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Verifying the Effects of Smoking Cessation Trial Interventions on Smoking Pregnant Women Using Visualized Biomarker Indicators

Research Project

Project/Area Number 16K12128
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Lifelong developmental nursing
Research InstitutionFukuoka University

Principal Investigator

TSUKAHARA HITOMI  福岡大学, 医学部, 教授 (20555403)

Co-Investigator(Kenkyū-buntansha) 村田 愛  福岡大学, 医学部, 助教 (20714835)
中嶋 恵美子  福岡大学, 医学部, 教授 (30461536)
佐久間 良子  福岡大学, 医学部, 准教授 (80554758)
古賀 綾  福岡大学, 医学部, 助教 (60847515)
Project Period (FY) 2016-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords禁煙 / 喫煙 / 妊産婦 / バイオマーカー / HDL inflammatory index / 精密酸化脂質 / 禁煙支援
Outline of Final Research Achievements

To provide smoking cessation support using biomarker indicators, we measured changes in cotinine levels in maternal and cord blood as well as HDL inflammatory index (HII), which is the antioxidant capacity of HDL. Good antioxidant capacity is associated with low HII levels. It tended to be slightly higher in smokers.
The results of analyzing the psychological processes by which pregnant women decide to smoke or quit smoking showed that pregnant women blame themselves due to the conflict between smoking and its effects on the fetus. As ideas about smoking and smoking cessation are highly individual, it is likely that support that respects those ideas is effective. Due to fears of smoking resumption after the end of the breastfeeding period and upon return to work, there is a need to strengthen support that improves understanding of children’s passive smoking.

Academic Significance and Societal Importance of the Research Achievements

妊娠・産褥期・臍帯血中の継続的なコチニン濃度の変化や、酸化脂質等、精密分析による可視化できるデータを用いて、喫煙が母子に及ぼす影響を禁煙支援教材として活用することは禁煙しようとする認識の強化につながる。さらに、喫煙妊婦には、社会的ハイリスクとされる特定妊婦や虐待関連の妊産婦の中には喫煙妊婦の割合が高いことも指摘されており、妊娠中の喫煙・禁煙者の妊娠中の思いや喫煙や禁煙を決断する過程を探索することによって、生まれる児への喫煙の影響をどのように母親が考えているのか母親としての心理的な変化を含め喫煙を左右する思いに応じた個別性のある禁煙支援プログラム開発に寄与する。

Report

(6 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (1 results)

All 2020

All Presentation (1 results)

  • [Presentation] 妊婦の喫煙・禁煙を決定する心理と影響要因2020

    • Author(s)
      塚原ひとみ 古賀綾 佐久間良子
    • Organizer
      日本看護研究学会九州地方会
    • Related Report
      2020 Annual Research Report

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Published: 2016-04-21   Modified: 2022-01-27  

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