| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
The creation of molecular catalysts bearing novel core frameworks offers new systems for organic reactions, and it will advance manufacturing technologies. In this study, we developed organocatalysts utilizing planar chiral medium-size ring structures bearing an olefin and a chiral platform including the olefin, as olefins have hardly been utilized for functional groups for catalysis.
Using trans-cyclooctene catalysts, which were newly synthesized, halogenations of alkenes were investigated; high catalytic activity and large substituent effects, which are important for additional design of the catalysts, were observed. In addition, the hydrophobicity of the hydrocarbon organocatalysts could be applied to phase-transfer catalysis. Furthermore, they were also useful as asymmetric ligands for transition metal catalysts, affording high enantioselectivity.
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