Molecularly targeted therapy and photo dynamic therapy for refractory lymphangioma
Project/Area Number |
16K11351
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Pediatric surgery
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Research Institution | Kyoto Prefectural University of Medicine |
Principal Investigator |
Fumino Shigehisa 京都府立医科大学, 医学(系)研究科(研究院), 助教 (40405254)
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Co-Investigator(Kenkyū-buntansha) |
東 真弓 京都府立医科大学, 医学(系)研究科(研究院), 助教 (10380453)
古川 泰三 京都府立医科大学, 医学(系)研究科(研究院), 講師 (20515291)
田尻 達郎 京都府立医科大学, 医学(系)研究科(研究院), 教授 (80304806)
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Project Period (FY) |
2016-04-01 – 2019-03-31
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Project Status |
Completed (Fiscal Year 2018)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | リンパ管腫 / 小児外科 |
Outline of Final Research Achievements |
This study was attempted to develop molecularly targeted therapy and photo dynamic therapy for refractory lymphangioma. Though, the technical difficulty was proved in the development of rat model. Finally, we attempted clinical application of mTOR inhibitor for patients with refractory lymphangioma. The results of this study is due to be released in near future.
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Academic Significance and Societal Importance of the Research Achievements |
現在特許出願および臨床研究の一環であるため,結果を公表することはできないが,本研究はリンパ管腫治療を大きく変える可能性がある.
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Report
(4 results)
Research Products
(35 results)
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[Journal Article] Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-transduction with MYCL and MYOD12017
Author(s)
Wakao J, Kishida T, Fumino S, Kimura K, Yamamoto K, Kotani SI, Mizushima K, Naito Y, Yoshikawa T, Tajiri T, Mazda O
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Journal Title
Biochemical and Biophysical Research Communications
Volume: 488
Issue: 2
Pages: 368-373
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] JNK-STAT3 pathway in neuroblastoma.2016
Author(s)
Higashi M, Sakai K, Fumino S, Aoi S, Furukawa T, Tajiri T
Organizer
40th World Congress of the International College of Surgeons
Place of Presentation
京都
Year and Date
2016-10-24
Related Report
Int'l Joint Research
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[Presentation] Tumor-homing effect of human mesenchymal stem cells in a TH-MYCN mouse model of neuroblastoma.2016
Author(s)
Kimura K, Kishida T, Wakao J, Tanaka T, Higashi M, Fumino S, Aoi S, Furukawa T, Mazda O, Tajiri T
Organizer
49th Annual Meeting of the Pacific Association of Pediatric Surgeons (PAPS)
Place of Presentation
Kauai,USA
Year and Date
2016-05-17
Related Report
Int'l Joint Research
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