| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Ischemic tolerance is attracting attention as an adaptation phenomenon of neurons to a non-lethal ischemic injury. We previously showed that non-lethal injury-induced neural stem cells developed within the ischemic areas. This research was studied for the purpose of analyzing about the pattern of endogenous neural stem cells and pericytes under ischemic tolerance.
As a result, nestin positive neural stem cell was observed by a cerebral cortex leptomeninx department around the microvessels in an infarct areas, and more expression of GFAP positive astrocytes was observed at a site distant from microvessels. Because this cell was a nestin positive cell, the thing by which a reactivity astrocyte has a possibility with the special qualities of the neural stem cell was suggested.
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