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Single molecule chirality sensing

Research Project

Project/Area Number 16K13647
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nano/Microsystems
Research InstitutionHokkaido University

Principal Investigator

Sasaki Keiji  北海道大学, 電子科学研究所, 教授 (00183822)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsナノマイクロセンサー / キラリティー測定 / 分子センシング / 局在プラズモン
Outline of Final Research Achievements

In this study, we developed a method for creating novel plasmonic systems that not only focusing a light but also control the shape of light at the nano-scale. During the period, we designed the gold nanostructure optimally by numerical analysis and succeeded in obtaining the design guidelines for forming nano-sized circular polarization field and/or the optical vortex in the gold nanostructure. Based on this finding, the numerically designed structures were fabricated using nano-processing technology, and we succeeded to obtain the gold nanostructures with characteristics that numerically predicted. Furthermore, we experimentally tried to control the motion of nanoparticles by using a nano-sized circularly-polarized optical field induced at the nano-gap and succeeded in observing the nano-scale orbital rotation of a trapped nanoparticle.

Academic Significance and Societal Importance of the Research Achievements

分子のキラリティー識別は、医薬品・農薬・香料の開発等、様々な分野において重要な課題となっている。これまで、キラリティーの識別には、円二色性測定が用いられているが、計測対象は多数のキラル分子の集団平均であり、個々の分子を識別し選別することは不可能である。本研究では、光をナノサイズまで小さくするだけでなく、その「形」をも制御する我々独自の光ナノ成形技術を開発し、誘起したナノ円光場により光捕捉されたナノ粒子がナノスケールの軌道回転運動を起こすことを確認した。この成果は、光のナノ形状の制御により個々の分子・分子集合体を超高感度に計測する新規センシング技術に繋がるものと期待される。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (48 results)

All 2018 2017 2016 Other

All Int'l Joint Research (1 results) Journal Article (16 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 13 results,  Open Access: 8 results,  Acknowledgement Compliant: 4 results) Presentation (27 results) (of which Int'l Joint Research: 22 results,  Invited: 24 results) Remarks (2 results) Patent(Industrial Property Rights) (1 results) Funded Workshop (1 results)

  • [Int'l Joint Research] 台湾交通大学(台湾)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Trapping and Deposition of Dye-Molecule Nanoparticles in the Nanogap of a Plasmonic Antenna2018

    • Author(s)
      Christophe Pin, Shutaro Ishida, Genta Takahashi, Kota Sudo, Tuyoshi Fukaminato, Keiji Sasaki
    • Journal Title

      ACS Omega

      Volume: 3 Issue: 5 Pages: 4878-4883

    • DOI

      10.1021/acsomega.8b00282

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] White light induced photo-thermal switching in a graphene-flake-mixed ZnO nanoparticle random laser2018

    • Author(s)
      Hideki Fujiwara, Ryo Niyuki, Keiji Sasaki
    • Journal Title

      Journal of Physics Communications

      Volume: 2 Issue: 3 Pages: 035022-035022

    • DOI

      10.1088/2399-6528/aab2d3

    • NAID

      120006471029

    • Related Report
      2018 Annual Research Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nanofocusing of structured light for quadrupolar light-matter interactions2018

    • Author(s)
      Kyosuke Sakai, Takeaki Yamamoto, Keiji Sasaki
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 7746-7746

    • DOI

      10.1038/s41598-018-26175-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Enhanced water splitting under modal strong coupling conditions2018

    • Author(s)
      X. Shi, K. Ueno, T. Oshikiri, Q. Sun, K. Sasaki, H. Misawa
    • Journal Title

      Nature Nanotechnol.

      Volume: 13 Issue: 10 Pages: 953-958

    • DOI

      10.1038/s41565-018-0208-x

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Magnetic Response of Random Lasing Modes in a ZnO nanoparticle film deposited on a NiFe thin film2018

    • Author(s)
      Hideki Fujiwara, Hideo Kaiju, Junji Nishii, Keiji Sasaki
    • Journal Title

      Applied Physics Letters

      Volume: 113 Issue: 13 Pages: 131108-131108

    • DOI

      10.1063/1.5040720

    • NAID

      120006725825

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Amplified spontaneous emission from a surface-modified GaN film fabricated under pulsed intense UV laser irradiation2018

    • Author(s)
      Hideki Fujiwara, Keiji Sasaki
    • Journal Title

      Applied Physics Letters

      Volume: 113 Issue: 17 Pages: 171606-171606

    • DOI

      10.1063/1.5040551

    • NAID

      120006732894

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of a nano-particle rotation using a plasmonic trimer nano-structure2017

    • Author(s)
      S. Ishida、 K.Sudo、K.Sasaki
    • Journal Title

      Proceedings SPIE 10252, Optical Manipulation Conference

      Volume: 10252 Pages: 1025210-1025210

    • DOI

      10.1117/12.2275410

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Localized field control at the nano-scale2017

    • Author(s)
      Hideki Fujiwara, Yuki Yasuda, Hiroaki Orita, Shutaro Ishida, and Keiji Sasaki
    • Journal Title

      Proceedings of SPIE

      Volume: 10252 Pages: 1025216-1025216

    • DOI

      10.1117/12.2269158

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Nano-particle rotation using a gap-mode plasmonic field of nano-structure2017

    • Author(s)
      Ishida Shutaro、Sudo Kota、Sasaki Keiji
    • Journal Title

      Proceedings of Opto-Electronics and Communications Conference (OECC) and Photonics Global Conference (PGC)

      Volume: 17358908 Pages: 8114976-8114976

    • DOI

      10.1109/oecc.2017.8114976

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fabrication of low-threshold ZnO nanorod array random laser using a laser-induced hydrothermal synthesis2017

    • Author(s)
      Fujiwara Hideki、Sasaki Keiji
    • Journal Title

      Proceedings of the Optofluidics 2017

      Volume: - Pages: 04196-04196

    • DOI

      10.3390/optofluidics2017-04196

    • Related Report
      2017 Research-status Report
    • Open Access
  • [Journal Article] Double threshold behavior in a resonance-controlled ZnO random laser2017

    • Author(s)
      R. Niyuki, H. Fujiwara, T. Nakamura, Y. Ishikawa, N. Koshizaki, T. Tsuji, and K. Sasaki
    • Journal Title

      APL Photonics

      Volume: 2 Issue: 3 Pages: 036101-036101

    • DOI

      10.1063/1.4974334

    • NAID

      120006220002

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 光の形2017

    • Author(s)
      笹木 敬司
    • Journal Title

      光学

      Volume: 46 Pages: 79-79

    • Related Report
      2016 Research-status Report
  • [Journal Article] 多重極子プラズモン場の光渦による励振2017

    • Author(s)
      酒井 恭輔、笹木 敬司
    • Journal Title

      光学

      Volume: 46 Pages: 80-83

    • Related Report
      2016 Research-status Report
  • [Journal Article] ZnO nanorod array random lasers fabricated by a laser-induced hydrothermal growth2016

    • Author(s)
      H. Fujiwara, T. Suzuki, R. Niyuki and K. Sasaki
    • Journal Title

      New J. Phys.

      Volume: 8 Issue: 10 Pages: 103046-103046

    • DOI

      10.1088/1367-2630/18/10/103046

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Quadrupole lattice resonances in plasmonic crystal excited by cylindrical vector beams2016

    • Author(s)
      K. Sakai, K. Nomura, T. Yamamoto, T. Omura and K. Sasaki
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1

    • DOI

      10.1038/srep34967

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Detailed Observation of Multiphoton Emission Enhancement from a Single Colloidal Quantum Dot Using a Silver-Coated AFM Tip2016

    • Author(s)
      H. Takata, H. Naiki, L. Wang, H. Fujiwara, K. Sasaki, N. Tamai, and S. Masuo
    • Journal Title

      Nano Lett.

      Volume: 16 Issue: 9 Pages: 5770-5778

    • DOI

      10.1021/acs.nanolett.6b02479

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Optical Manipulation with Linear and Angular Momenta in Nano-Space2018

    • Author(s)
      Keiji Sasaki
    • Organizer
      The International Symposium on Plasmonics and Nanophotonics (iSPN2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nano-Space Manipulation with Designed Optical and Plasmonic Fields2018

    • Author(s)
      Keiji Sasaki
    • Organizer
      The 12th International Conference on Excitonic and Photonic Processes in Condensed Matter and Nano Materials (EXCON2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nano-Material Optical Manipulation2018

    • Author(s)
      Keiji Sasaki
    • Organizer
      The 7th Summer Course and Workshop on“Emergent Functional Matter Science”
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Interactions of Plasmonic Nano-Vortex Fields with Nanoparticles and Molecules2018

    • Author(s)
      Keiji Sasaki
    • Organizer
      Progress In Electromagnetics Research Symposium (PIERS2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Conversion and Inversion of Plasmonic Angular Momenta in Nano-Space2018

    • Author(s)
      Keiji Sasaki
    • Organizer
      SPIE Optics & Photonics
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Localized field control by plasmonic mode interference2018

    • Author(s)
      Hideki Fujiwara, Keiji Sasaki
    • Organizer
      8th International Conference on Metamaterials, Photonic Crystals and Plasmonics (META2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] プラズモニックナノ渦場による物質マニピュレーション2018

    • Author(s)
      笹木 敬司
    • Organizer
      固体物理セミナー
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] ナノ光電場制御による分子・分子集合体の自在操作と精密化2018

    • Author(s)
      笹木 敬司
    • Organizer
      レーザー学会学術講演会第38回年次大会 シンポジウム「光圧による物質操作の新展開」
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Nano-Manipulation with Plasmonic Chiral Fields2017

    • Author(s)
      K. Sasaki, S. Ishida,
    • Organizer
      The 8th International Conference on Surface Plasmon Photonics(SPP8)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Efficient Light Coupling to Plasmonic Nanostructures2017

    • Author(s)
      K. Sasaki
    • Organizer
      Optical Nanofibre Applications (ONNA2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Plasmonic Nano-Manipulation Using Angular Momenta2017

    • Author(s)
      K. Sasaki
    • Organizer
      The Second A3 Metamaterials Forum
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Nano-Scale Optical Manipulation using Designed Plasmonic Fields2017

    • Author(s)
      K. Sasaki
    • Organizer
      The 6th Hsinchu Summer Course and Workshop
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] ナノ光マニピュレーション技術2017

    • Author(s)
      笹木 敬司
    • Organizer
      第64回 PST-net 例会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Interference of Plasmonic Vortex Fields with Different Angular Momenta2017

    • Author(s)
      K. Sasaki, H. Fujiwara
    • Organizer
      8th International Conference on Metamaterials, Photonic Crystals and Plasmonics (META 2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Plasmonic Nano-Shaping & Nano-Manipulation2017

    • Author(s)
      K. Sasaki, M.Ide
    • Organizer
      SPIE Optics & Photonics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Plasmonic Manipulation with Nano-Vortex Fields2017

    • Author(s)
      K. Sasaki
    • Organizer
      The 24th Congress of the International Commission for Optics (ICO-24)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Optical Manipulation Using Designed Plasmonic Fields2017

    • Author(s)
      K. Sasaki
    • Organizer
      The International Nanophotonics Symposium (INP-2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] マイクロ・ナノ光共振器による物質操作2017

    • Author(s)
      笹木 敬司
    • Organizer
      第24回 レーザー夏の学校
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Whispering Gallery Mode Plasmonic Nano-Cavities and Their Interaction with Nanoparticles and Molecules2017

    • Author(s)
      K. Sasaki
    • Organizer
      653. WE-Heraeus-Seminar: Optical Microcavities and Their Applications (WOMA2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] ナノ光成形で拓く物理とその応用2017

    • Author(s)
      笹木 敬司
    • Organizer
      第28回 光物性研究会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Angular momentum transfer from photons to plasmons2017

    • Author(s)
      K. Sakai, K. Sasaki
    • Organizer
      JSPS-EPSRC symposium
    • Place of Presentation
      London(UK)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Control of Spoof Localized Surface Plasmons by Vortex of Light in Terahertz Region2016

    • Author(s)
      S. Morimoto, T. Arikawa, F. Blanchard, K. Sakai, K. Sasaki, K. Tanaka
    • Organizer
      41st International Conference on Infrared, Millimeter and Terahertz Wave (IRMMW-THZ 2016)
    • Place of Presentation
      Copenhagen(Denmark)
    • Year and Date
      2016-09-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Observation and Control of Spoof Localized Surface Plasmons Using Terahertz Near-field Microscope Region2016

    • Author(s)
      S. Morimoto, T. Arikawa, F. Blanchard, K. Sakai, K. Sasaki, K. Tanaka
    • Organizer
      41st International Conference on Infrared, Millimeter and Terahertz Wave (IRMMW-THZ 2016)
    • Place of Presentation
      Copenhagen(Denmark)
    • Year and Date
      2016-09-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] White Light Induced Mode Switching in a Graphene Flake Mixed ZnO Random Laser2016

    • Author(s)
      R. Niyuki, H. Fujiwara and K. Sasaki
    • Organizer
      Photonics and Fiber Technology Congress (Nonlinear Photonics)
    • Place of Presentation
      Sydney(Australia)
    • Year and Date
      2016-09-05
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Realization of Low Threshold ZnO Nanorod Array Random Lasers Using a Laser-Induced Hydrothermal Synthesis2016

    • Author(s)
      H. Fujiwara, T. Suzuki, R. Niyuki and K. Sasaki
    • Organizer
      Photonics and Fiber Technology Congress (Nonlinear Photonics)
    • Place of Presentation
      Sydney(Australia)
    • Year and Date
      2016-09-05
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Interference of nano-vortex fields formed by plasmonic cavities2016

    • Author(s)
      K. Sasaki
    • Organizer
      META’16, the 7th International Conference on Metamaterials, Photonic Crystals and Plasmonics
    • Place of Presentation
      Malaga(Spain)
    • Year and Date
      2016-07-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Resonance-controlled Random Lasers and Their Possible Applications2016

    • Author(s)
      H. Fujiwara and K. Sasaki
    • Organizer
      The 6th International Multidiscipline Conference on Optofluidics
    • Place of Presentation
      Beijing(China)
    • Year and Date
      2016-07-24
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Remarks]

    • URL

      http://optsys.es.hokudai.ac.jp/

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://optsys.es.hokudai.ac.jp/

    • Related Report
      2016 Research-status Report
  • [Patent(Industrial Property Rights)] 分光装置2018

    • Inventor(s)
      笹木 敬司、藤原 英樹、石原 一
    • Industrial Property Rights Holder
      笹木 敬司、藤原 英樹、石原 一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-163206
    • Filing Date
      2018
    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] Workshop on Quantum and Nanoscale Photonics2017

    • Place of Presentation
      Hokkaido University(Sapporo, Japan)
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2022-02-22  

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