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Establishment of video-analysis-based behavioral index of social stress in mice.

Research Project

Project/Area Number 16K12606
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Risk sciences of radiation and chemicals
Research InstitutionWaseda University

Principal Investigator

Kakeyama Masaki  早稲田大学, 人間科学学術院, 教授 (30353535)

Research Collaborator MISHIMA Hiroyuki  早稲田大学, 人間科学学術院, 教授 (90288051)
ENDO Nozomi  奈良県立医科大学, 研究助教 (90802819)
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords社会行動 / 神経科学 / 衛生学 / トランスレーショナルリサーチ / 有害化学物質 / 社会医学 / 行動神経内分泌学
Outline of Final Research Achievements

"Sociality" is an important brain function to human beings as well as cognitive function, and it is pointed out that exposure to environmental risk factors such as chemical exposures may harm it. In animal experiments, we have revealed that perinatal exposure to dioxin causes social behavioral abnormality, accompanied with brain activity abnormalities in social stress situation. In this research, we succeeded in developing and practicing the analysis index of new mouse social behaviors focusing on social stress, as well as its data analysis algorithm, using the image analysis system.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2018 2017 2016 Other

All Presentation (10 results) (of which Int'l Joint Research: 1 results,  Invited: 7 results) Remarks (1 results)

  • [Presentation] Social Competitive Dominance in Group-Housed Mice.2018

    • Author(s)
      Kakeyama M
    • Organizer
      Social Neural Networks Research Unit Kickoff Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] マウスにおける早期環境要因操作による神経発達障害の形成2017

    • Author(s)
      掛山正心
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 集団生活下のマウス個体識別と行動計測2017

    • Author(s)
      掛山正心
    • Organizer
      日本動物行動関連学会2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 「ASD病態とOXTの薬効メカニズム解明を目指した齧歯類モデル動物の行動解析技術」2016

    • Author(s)
      掛山正心
    • Organizer
      次世代脳プロジェクト2016年冬のシンポジウムAMED企画シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2016-12-19
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 脳発達におけるAhRの役割とダイオキシン発達神経毒性2016

    • Author(s)
      掛山正心
    • Organizer
      環境ホルモン学会第19回研究発表会(シンポジウム講演)
    • Place of Presentation
      つくば
    • Year and Date
      2016-12-08
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] マウス早期離乳が成熟期における集団内社会性行動に及ぼす影響2016

    • Author(s)
      宇治田和佳・遠藤のぞみ・小山博史・掛山正心
    • Organizer
      第25回日本行動神経内分泌研究会
    • Place of Presentation
      熱海
    • Year and Date
      2016-09-13
    • Related Report
      2016 Research-status Report
  • [Presentation] Grin1ミュータントマウスの社会性行動の解析2016

    • Author(s)
      京相和貴・宇治田和佳・若菜茂晴・遠藤のぞみ・掛山正心
    • Organizer
      第25回日本行動神経内分泌研究会
    • Place of Presentation
      熱海
    • Year and Date
      2016-09-13
    • Related Report
      2016 Research-status Report
  • [Presentation] Introduction of symposium: Mouse social behavior, environmental and genetic factors.2016

    • Author(s)
      Masaki Kakeyama
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Early weaning induces high-dominance social behavior of mice under group-housed conditions.2016

    • Author(s)
      Waka Ujita, Nozomi Endo, Daisuke Ichikawa,Toki Saito,Hiroshi Oyama, Masaki Kakeyama.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2016-07-20
    • Related Report
      2016 Research-status Report
  • [Presentation] 「高次脳機能の健康を阻害する幼少期の環境要因と遺伝要因」2016

    • Author(s)
      掛山正心
    • Organizer
      第86回日本衛生学会学術総会シンポジウム
    • Place of Presentation
      旭川
    • Year and Date
      2016-05-11
    • Related Report
      2016 Research-status Report
    • Invited
  • [Remarks]

    • URL

      https://www.waseda.jp/inst/ori/other/2016/06/08/450/

    • Related Report
      2017 Annual Research Report

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Published: 2016-04-21   Modified: 2019-03-29  

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