| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
The pathogenic expression process of Staphylococcus aureus (S.aureus) was mathematically analyzed by employing numerical simulation techniques. The pathogenic gene expression level showed a significant fluctuation in the late incubation period. From a perspective of biophysics, the increasing in fluctuation was identified a presymptom of pathogenic expression. Moreover, an inhibition of the fluctuation arrested the pathogenic expression. The realization of the inhibition could contribute to a development of novel therapeutic system which maintains S.aureus in bacteriostatic condition.
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