• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of the renal rehabilitation program to prevent the decline of renal function

Research Project

Project/Area Number 16K12925
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTohoku University

Principal Investigator

Kohzuki Masahiro  東北大学, 医学系研究科, 教授 (70234698)

Co-Investigator(Kenkyū-buntansha) 伊藤 修  東北大学, 医学系研究科, 大学院非常勤講師 (00361072)
三浦 美佐  筑波技術大学, 保健科学部, 准教授 (30612014)
森 信芳  東北大学, 医学系研究科, 助教 (50463790)
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsリハビリテーション / 慢性腎臓病 / ガイドライン策定 / 効果の検証 / 有害事象 / 保存期CKD / 透析患者 / 機序解明 / 腎臓リハビリテーション / 診療ガイドライン策定 / エビデンスレベル / 出版予定 / 運動療法の有効性 / 診療報酬付与 / 物理療法 / 運動療法 / 進行防止 / 循環器・高血圧 / 腎臓 / 医療・福祉 / 組織・細胞
Outline of Final Research Achievements

We have established the Japanese Society of Renal Rehabilitation in 2011 to evaluate and promote renal rehabilitation (RR). We have first established the clinical guideline as “Renal rehabilitation” in the world. We define RR, including of five major components: such as exercise training, diet & fluid management, medication & medical surveillance, education, psychological & vocational counseling”. The first step to successful RR is ensuring that the clinical prerequisites of anemia control, adequate dialysis, exercise, a well-functioning vascular access, and proper nutrition are in place. In RR, we should improve not only quality of life but also biological lifespan in patients with CKD. RR is a feasible, effective and safe secondary prevention strategy following CKD, and offers a promising model for new field of rehabilitation.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (26 results)

All 2017 2016

All Journal Article (14 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 9 results,  Open Access: 8 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 8 results,  Invited: 1 results) Book (2 results)

  • [Journal Article] Effects of aerobic exercise during hemodialysis session on elderly patients: Results of one-year clinical controlled trial2017

    • Author(s)
      Ryo Yoshizawa, Misa Miura, Shigeru Oowada, Osamu Ito, Masahiro Kohzuki, Teruhiko Maeba
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 1-4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Renal rehabilitation: Present and future perspectives2017

    • Author(s)
      Masahiro Kohzuki
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 5-8

    • NAID

      40022076317

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Renal rehabilitation in patients with chronic kidney disease2017

    • Author(s)
      Osamu Ito
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 9-13

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Renal rehabilitation in patients with diabetic kidney disease2017

    • Author(s)
      Taku Harada, Yosuke Isoe, Masahiro Kohzuki
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 10-14

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] CKD のための腎臓リハビテーション:運動療法を中心に. Geriatric Medicine(老年医学 )2017

    • Author(s)
      上月正博
    • Journal Title

      ライフ・サイエンス

      Volume: 55(12) Pages: 1347-1351

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage2016

    • Author(s)
      Suzuki T, Kanno SI, Abe T. et al
    • Journal Title

      J Am Soc Nephrol.

      Volume: 27 Issue: 7 Pages: 1925

    • DOI

      10.1681/asn.2015060623

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Attenuated a Decrease in Parasympathetic Nervous System Activity after Exercise.2016

    • Author(s)
      Jia T, Ogawa Y, Miura M, Ito O, Kohzuki M.
    • Journal Title

      PLoS One.

      Volume: 3 Issue: 2 Pages: 11-16

    • DOI

      10.1371/journal.pone.0148648

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effects of clofibrate on fatty acid oxidation in the kidney of puromycin-induced nephrotic rats2016

    • Author(s)
      Muroya Y, Ito O
    • Journal Title

      Clin Exp Nephrol

      Volume: 20 Issue: 6 Pages: 862-870

    • DOI

      10.1007/s10157-016-1253-0

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Arterial Stiffness Measured with the Cuff Oscillometric Method Is Predictive of Exercise Capacity in Patients with Cardiac Diseases2016

    • Author(s)
      Tazawa Y, Mori N, Ogawa Y, Ito O, Kohzuki M.
    • Journal Title

      The Tohoku Journal of Experimental Medicine

      Volume: 239 Issue: 2 Pages: 127-134

    • DOI

      10.1620/tjem.239.127

    • NAID

      130005154461

    • ISSN
      0040-8727, 1349-3329
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cognitive dysfunction and malnutrition are independent predictor of dysphagia in patients with acute exacerbation of congestive heart failure.2016

    • Author(s)
      Yokota J, Ogawa Y, Yamanaka S, Takahashi Y, Fujita H, Yamaguchi N, Onoue N, Ishizuka T, Shinozaki T, Kohzuki M.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 11 Pages: e0167326-e0167326

    • DOI

      10.1371/journal.pone.0167326

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 慢性腎臓病患者における運動療法2016

    • Author(s)
      上月正博
    • Journal Title

      腎と骨代謝

      Volume: 29 Pages: 309-315

    • Related Report
      2016 Research-status Report
  • [Journal Article] 腎臓リハビリテーション2016

    • Author(s)
      上月正博
    • Journal Title

      腎・高血圧の最新治療

      Volume: 5 Pages: 37-37

    • Related Report
      2016 Research-status Report
  • [Journal Article] 慢性腎臓病の運動療法とリハビリテーション2016

    • Author(s)
      上月正博
    • Journal Title

      日本透析医会雑誌

      Volume: 31 Pages: 341-348

    • Related Report
      2016 Research-status Report
  • [Journal Article] CKDにおけるリハビリテーション.2016

    • Author(s)
      上月正博.
    • Journal Title

      日本内科学会雑誌

      Volume: 105 Pages: 1296-1302

    • NAID

      130005793589

    • Related Report
      2016 Research-status Report
  • [Presentation] 成人CKDと運動療法2017

    • Author(s)
      上月正博
    • Organizer
      第7回日本腎臓リハビリテーション学会
    • Place of Presentation
      つくば国際会議場(筑波)
    • Year and Date
      2017-02-18
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 高血圧発症前からの運動が食塩感受性と腎障害へ及ぼす影響2017

    • Author(s)
      中村貴裕、伊藤修、山越聖子、佐久山晃裕、須田千尋、森信芳、上月正博
    • Organizer
      第6回日本腎臓リハビリテーション学会
    • Place of Presentation
      つくば国際会議場(筑波)
    • Year and Date
      2017-02-18
    • Related Report
      2016 Research-status Report
  • [Presentation] Effects of high-fructose diet on blood pressure and renal damages in Dahl Salt-Sensitive and Salt-Resistant Rats2017

    • Author(s)
      Xu L, Hu G, Kohzuki M, Ito O
    • Organizer
      International Society of Nephrology Frontiers
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chronic exercise improves the progression of renal cyst and podocyte injury in polycystic kidney disease model rats2017

    • Author(s)
      Qui J, Miura T, Sato Y, Kohzuki M, Ito O
    • Organizer
      International Society of Nephrology Frontiers
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of chronic exercise training on CYP4A/20-HETE system in the kidney of Dahl salt-sensitive rats2017

    • Author(s)
      Takahashi J, Ogawa Y, Sakuyama A, Muroya M, Mori N, Kohzuki M, Ito O
    • Organizer
      International Society of Nephrology Frontiers
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of long-term exercise on liver cyst complicated polycystic kidney disease2017

    • Author(s)
      Sato Y, Miura T, Qiu J, Kohzuki M, Ito O
    • Organizer
      International Society of Nephrology Frontiers
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] (Pro)renin receptor expression in the Kidney of Dahl Salt-Sensitive Rats by High Salt Intake2017

    • Author(s)
      Yamakoshi S, Ito O, Rong R, Ohsaki Y, Nakamura T, Muroya Y, Mori T, Ito S, Takahashi K, Totsune K, Kohzuki M
    • Organizer
      International Society of Nephrology Frontiers
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end-stage renal disease: study protocol for a multicenter controlled trial2016

    • Author(s)
      Miura M, Kohzuki M, Oowada S, Hirayama Y, Ito O, Hirayama A.
    • Organizer
      10th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2016-05-29
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of exercise training in the kidney of polycystic kidney rats.2016

    • Author(s)
      Miura T, Ito O, Komatsu M, Ogawa Y, Muroya Y, Kohzuki M.
    • Organizer
      10th International Society of Physical and Rehabilitation Medicine World Congress
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2016-05-29
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Pitavastatin has antihypertensive and renoprotective effects with upregulation of NO system and down-regulation of oxidative stress in the kidney of spontaneously hypertensive rats.2016

    • Author(s)
      Hu G, Ito O, Rong R, Xu B, Sakuyama A, Miura A, Ogawa Y, Ito D, Kohzuki M.
    • Organizer
      International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2016-05-20
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Book] 新編内部障害のリハビリテーション 第2版2017

    • Author(s)
      上月正博
    • Total Pages
      497
    • Publisher
      医歯薬出版
    • ISBN
      9784263215784
    • Related Report
      2017 Annual Research Report
  • [Book] CKD・透析患者の食事療法と運動療法(中尾俊之編集)2016

    • Author(s)
      上月正博.
    • Publisher
      医薬ジャーナル社
    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi