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Electrode-embedded low-aspect-ratio pores for single-particle shape analysis

Research Project

Project/Area Number 16K13652
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nano/Microsystems
Research InstitutionOsaka University

Principal Investigator

Tsutsui Makusu  大阪大学, 産業科学研究所, 准教授 (50546596)

Project Period (FY) 2016-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywordsナノポア / バイオナノテクノロジー / センサ / マイクロ・ナノデバイス / バイオセンサ / ナノマイクロセンサー
Outline of Final Research Achievements

In this research, a capability of low thickness-to-diameter aspect ratio pore sensors for measuring single-particle shape was investigated. For this, a surrounding-gate electrode-embedded pore was fabricated on a silicon wafer using MEMS technologies. The resistive pulse measurements revealed peculiar feature in the ionic spike signal patterns that reflect the morphologies of single-particles translocated through a channel having appropriate size and length, whereby provided a proof-of-concept of single-particle shape analysis using low-aspect-ratio pores.

Report

(2 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (8 results)

All 2017 2016

All Journal Article (3 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (4 results) (of which Invited: 3 results) Book (1 results)

  • [Journal Article] Short channel effects on electrokinetic energy conversion in solid-state nanopores2017

    • Author(s)
      Yan Zhang, Yuhui He, Makusu Tsutsui, Xiang Shui Mao, and Masateru Taniguchi
    • Journal Title

      Scientific Reports

      Volume: 印刷中

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Electrical trapping mechanism of single-microparticles in a pore sensor2016

    • Author(s)
      A. Arima, M. Tsutsui, Y. He, S. Ryuzaki, and M. Taniguchi
    • Journal Title

      AIP Advance

      Volume: 6 Issue: 15 Pages: 155501-155501

    • DOI

      10.1088/1361-6528/aa5e66

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 66.Salt-gradient approach for regulating capture-to-translocation dynamics of DNA with nanochannel sensors2016

    • Author(s)
      Yuhui He, Makusu Tsutsui, Ralph Scheicher, Xiang Shui Miao, and Masateru Taniguchi
    • Journal Title

      ACS Sensors

      Volume: 1 Issue: 6 Pages: 807-816

    • DOI

      10.1021/acssensors.6b00176

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Machine Learning Approach for Resistive-Pulse Analysis in Pore Sensors2017

    • Author(s)
      Makusu Tsutsui
    • Organizer
      New Quantum Materials and Transport Seminar
    • Place of Presentation
      National Shiao Tung University
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Machine Learning Approach for Resistive-Pulse Analysis in Pore Sensors2017

    • Author(s)
      Makusu Tsutsui
    • Organizer
      Research Center for Applied Sciences Seminar
    • Place of Presentation
      Academia Sinica
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Single-particle analysis using low-aspect-ratio pore sensors2017

    • Author(s)
      Makusu Tsutsui
    • Organizer
      Analytix 2017
    • Place of Presentation
      ヒルトン福岡シーホーク
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 超低アスペクト比ポアによる細菌形状識別2016

    • Author(s)
      筒井真楠,横田一道, 有馬彰秀, 殿村渉, 谷口正輝, 鷲尾隆, 川合知二
    • Organizer
      第77回応用物理学会秋季学術講演会
    • Place of Presentation
      朱鷺メッセ
    • Related Report
      2016 Annual Research Report
  • [Book] Nanofluidics: Edition 22016

    • Author(s)
      Yuhui He, Makusu Tsutsui, and Masateru Taniguchi
    • Total Pages
      39
    • Publisher
      Royal Chemical Society
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2018-03-22  

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