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Evaluation of functional dynamics in the whole brain during memory retrieval

Research Project

Project/Area Number 16K12448
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Cognitive science
Research InstitutionFuture University-Hakodate

Principal Investigator

Sato Naoyuki  公立はこだて未来大学, システム情報科学部, 教授 (70312668)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords脳情報処理 / ニューラルネットワーク / 脳科学 / 記憶 / 認知科学 / 神経科学 / 脳・神経 / 情報工学 / 人工知能
Outline of Final Research Achievements

This project was aimed to evaluate functional dynamics in the whole brain during memory retrieval. We constructed a neural network model of the hippocampus which can encode and recall a 6-min word sequence using distributed semantic representation. Moreover, we evaluated electroencephalogram and functional magnetic resonance imaging during literature reading and found that memory performance was associated with the inhibition of saliency network and default mode network.

Academic Significance and Societal Importance of the Research Achievements

脳では視覚、記憶など分散的に処理されているが、読書などの際にはこれらがうまく連動して働く必要がある。この連動の仕組みを明らかにするために、記憶を司る海馬の神経回路をシミュレーションしたところ、一度の読解経験で数分の文章系列を記憶できた、また、文章読解中の脳波と機能的脳画像を調べた結果、記憶成績はサリエンス回路、デフォルトモード回路と呼ばれる脳の広域ネットワークの活動と関連があることが示された。これらの成果は脳がどのように統合的に働くかを理解する上で重要である。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (10 results)

All 2018 2017 2016

All Journal Article (4 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (5 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results) Book (1 results)

  • [Journal Article] Successful encoding during natural reading is associated with fixation-related potentials and large-scale network deactivation2018

    • Author(s)
      Nayouki Sato, Hiroaki Mizuhara
    • Journal Title

      eNeuro

      Volume: 5(5) Issue: 5 Pages: 1-12

    • DOI

      10.1523/eneuro.0122-18.2018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] ヒト海馬の神経回路モデルの構築2017

    • Author(s)
      佐藤直行
    • Journal Title

      人工知能

      Volume: 32(6) Pages: 851-856

    • NAID

      130007917375

    • Related Report
      2017 Research-status Report
  • [Journal Article] Words-in-sequence memory formed by eye movement sequences during reading: A network model based on theta phase coding.2017

    • Author(s)
      Naoyuki Sato
    • Journal Title

      Neural Processing Letters

      Volume: online Issue: 3 Pages: 1-13

    • DOI

      10.1007/s11063-017-9632-4

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Words-in-sequence memory formed by eye movement sequences during reading: A network model based on theta phase coding2017

    • Author(s)
      Naoyuki Sato
    • Journal Title

      Neural Processing Letters

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Estimation of Student Classroom Attention Using a Novel Measure of Head Motion Coherence2018

    • Author(s)
      Sato N., Tominaga A
    • Organizer
      International Conference on Neural Information Processing 2018 (ICONIP2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] エピソード記憶の神経メカニズム: 「脳を創る」の脳科学研究2018

    • Author(s)
      佐藤直行
    • Organizer
      横浜・函館合同医療研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] An electrocorticogram analysis based on the theoretical coupling between subpopulation network structure and cross-spectral power2018

    • Author(s)
      Naoyuki Sato, Riki Matsumoto, Akihiro Shimotake, Masao Matsuhashi, Takayuki Kikuchi, Takeharu Kunieda, Hiroaki Mizuhara, Ryosuke Takahashi, Akio Ikeda
    • Organizer
      Annual meeting of Society for Neuroscience 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] “意味”をつくるコンテクストの記憶の神経機構2017

    • Author(s)
      佐藤直行
    • Organizer
      人工知能美学芸術展シンポジウム
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Memory of reading literature in a hippocampal network model based on theta phase coding2016

    • Author(s)
      Naoyuki Sato
    • Organizer
      The 23rd International Conference on Neural Information Processing (ICONIP 2016)
    • Place of Presentation
      京都大学(京都府京都市)
    • Year and Date
      2016-10-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Book] Cheng L., Leung A., Ozawa S. (eds) Neural Information Processing. ICONIP 2018. Lecture Notes in Computer Science (vol 11306.)2018

    • Author(s)
      Sato N., Tominaga A.
    • Total Pages
      12
    • Publisher
      Springer(Cham)
    • ISBN
      9783030042233
    • Related Report
      2018 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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