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Elucidation of the 3D nanosapce cage effect and arraying of nanoparticles in liquid phase

Research Project

Project/Area Number 16K13653
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nano/Microsystems
Research InstitutionOsaka Prefecture University

Principal Investigator

Xu Yan  大阪府立大学, 工学(系)研究科(研究院), 准教授 (90593898)

Research Collaborator SHIMATANI Yuji  
KAWABATA Toshiyuki  
TSUJIKAWA Takehiro  
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywordsナノ流体デバイス / 3Dナノ空間ケージ効果 / ナノ粒子 / アレイ化 / Nano-in-Nano集積化 / ナノ流路 / ナノチャネル / 3Dナノ空間 / ケージ効果
Outline of Final Research Achievements

A new cage effect existing in an open 3D nanospace was previously observed by us. We named this new cage effect as 3D nanospace cage effect. In this study, to elucidate the mechanism of the effect, the dynamic behaviors of single nanoparticles trapped in 3D open nanospaces within nanochannels were investigated, and the interactions between the trapped nanoparticles and the surface walls of the open nanospaces were clarified. Furthermore, to achieve single nanoparticle arrays in the liquid phase based on the elucidated mechanism, the optimal trapping conditions associated with nanofluids and nanospace structures were clarified by using our original experimental system. These results are very useful to achieve spatiotemporal precision control of nanoparticles in liquid phase, which will significantly improve the performances of a variety of applications utilizing nanoparticles in the fields of analytical chemistry, optical devices, energy, bioengineering and medicine.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (34 results)

All 2018 2017 2016 Other

All Journal Article (4 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 3 results,  Open Access: 1 results) Presentation (26 results) (of which Int'l Joint Research: 16 results,  Invited: 14 results) Book (2 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Nanofluidics: a New Arena for Materials Science2018

    • Author(s)
      Yan Xu
    • Journal Title

      Advanced Materials

      Volume: 30 Issue: 3 Pages: 1702419-1702419

    • DOI

      10.1002/adma.201702419

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1兆分の1 mLの水を自在に制御できる技術2016

    • Author(s)
      許 岩
    • Journal Title

      自動車技術 (「超の世界」)

      Volume: 70 Pages: 122-123

    • Related Report
      2016 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Bridging world-to-nanofluidics interfaces through nano-in-nano integration technology2016

    • Author(s)
      Xu Y.
    • Journal Title

      IEEE Micro-NanoMechatronics and Human Science (MHS), 2016 International Symposium on

      Volume: 1 Pages: 16603900-16603900

    • DOI

      10.1109/mhs.2016.7824225

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Antifouling Surface Modification of Nanochannels Using a Silanized Phospholipid Monomer.2016

    • Author(s)
      Xu Y., Wu Q.
    • Journal Title

      Proceedings of Micro Total Analysis Systems 2016

      Volume: 1 Pages: 1152-1153

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Nanofluidics: A New Arena for Chemistry,Biology,and Materials Science2018

    • Author(s)
      Yan Xu
    • Organizer
      Shenzhen University
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] NanoBioChem Integration at Femtoliter,Attoliter,and Single-Molecule Scales through Nanofluidics2018

    • Author(s)
      Yan Xu
    • Organizer
      11th Shenzhen Symposium on Biomedical and Health Engineering
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 超微量流体を制御するNano-in-Nano集積化技術を駆使したナノ化学システム2017

    • Author(s)
      許岩
    • Organizer
      JSTオープンイノベーションフェアWEST2017 ~関西発 大学技術シーズ見本市~
    • Place of Presentation
      ブリーゼプラザ803号室, 大阪, 日本
    • Year and Date
      2017-02-22
    • Related Report
      2016 Research-status Report
  • [Presentation] Nanofluidics for Single-Cell Proteomics with Single-Molecule Sensitivity2017

    • Author(s)
      Yan Xu
    • Organizer
      The 7th International Multidisciplinary Conference on Optofluidics 2017 (Optofluidics 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nano-in-Nano集積化による1分子液滴の作製2017

    • Author(s)
      川岸啓人、山口晃司、川又修一、河村裕一、許岩
    • Organizer
      化学とマイクロ・ナノシステム学会第35回研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] デジタルナノチャネルを用いた細胞死に関わるタンパク質の1分子検出2017

    • Author(s)
      藤本学都、呉倩、許岩
    • Organizer
      第77回分析化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ナノ流路in-situでの電気的な温度測定・制御2017

    • Author(s)
      中嶋太一、許岩
    • Organizer
      第77回分析化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] NanoBioChem Integration at Femtoliter,Attoliter,and Single-Molecule Scales through Nanofluidics2017

    • Author(s)
      Yan Xu
    • Organizer
      Lecture of Southern University of Science and Technology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nanofluidics: A New Arena for Chemistry,Biology,and Materials Science2017

    • Author(s)
      Yan Xu
    • Organizer
      2017 SIAT-OPU Workshop on Nanofluidics and Biomedical Engineering
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Size separation of nanoparticles by using aifA.2017

    • Author(s)
      Satoshi Nishioka,Yan Xu
    • Organizer
      2017 SIAT-OPU Workshop on Nanofluidics and Biomedical Engineering
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] In-situ electrical measurements in 2D nanochennels2017

    • Author(s)
      Taichi Nakajima, Yan Xu
    • Organizer
      2017 SIAT-OPU Workshop on Nanofluidics and Biomedical Engineering
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Digital nanochannels with novel phospholipid monomer interfaces for single molecule counting2017

    • Author(s)
      Takato Fujimoto, Qian WU, Yan Xu
    • Organizer
      The 11th NanoSquare Workshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fabrication of hydrophilic/hydrophobic interfaces in nanochannels for molecular manipulation2017

    • Author(s)
      Hiroto Kawagishi, Shuichi Kawamata,Yan Xu
    • Organizer
      The 11th NanoSquare Workshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Nanofluidics: A New Arena for Chemistry,Biology,and Materials Science2017

    • Author(s)
      Yan Xu
    • Organizer
      Shanghai University of Traditional Chinese Medicine
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] NanoBioChem Integration at Femtoliter,Attoliter,and Single-Molecule Scales through Nanofluidics2017

    • Author(s)
      Yan Xu
    • Organizer
      Shanghai Jiao Tong University
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 究極化学に向けた極微量フロー制御と計測2017

    • Author(s)
      許 岩
    • Organizer
      第106回テクノラボツアー:最新『フロー合成プロセス技術』の紹介
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 極微量流体を制御するNano-in-Nano 集積化技術を駆使したナノ化学システム2017

    • Author(s)
      許 岩
    • Organizer
      第107回テクノラボツアー:『夢を実現する工学-化学工学分野の最先端研究』
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Bridging World-to-Nanofluidics Interfaces through Nano-in-Nano Integration Technology.2016

    • Author(s)
      Xu Y.
    • Organizer
      27th 2016 International Symposium on Micro-NanoMechatronics and Human Science (From Micro & Nano Scale Systems to Robotics & Mechatronics Systems)
    • Place of Presentation
      Noyori memorial Conference Hall, Nagoya University, Nagoya, Japan
    • Year and Date
      2016-11-28
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Antifouling surface Modification of Nanochannels Using a Silanized Phospholipid Monomer.2016

    • Author(s)
      Xu Y., Wu Q.
    • Organizer
      The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016)
    • Place of Presentation
      Covention Center Dublin, Dublin, Ireland
    • Year and Date
      2016-10-09
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Nano-in-Nano集積化技術を用いたナノ粒子のアレイ化.2016

    • Author(s)
      島谷雄士、許岩
    • Organizer
      日本分析化学会第65年会
    • Place of Presentation
      北海道大学工学部, 札幌, 日本
    • Year and Date
      2016-09-14
    • Related Report
      2016 Research-status Report
  • [Presentation] Fabrication of Nanoparticle Arrays by Using Nano-in-Nano Integration technology.2016

    • Author(s)
      Shimatani Y., Xu Y.
    • Organizer
      RSC Tokyo International Conference 2016
    • Place of Presentation
      Makuhari-Messe, Chiba, Japan
    • Year and Date
      2016-09-08
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Fabrication of smartbiointerfaces in nanochannels with a thiolatedtemperature-responsivepolymer.2016

    • Author(s)
      Xu Y.
    • Organizer
      10th World Biomaterials Congress(WBC2016)
    • Place of Presentation
      Montreal Convention Center, Montreal, Canada
    • Year and Date
      2016-05-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Beyond the Bare Nanochannels: Exploring the Possibilities of Nanofluidics through Nano-in-Nano Integration.2016

    • Author(s)
      Xu Y.
    • Organizer
      State Key Laboratory of Analog and Mixed-Signal VLSI (AMSV) Distinguished Lecture
    • Place of Presentation
      Macau University, Macau, China
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Femtoliter-Scale Nanofluidic Analysis Enabled by Nano-in-Nano Integration Technology.2016

    • Author(s)
      Xu Y.
    • Organizer
      3rd Asian Symposium for Analytical Sciences (3rd ASAS)
    • Place of Presentation
      Hokkaido University Faculty of Engineering Academic Lounge 3, 札幌, 日本
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Nanobio Interfaces Innovation Enables Nanofluidics2016

    • Author(s)
      Xu Y.
    • Organizer
      General Methodology, Critical Techniques, and Nanobio Applications
    • Place of Presentation
      四川大学, Sichuan, China
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Nano-in-Nano 集積化技術を駆使したナノ化学システムの開発2016

    • Author(s)
      許岩
    • Organizer
      化学工学会関西支部 第4回技術シーズフォーラム
    • Place of Presentation
      同志社大学室町キャンパス, 京都, 日本
    • Related Report
      2016 Research-status Report
    • Invited
  • [Book] Handbook of Modern Coating Technologies. Future Perspectives and Advanced Applications, Volume 52018

    • Author(s)
      Yan Xu, Madoka Takai, Kazuhiko Ishihara
    • Total Pages
      35
    • Publisher
      Elsevier
    • Related Report
      2017 Annual Research Report
  • [Book] ナノメディシンの分子科学2018

    • Author(s)
      許 岩
    • Total Pages
      2
    • Publisher
      講談社サイエンティフィク
    • Related Report
      2017 Annual Research Report
  • [Remarks] 許研究室HP

    • URL

      http://www.chemeng.osakafu-u.ac.jp/group8/index.html

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
  • [Patent(Industrial Property Rights)] 粒子捕捉装置及び粒子捕捉方法2017

    • Inventor(s)
      許 岩
    • Industrial Property Rights Holder
      許 岩
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-098247
    • Filing Date
      2017
    • Related Report
      2017 Annual Research Report

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Published: 2016-04-21   Modified: 2021-01-27  

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