| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
One of the subject of this project is to realize efficient generation of simple enols under neutral conditions without using acid or base catalysis. Appropriately designed unsaturated carbonyl compounds readily undergo 1,5-hydrogen shift under photoirradiation conditions to give corresponding dienols efficiently. In addition, photo-excitation of alkanoylsilanes bearing a reactive gamma-hydrogen promoted Norrish type-II fragmentation to furnish silyl-substituted enols, which are rather stable in anhydrous solution. Applications of these enol generation methodologies to synthetic reactions were also investigated.
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