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Enhancement of autonomic nervous control function for orofacial pain

Research Project

Project/Area Number 16K11888
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

MOMOTA Yukihiro  徳島大学, 大学院医歯薬学研究部(歯学域), 講師 (00304543)

Co-Investigator(Kenkyū-buntansha) 東 雅之  徳島大学, 大学院医歯薬学研究部(歯学域), 教授 (20144983)
高野 栄之  徳島大学, 病院, 特任助教 (30380091)
可児 耕一  徳島大学, 病院, 助教 (60709583)
富岡 重正  徳島文理大学, 保健福祉学部, 教授 (70188770)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords歯科心身医学
Outline of Final Research Achievements

In the course of treatment of orofacial pain, they realized that the autonomic nervous system was susceptible to degeneration, and thought that strengthening the regulatory function of the autonomic nerve would improve the treatment result. We came up with the idea of making the most of self-care by patients themselves, and focused on the heart rate variability biofeedback method (hereinafter HRV-BF). HRV-BF is non-invasive and simple, and can be continuously performed because it does not involve labor. Furthermore, HRV-BF, like SGR, is thought to act on the regulatory function of autonomic nerves, and is extremely promising as a complement or alternative treatment for SGR. Moreover, detailed pathological analysis in the course of treatment of orofacial pain was performed by HRV analysis using D parameter which is a novel therapeutic marker.

Academic Significance and Societal Importance of the Research Achievements

本研究の意義は、1)口腔顔面痛の治療成績の向上に貢献することである。口腔顔面痛患者のQOLは著しく低下しており、患者・社会からの口腔顔面痛に関する研究・医療の発展を望む声は大きい。
次に、2)口腔顔面痛の治療過程における病態の解明に貢献することである。口腔顔面痛の病態解析は有効な手法が存在しない。したがって、本研究によって得られる知見は口腔顔面痛に関する研究・医療に新たな視座を与え、その発展のための大きな推進力となろう。また、疼痛治療をセルフケア主体とする試みは医療財政への負担を軽減し、医療経済上も有益である。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (7 results)

All 2019 2018 2016

All Journal Article (7 results) (of which Peer Reviewed: 6 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] A Case of Well-Managed Sarcoidosis with Cardiac Autonomic Dysfunction during Dental Therapy: Significance of Heart Rate Variability Analysis.2019

    • Author(s)
      Momota Y, Masuda N, Takano H, Azuma M
    • Journal Title

      IOSR Journal of Dental and Medical Sciences

      Volume: 18 Pages: 27-29

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oral Lichen Planus Well-Treated with Kampo Medicines2019

    • Author(s)
      Momota Y, Takano H, Kani K, Ono S, Azuma M
    • Journal Title

      IOSR Journal of Dental and Medical Sciences

      Volume: 18 Pages: 68-72

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Overview of Kampo Medicine in Dentistry:Effectiveness of Kampo Medicines against Intractable Diseases2018

    • Author(s)
      桃田 幸弘、東 雅之、小林 真之
    • Journal Title

      ORAL THERAPEUTICS AND PHARMACOLOGY

      Volume: 37 Issue: 3 Pages: 129-133

    • DOI

      10.11263/jsotp.3008

    • NAID

      130007593226

    • ISSN
      0288-1012, 1884-4928
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recurrent Aphthous Stomatitis Well-Treated with Inchinkoto: Two Case Reports.2018

    • Author(s)
      Momota Y, Takano H, Kani K, Miyamoto Y, Azuma M.
    • Journal Title

      IOSR Journal of Dental and Medical Sciences

      Volume: 17 Pages: 6-11

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Case of Well-Managed Fibromyalgia with Autonomic Dysfunction during Dental Therapy: Significance of Heart Rate Variability Analysis.2018

    • Author(s)
      Momota Y, Kani K, Masuda N, Eguchi S, Otsuka R, Takano H, Azuma M.
    • Journal Title

      IOSR Journal of Dental and Medical Sciences

      Volume: 17 Pages: 33-35

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 舌痛症の診断を再考する2018

    • Author(s)
      桃田幸弘,高野栄之,東 雅之
    • Journal Title

      徳島大 大学開放実践センター紀要

      Volume: 27 Pages: 41-46

    • NAID

      120006530179

    • Related Report
      2017 Research-status Report
  • [Journal Article] Significance of Time-Domain Measurements of Heart Rate Variability in Burning Mouth Syndrome.2016

    • Author(s)
      Momota Y, Takano H, Kani K, Matsumoto F, Aota K, Yamanoi T, Kondo C, Takase N, Miyamoto Y, Tomioka S, Azuma M.
    • Journal Title

      IOSR J Dent Med Sci

      Volume: 15 (1) Pages: 25-33

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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