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Research on correspondence to dysphagia of Alzheimer's disease and Lewy body dementia.

Research Project

Project/Area Number 16K11907
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

Hirano Hirohiko  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (10271561)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords認知症 / アルツハイマー病 / レビー小体型認知症 / 摂食嚥下障害
Outline of Final Research Achievements

There was still not enough to assess and manage dysphagia due to degenerative dementia. Therefore, this study focused on Alzheimer's disease (AD) and Lewy-Body dementia, and aimed at conducting a comprehensive examination of dysphagia and examining its correspondence.
As a result of this study, it was clarified that there is a difference in the stage of the expression of dysfunction of gargling, rinsing and brush teeth as AD progresses. In addition, the refusal of oral health care was related to a predictive factor in AD with a decline in swallowing function one year later, suggesting a link between the appearance of behavioral and psychological symptom of dementia and the decline in swallowing function.
From the above, it was inferred that oral function management such as swallowing function is important to contents based on the care in elderly people with dementia and to properly instruction to carers.

Academic Significance and Societal Importance of the Research Achievements

認知症施策推進総合戦略の中で「認知症の容態に応じた適時・適切な医療・介護等の提供」が掲げられているが、認知症高齢者に対する標準化した指針の提示やそれに資する知見が不十分という課題があり、認知症高齢者への標準的な口腔衛生管理および摂食嚥下機能管理の広がりは遅れている。以上の社会的背景の一助となるよう認知症と摂食嚥下機能に関する検討を行った結果、認知症重症度により口腔機能障害の出現段階の違いや、嚥下機能低下に関する予知因子を明らかにした。
本研究成果に関しては、積極的に学会や誌上発表を行うとともに、歯科専門職や施設等の介護職員に対して講演等を行い、広く発信することに努めた。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (15 results)

All 2019 2018 2017 2016

All Journal Article (8 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 5 results,  Open Access: 2 results) Presentation (7 results) (of which Int'l Joint Research: 4 results)

  • [Journal Article] Relationship between mortality and Council of Nutrition Appetite Questionnaire scores in Japanese nursing home residents2019

    • Author(s)
      Mikami Y, Watanabe Y, Edahiro A, Motokawa K, Shirobe M, Yasuda J, Murakami M, Murakami K, Taniguchi Y, Furuya J, Hirano H
    • Journal Title

      Nutrition

      Volume: 57 Pages: 40-45

    • DOI

      10.1016/j.nut.2018.05.030

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Factors affecting the appetites of persons with Alzheimer's disease and mild cognitive impairment.2018

    • Author(s)
      Suma S, Watanabe Y, Hirano H, Kimura A, Edahiro A, Awata S, Yamashita Y, Matsushita K, Arai H, Sakurai T
    • Journal Title

      Geriatr Gerontol Int

      Volume: 18 Pages: 1236-1243

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 歯科医師の認知症対応力向上に向けて 最近の認知症を取り巻く動向2017

    • Author(s)
      平野浩彦、枝広あや子
    • Journal Title

      日本歯科医師会雑誌

      Volume: 70 Pages: 305-314

    • Related Report
      2017 Research-status Report
  • [Journal Article] 顔面および口腔内の過敏症状を有する要介護高齢者の口腔機能および栄養状態に関する実態調査2017

    • Author(s)
      白部麻樹,中山玲奈,平野浩彦,小原由紀,遠藤圭子,渡邊裕,白田千代子
    • Journal Title

      日本公衆衛生雑誌

      Volume: 64 Pages: 351-358

    • NAID

      130006108824

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 認知症グループホームにおける認知症重症度と栄養状態の関連2017

    • Author(s)
      本川佳子,田中弥生,菅洋子,細山田洋子,枝広あや子,平野浩彦,渡邊裕
    • Journal Title

      日本在宅栄養管理学会誌

      Volume: 4 Pages: 1-7

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 認知症患者の歯科治療に対する疑問と問題点 Clinical Question調査から2016

    • Author(s)
      服部佳功, 枝広あや子, 渡邊 裕, 平野浩彦, 古屋純一, 中島純子, 田村文誉, 北川 昇, 堀一浩, 原 哲也, 吉川峰加, 西 恭宏, 永尾 寛, 市川哲雄, 櫻井 薫,
    • Journal Title

      老年歯科医学

      Volume: 31(8) Pages: 3-8

    • NAID

      130005170837

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 歯科衛生士の認知症対応力向上を目指して 新オレンジプランの視点から2016

    • Author(s)
      平野浩彦
    • Journal Title

      日本歯科衛生学会雑誌

      Volume: 11(1) Pages: 25-33

    • NAID

      40020940805

    • Related Report
      2016 Research-status Report
  • [Journal Article] 【終末期における患者さんの"物語り"を考える】 (Chapter 2)「終末期」に歯科衛生士はどのようにかかわることができるか2016

    • Author(s)
      枝広あや子、平野浩彦
    • Journal Title

      デンタルハイジーン

      Volume: 36(12) Pages: 1298-1301

    • Related Report
      2016 Research-status Report
  • [Presentation] The statement of position for dental care and the dental treatment guideline for the elderly peoples with dementia from The Japanese Society of Gerodontology(JSG)2018

    • Author(s)
      Hirohiko Hirano, Ayako Edahiro, Yutaka Watanabe, Tetsuo Itikawa.
    • Organizer
      14th International Congress of the EuGMS
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 要介護高齢者の転帰と栄養関連指標の関係 特別養護老人ホームにおける長期観察研究2017

    • Author(s)
      本川佳子,安田純,枝広あや子,白部麻樹,田中弥生,平野浩彦,渡邉裕
    • Organizer
      第32回日本静脈経腸栄養学会
    • Place of Presentation
      岡山シンフォニーホール(岡山県・岡山市)
    • Year and Date
      2017-02-23
    • Related Report
      2016 Research-status Report
  • [Presentation] アルツハイマー型認知症(AD)とレビー小体型認知症(DLB)の食行動特性の比較検討2017

    • Author(s)
      須磨紫乃,渡邊裕,平野浩彦,枝広あや子,白部麻樹,本川佳子,木村藍,松下健二,荒井秀典,櫻井孝
    • Organizer
      第28回老年歯科医学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] アルツハイマー型認知症高齢者の嚥下機能低下に関連する予知因子の検討2017

    • Author(s)
      白部麻樹,平野浩彦,枝広あや子,小原由紀,森下志穂,本川佳子,村上正治,村上浩史,高城大輔,渡邊裕
    • Organizer
      第28回老年歯科医学会学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Effect of Oral Health Care on Hypersensitivity Syndrome Among the Elderly in Long-Term Care2017

    • Author(s)
      Maki Shirobe,Rena Nakayama,Yuki Ohara,Keiko Endo,Yutaka Watanabe,Hirohiko Hirano,Chiyoko Hakuta
    • Organizer
      The 21st IAGG World Congress of Gerontology &Geriatrics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A Role of MNA-SF as a Predictor for 30-Month Mortality in a Nursing Home in Japan2017

    • Author(s)
      Jun Yasuda,Yutaka Watanabe,Hirohiko Hirano,Ayako Edahiro,Maki Shirobe,Keiko Motokawa,Shuichi Awata
    • Organizer
      The 21st IAGG World Congress of Gerontology &Geriatrics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Eating Dysfunction Accompanying Deterioration of AD on the Basis of Functional Assessment Staging2017

    • Author(s)
      Ayako Edahiro,Hirohiko Hirano,Yutaka Watanabe,Yuki Ohara,Keiko Motokawa,Maki Shirobe,Jun Yasuda,Shuichi Awata
    • Organizer
      The 21st IAGG World Congress of Gerontology &Geriatrics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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