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Is it possible to stop the general frailty by early detection and early improvement of ora frailty?

Research Project

Project/Area Number 16K11887
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionHiroshima University

Principal Investigator

YOSHIKAWA MINEKA  広島大学, 医系科学研究科(歯), 准教授 (00444688)

Co-Investigator(Kenkyū-buntansha) 栢下 淳  県立広島大学, 人間文化学部, 教授 (40312178)
津賀 一弘  広島大学, 医系科学研究科(歯), 教授 (60217289)
木村 浩彰  広島大学, 病院(医), 教授 (60363074)
吉田 光由  広島大学, 医系科学研究科(歯), 准教授 (50284211)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsオーラルフレイル / サルコペニア / 高齢者 / 舌圧 / 栄養 / 口腔機能 / 口腔機能低下症 / フレイル / 老化 / フレイルティ / 歯学 / リハビリテーション
Outline of Final Research Achievements

48 elderly people (28 women, 67-91 years old) who live independently joined. Questionnaire surveys and surveys on oral and systemic functions were conducted. The collaborators were divided into 19 control groups, 11 oral rehabilitation groups, and 13 nutritional groups. The oral rehabilitation group and nutritional group were received the guidance of 8 weeks oral rehabilitation (tongue resistance training) or nutritional guidance by a registered dietitian. We provided nutritional guidance and conducted a 18 months follow-up study. From the results of the initial survey, a significant correlation was found between grip strength and tongue pressure, and grip strength and knee extension strength in women (P <0.01). In the oral rehabilitation group and the nutritional guidance group who had the intervention, the numerical value was improved during the intervention period, but after the intervention, the tendency was gradually returned to the initial state or deteriorated.

Academic Significance and Societal Importance of the Research Achievements

本研究開始後,「口腔機能低下症」が検査に基づく疾患名として認められ,近年ではフレイル予防対策の普及も伴い,口腔健康の維持・増進の意識も高まりつつある.本結果では,口腔機能低下症の診断基準の1つである舌圧へ着目し,8週間集中的に舌抵抗訓練をすることで,舌圧は即時に改善を認め,訓練終了後も半年間は維持できることが明らかとなった.専門家による適切なアドバイスに基づき,高齢者自らが口腔健康の維持増進を目標として口腔リハビリテーションを継続,もしくは一定間隔で短期集中的なリハビリテーションを繰り返すことで,口腔機能低下症を予防できる可能性が示された.

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (9 results)

All 2019 2018 2017 2016

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Int'l Joint Research: 4 results) Book (2 results)

  • [Journal Article] Maximum tongue pressure is associated with swallowing dysfunction in ALS patients2017

    • Author(s)
      Aya Hiraoka, Mineka Yoshikawa, Masahiro Nakamori, Naohisa Hosomi, Toshikazu Nagasaki, Takahiro Mori, Masaya Oda, Hirofumi Maruyama, Mitsuyoshi Yoshida, Yuishin Izumi, Masayasu Matsumoto, Kazuhiro Tsuga
    • Journal Title

      Dysphagia

      Volume: 印刷中 Issue: 4 Pages: 542-547

    • DOI

      10.1007/s00455-017-9797-z

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a candy-sucking test for evaluating oral function in elderly patients with dementia: A pilot study.2017

    • Author(s)
      Mori T, Yoshikawa M, Maruyama M, Hiraoka A, Nakamori M, Yoshida M, Tsuga K
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 印刷中 Issue: 11 Pages: 1977-1981

    • DOI

      10.1111/ggi.13003

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Prediction of pneumonia in acute stroke patients using tongue pressure measurements2016

    • Author(s)
      Masahiro Nakamori, Naohisa Hosomi, Kenichi Ishikawa, Eiji Imamura, Takeo Shishido, Tomohiko Ohshita, Mineka Yoshikawa, Kazuhiro Tsuga, Shinichi Wakabayashi, Hirofumi Maruyama, Masayasu Matsumoto
    • Journal Title

      PLOS ONE

      Volume: 11 Issue: 11 Pages: e0165837-e0165837

    • DOI

      10.1371/journal.pone.0165837

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Tongue-pressure training in Japanese healthy elderly: Training and detraining effects in longitudinal RCT study2019

    • Author(s)
      Yoshikawa -Sonoda M, Kitagawa M, Nagao A, Nishikawa Y, Yoshida M, Tsuga K
    • Organizer
      9th ESSD Congress
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between sarcopenia, EAT-10, and tongue pressure in Japanese elderly2018

    • Author(s)
      M. YOSHIKAWA-SONODA
    • Organizer
      8th ESSD Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Relationship between eating posture and maximum tongue pressure in healthy young and dependent elderly people2016

    • Author(s)
      Yoshikawa M, Nagakawa K, Tanaka R, Shimada R, Hiraoak A, Mori T, Tsuga K
    • Organizer
      Congress of European Society for Swallowing disorders
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2016-10-12
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Relationship between eating posture and maximum tongue pressure2016

    • Author(s)
      Yoshikawa M, Mori T, Tsuga K
    • Organizer
      94th generak sessiong and exhibition of the IADR
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-06-22
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Book] 新よくわかる顎口腔機能 舌圧測定2017

    • Author(s)
      吉川峰加,小野高裕,津賀一弘
    • Total Pages
      304
    • Publisher
      医歯薬出版株式会社
    • Related Report
      2016 Research-status Report
  • [Book] 嚥下機能の現状評価~摂食嚥下障害患者を地域で見守るために知っておいてもらいたいこと―「嚥下パスポート」を有効に利用していくために―2016

    • Author(s)
      細見直永,栢下淳編,青木志郎,上野弘貴,栢下淳,川端直子,長尾晶子,平山順子,細見直永,益田慎,水戸裕香,山縣誉志江,吉川峰加,吉田光由,渡邉光子
    • Total Pages
      50
    • Publisher
      県立広島大学人間文化学部健康科学科
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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