3D shape perception in normal and strabismus subjects. Our results showed that strabismus subjects with reduced or no binocular stereopsis poorly perceived three-dimensional shapes, defined by the monocular cues of shading or texture. Binocular stereopsis is essential for fine perception of 3D shape, even when defined by monocular static cues. Interaction between these cues may occur in ventral occipito-temporal regions. Our findings demonstrate the perceptual benefit of binocular stereopsis in strabismus patients.

Academic Significance and Societal Importance of the Research Achievements

本研究では、近年確立された単眼立体視、両眼立体視を用いた三次元形態認知を神経心理学的に評価する手法を用いている。既にこの手法を用いて大脳変性疾患において単眼・両眼立体視の障害程度と脳萎縮(灰白質の減少量)の程度が関連していることを見出した研究が報告されている。本研究では眼科疾患の一つである斜視を対象に、単眼立体視を用いた三次元形態認知においても両眼立体視情報が重要な役割を担っていること、このような神経心理学的手法を応用することで、正常の生理学的見地のみならず、疾患の病態生理へのアプローチも可能であることが示され、学術的、社会的に重要な研究と考えられる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2018 2017 2016 Other

All Int'l Joint Research (10 results) Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Invited: 1 results)

  • [Int'l Joint Research] Department of Experimental Psychology/University of Oxford, Oxford(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Department of Brain and Cognition/KU Leuven(ベルギー)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Department of Psychology/The Ohio State University(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Department of Neuroscience/University of Parma(イタリア)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Department of Neuroscience/University of Parma(イタリア)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Department of Experimental Psychology/University of Oxford(英国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Department of Brain and Cognition/KU Leuven, Leuven(ベルギー)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Department of Psychology/The Ohio State University(米国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Department of Experimental Psychology,/University of Oxford(United Kingdom)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Department of Neuroscience,/University of Parma(Italy)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Anatomical and Functional Network in Visual Perception2018

    • Author(s)
      澤村 裕正
    • Journal Title

      Neuro-Ophthalmology Japan

      Volume: 35 Issue: 2 Pages: 159-166

    • DOI

      10.11476/shinkeiganka.35.159

    • NAID

      130007404059

    • ISSN
      0289-7024, 2188-2002
    • Year and Date
      2018-06-25
    • Related Report
      2018 Annual Research Report
  • [Journal Article] Binocular stereo acuity affects monocular three-dimensional shape perception in patients with strabismus2018

    • Author(s)
      Sawamura H, Gillebert CR, Todd JT, Orban GA.
    • Journal Title

      Br J Ophthalmol

      Volume: 102 Issue: 10 Pages: 1413

    • DOI

      10.1136/bjophthalmol-2017-311393

    • Related Report
      2018 Annual Research Report 2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cancer-associated Retinopathy Developing After 10 Years of Complete Breast Cancer Remission2018

    • Author(s)
      Igarashi Nozomi、Sawamura Hiromasa、Kaburaki Toshikatsu、Aihara Makoto
    • Journal Title

      Neuro-Ophthalmology

      Volume: 43 Issue: 1 Pages: 36

    • DOI

      10.1080/01658107.2018.1460761

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Case of Posterior Ischemic Optic Neuropathy due to Giant Cell Arteritis with Advanced Glaucoma2017

    • Author(s)
      新井 隆浩, 澤村 裕正, 庄田 宏文, 山本 一彦, 相原 一
    • Journal Title

      Neuro-Ophthalmology Japan

      Volume: 34 Issue: 1 Pages: 54-60

    • DOI

      10.11476/shinkeiganka.34.54

    • NAID

      130005520207

    • ISSN
      0289-7024, 2188-2002
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Amblyopia associated with congenital facial nerve paralysis2016

    • Author(s)
      Iwamura H, Kondo K, Sawamura H, Baba S, Yasuhara K, Yamasoba T.
    • Journal Title

      ORL J Otorhinolaryngol Relat Spec.

      Volume: 78 Issue: 2 Pages: 105

    • DOI

      10.1159/000444932

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Estimating the binocular visual field of glaucoma patients with an adjustment for ocular dominance2016

    • Author(s)
      Matsuura M, Hirasawa K, Yanagisawa M, Hirasawa H, Murata H, Sawamura H, Mayama C, Asaoka R.
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 57 Issue: 7 Pages: 3276

    • DOI

      10.1167/iovs.15-19024

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Anti-Collapsing Response-Mediating Protein-5 Antibody–Positive Paraneoplastic Perioptic Neuritis without Typical Neurological Symptoms2016

    • Author(s)
      Igarashi N, Sawamura H, Kaburaki T, Aihara M
    • Journal Title

      Neuroophthalmology

      Volume: 41 Issue: 1 Pages: 24

    • DOI

      10.1080/01658107.2016.1241283

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] ヘッドマウント視野計アイモ(解説)2016

    • Author(s)
      澤村裕正、相原一
    • Journal Title

      眼科

      Volume: 58 Pages: 869-878

    • Related Report
      2016 Research-status Report
  • [Presentation] 視覚認知のNetwork2017

    • Author(s)
      澤村 裕正
    • Organizer
      第55回日本神経眼科学会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 原因不明の乳頭浮腫に網膜動脈分枝閉塞症を続発した一例2017

    • Author(s)
      青山 祐里香、澤村 裕正、蕪城 俊克、若倉 雅登、相原 一
    • Organizer
      第55回日本神経眼科学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 原因不明の両側乳頭浮腫を来した症例2017

    • Author(s)
      浅野 祥太郎、澤村 裕正、山上 明子、相原 一
    • Organizer
      第55回日本神経眼科学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 斜視患者と健常者における立体知覚の認知差異2016

    • Author(s)
      澤村裕正
    • Organizer
      第120回 日本眼科学会総会
    • Place of Presentation
      仙台
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2022-02-22  

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