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Establishing new medical and dental health care systems through bidirectional cooperation between osteoporosis and rheumatoid arthritis and periodontal disease

Research Project

Project/Area Number 16K11875
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionAichi Gakuin University

Principal Investigator

SHIMAZAKI Yoshihiro  愛知学院大学, 歯学部, 教授 (10291519)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords骨粗鬆症 / 関節リウマチ / 歯周病 / 医科歯科連携 / 歯周疾患 / パノラマX線画像 / パノラマX線写真 / 歯学
Outline of Final Research Achievements

Among the community and institutional older people, those with fewer number of teeth had a significantly higher risk of osteoporosis. An analysis of the relationship between the mandibular cortical width (MCW) of panoramic X-ray images and the bone mineral density (BMD) showed a significant positive correlation between MCW and BMD. In the analysis of rheumatoid arthritis (RA) patients, there was no difference in oral hygiene habits depending on the severity of RA, but the higher the RA severity, the poorer the oral hygiene and periodontal conditions were.
Analyzed the data of the older people from the viewpoint of medical-dental cooperation, the older people with a small number of teeth and eating fast were at high risk of metabolic syndrome. In addition, it was found that the dental visits for periodontal treatment suppressed the risk of diabetes.

Academic Significance and Societal Importance of the Research Achievements

近年、口腔の健康と全身の健康の関連が注目されている。骨粗鬆症や関節リウマチなどの整形外科疾患は、口腔の健康との関連が報告されているが医科と歯科の連携は十分ではない。
本研究では、高齢者おける歯数と骨密度との関連および歯科で撮影するパノラマX線画像所見と骨密度との有意な関連を示した。また、関節リウマチ患者は口腔清掃習慣に関わらず、口腔清掃状態や歯周状態が悪いことが明らかとなった。これらの結果の学術的意義は、口腔と全身の健康の関連を新たな視点から分析し示している点にある。また、整形外科疾患を有する患者に対して医科歯科連携を深める必要性を示唆している点において社会的意義がある。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (24 results)

All 2020 2019 2018 2017 2016

All Journal Article (15 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 11 results,  Open Access: 3 results) Presentation (9 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Association between dental consultation and oral health status among male Japanese employees2020

    • Author(s)
      Shimazaki Yoshihiro, Tonoyama Toshiya, Miyano Yoshikazu, Miyata Yasushi, Hisada Kazuaki, Nagasawa Tsuneyasu
    • Journal Title

      Journal of Occupational Health

      Volume: 62 Issue: 1 Pages: n/a

    • DOI

      10.1002/1348-9585.12104

    • NAID

      130007803107

    • ISSN
      1341-9145, 1348-9585
    • Year and Date
      2020-01-20
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Number of Teeth, Oral Self-care, Eating Speed, and Metabolic Syndrome in an Aged Japanese Population2019

    • Author(s)
      Saito Mizuki, Shimazaki Yoshihiro, Nonoyama Toshiya, Tadokoro Yasushi
    • Journal Title

      Journal of Epidemiology

      Volume: 29 Issue: 1 Pages: 26-32

    • DOI

      10.2188/jea.JE20170210

    • NAID

      130007542913

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2019-01-05
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Associations of number of teeth with medical costs and hospitalization duration in an older Japanese population2019

    • Author(s)
      Saito Mizuki, Shimazaki Yoshihiro, Tonoyama Toshiya, Tadokoro Yasushi
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 19 Issue: 4 Pages: 335-341

    • DOI

      10.1111/ggi.13622

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 研究者の最新動向 骨粗鬆症スクリーニングへの歯科パノラマX線画像の応用2019

    • Author(s)
      嶋崎義浩,齋藤瑞季,有地榮一郎,勝又明敏
    • Journal Title

      Precision Medicine

      Volume: 2 (11) Pages: 1088-1090

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Risk factors for tooth loss in adult Japanese dental patients: 8020 Promotion Foundation Study2019

    • Author(s)
      Saito Mizuki, Shimazaki Yoshihiro, Kakuhiro Fukai, Michiko Furuta, Jun Aida, Yuichi Ando, Hiedo Miyazaki, Masai Kambara
    • Journal Title

      Journal of Investigative and Clinical Dentistry

      Volume: 10 Issue: 2

    • DOI

      10.1111/jicd.12392

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] 歯科パノラマX線画像による骨粗鬆症スクリーニング2018

    • Author(s)
      嶋﨑義浩, 有地榮一郎, 勝又明敏
    • Journal Title

      別冊Bio Clinica: 慢性炎症と疾患

      Volume: 7 (2) Pages: 134-136

    • Related Report
      2018 Research-status Report
  • [Journal Article] Influence of plaque control on the relationship between rheumatoid arthritis and periodontal health status among Japanese rheumatoid arthritis patients2018

    • Author(s)
      Hashimoto Hiroko, Hashimoto Simpei, Muto Akinori, Dewake Nanae, Shimazaki Yoshihiro
    • Journal Title

      Journal of Periodontology

      Volume: 89 Issue: 9 Pages: 1033-1042

    • DOI

      10.1002/jper.17-0575

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 歯科パノラマX線画像による骨粗鬆症スクリーニングの試み2018

    • Author(s)
      嶋﨑義浩, 有地榮一郎, 勝又明敏
    • Journal Title

      別冊Bio Clinica: 慢性炎症と疾患

      Volume: 7 (3) Pages: 107-109

    • Related Report
      2018 Research-status Report
  • [Journal Article] 後期高齢者における歯数と医療費との関連 三重県後期高齢者医療広域連合歯科健診の結果とレセプトデータから2018

    • Author(s)
      齋藤瑞季, 嶋﨑義浩, 野々山順也, 田所 泰
    • Journal Title

      厚生の指標

      Volume: 65 Pages: 8-13

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Type of dental visit and number of remaining teeth in Japanese elders2018

    • Author(s)
      Saito Mizuki, Shimazaki Yoshihiro, Nonoyama Toshiya, Tadokoro Yasushi
    • Journal Title

      Journal of Oral Science

      Volume: 60 Issue: 4 Pages: 611-617

    • DOI

      10.2334/josnusd.17-0335

    • NAID

      130007552974

    • ISSN
      1343-4934, 1880-4926
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between type of dental visit and number of remaining teeth in Japanese elderly population2018

    • Author(s)
      Saito Mizuki、Shimazaki Yoshihiro、Nonoyama Toshiya、Tadokoro Yasushi
    • Journal Title

      Journal of Oral Science

      Volume: -

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Number of Teeth, Oral Self-care, Eating Speed, and Metabolic Syndrome in an Aged Japanese Population2018

    • Author(s)
      Saito Mizuki、Shimazaki Yoshihiro、Nonoyama Toshiya、Tadokoro Yasushi
    • Journal Title

      Journal of Epidemiology

      Volume: -

    • NAID

      130007542913

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 歯科パノラマX線画像による骨粗鬆症スクリーニング2017

    • Author(s)
      嶋﨑義浩,有地榮一郎,勝又明敏
    • Journal Title

      Medical Science Digest

      Volume: 43 Pages: 435-436

    • Related Report
      2017 Research-status Report
  • [Journal Article] Association between dental visits for periodontal treatment and type 2 diabetes mellitus in an elderly Japanese cohort2017

    • Author(s)
      Saito Mizuki、Shimazaki Yoshihiro、Nonoyama Toshiya、Tadokoro Yasushi
    • Journal Title

      Journal of Clinical Periodontology

      Volume: 44 Issue: 11 Pages: 1133-1139

    • DOI

      10.1111/jcpe.12804

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Bone mineral density and tooth number among elderly women in Japan2017

    • Author(s)
      Hashimoto Hiroko, Dewake Nanae, Muto Akinori, Nonoyama Toshiya, Shimazaki Yoshihiro
    • Journal Title

      Aichi Gakuin Dental Science

      Volume: 30 Pages: 21-27

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 関節リウマチ患者の歯周状態とRA重症度との関連2019

    • Author(s)
      橋本周子,武藤昭紀,出分菜々衣,橋本晋平,嶋崎義浩
    • Organizer
      第68会日本口腔衛生学会・総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Effect of continuous dental visits on oral health maintenance2019

    • Author(s)
      Shimazaki Yoshihiro, Sasaki Akihiro, Hayashi Ryosuke, Mori Yasushi, Nakashima Seiji, Machino Atsushi, Abe Yoshikazu
    • Organizer
      4th IADR Asia Pacific Region
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 歯科受診患者における歯の喪失に関わる要因についての検討2018

    • Author(s)
      齋藤瑞季, 嶋﨑義浩, 深井穫博, 古田美智子, 相田 潤, 安藤雄一, 宮﨑秀夫, 神原正樹
    • Organizer
      第67回日本口腔衛生学会・総会
    • Related Report
      2018 Research-status Report
  • [Presentation] Relationship between mandibular cortical width and bone mineral density2018

    • Author(s)
      Shimazaki Yoshihiro, Saito Mizuki, Katsumata Akitoshi, Ariji Eiichiro, Yoshii Saori, Takeyama Hideo
    • Organizer
      96th General Session & Exhibition of the IADR
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] ビッグデータ解析からみえる健康寿命延伸に向けた課題2018

    • Author(s)
      嶋﨑義浩
    • Organizer
      第149回日本歯科保存学会2018年度秋期学術大会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 関節リウマチ患者の口腔健康状態についての検討2017

    • Author(s)
      橋本周子, 橋本晋平, 武藤昭紀, 出分菜々衣, 嶋﨑義浩
    • Organizer
      第60回東海口腔衛生学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 後期高齢者における歯科受診状況と歯の喪失との関連2017

    • Author(s)
      齋藤瑞季, 嶋﨑義浩, 野々山順也, 田所 泰
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Research-status Report
  • [Presentation] Bone density and the number of teeth in elderly women2017

    • Author(s)
      Hiroko Hashimoto, Nanae Dewake, Akinori Muto, Toshiya Nonoyama, Yoshihiro Shimazaki
    • Organizer
      95th General Session & Exhibition of the IADR
    • Place of Presentation
      Moscone West Building (San Francisco, USA)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 関節リウマチ患者の口腔健康状態についての検討2016

    • Author(s)
      橋本周子、武藤昭紀、出分菜々衣、橋本晋平、嶋崎義浩
    • Organizer
      第65回日本口腔衛生学会・総会
    • Place of Presentation
      東京医科歯科大学(東京、お茶の水)
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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