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Regulation of negative emotions via stimulation of the vagal nerve and its neural basis

Research Project

Project/Area Number 16K13504
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionNagoya University

Principal Investigator

Ohira Hideki  名古屋大学, 情報学研究科, 教授 (90221837)

Co-Investigator(Renkei-kenkyūsha) SAKAKIBARA Masahito  愛知学院大学, 心身科学部, 教授 (10221996)
MATSUNAGA Masahiro  愛知医科大学, 医学部, 講師 (00533960)
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords生理 / 迷走神経 / 感情 / 実験系心理学
Outline of Final Research Achievements

This study aimed to examine whether stimulation of the vagal nerve activity which is important for regulation of negative emotions can dampen responses in negative emotions, sympathetic nerve, endocrine, and inflammation systems, by using transcutaneous vagus nerve stimulation (tVNS). However, it has been found that the legal regulation prevents import of the devise of tVNS into Japan. Thus, we tried another method of vagal stimulation, that is slow paced respiration with a pace of 6 cpm. Study 1 showed that this method can significantly enhance the vagal nerve activity, evaluated by heart rate variability. However, Study 2 revealed no effects of vagal nerve stimulation to dampen responses accompanying experiences of negative emotions. It is inferred that the effect size of the paced respiration is relatively small, and other methods which can more robustly enhance vagal nerve activity should be explored.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (8 results)

All 2017 2016 Other

All Int'l Joint Research (1 results) Journal Article (4 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (3 results) (of which Invited: 2 results)

  • [Int'l Joint Research] リール大学(フランス)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Predictive coding, interoception, and affect2017

    • Author(s)
      大平英樹
    • Journal Title

      Emotion Studies

      Volume: 3 Issue: 1 Pages: 2-12

    • DOI

      10.20797/ems.3.1_2

    • NAID

      130006306883

    • ISSN
      2189-7425
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 内受容感覚に基づく行動の制御2017

    • Author(s)
      大平英樹
    • Journal Title

      BRAIN and NERVE-神経研究の進歩

      Volume: 69 Pages: 383-395

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 脳活動の同期を導くメカニズム-定藤論文へのコメント-2016

    • Author(s)
      大平英樹
    • Journal Title

      心理学評論

      Volume: 59 Pages: 283-291

    • NAID

      130006337919

    • Related Report
      2016 Research-status Report
  • [Journal Article] 価値・予測・誤差-社会性を支える意思決定システム-2016

    • Author(s)
      大平英樹
    • Journal Title

      エモーション・スタディーズ

      Volume: 2 Pages: 46-55

    • NAID

      130007055737

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 感情神経科学の25年2017

    • Author(s)
      大平英樹
    • Organizer
      日本感情心理学会第25回大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ポジティブ感情の神経生理的基盤2017

    • Author(s)
      大平英樹
    • Organizer
      第76回日本公衆衛生学会総会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 母子の心臓活動の同期-内受容感覚における予測的処理の発達2017

    • Author(s)
      大平英樹
    • Organizer
      日本心理学会第81回大会
    • Related Report
      2017 Annual Research Report

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Published: 2016-04-21   Modified: 2019-03-29  

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