| Project/Area Number |
16K14075
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Polymer/Textile materials
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Research Collaborator |
TANAKA Hiroshi
SAKAI Takamasa
SAWADA Toshiki
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | セルロース / 酵素合成 / 構造体 |
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| Outline of Final Research Achievements |
The self-assembly of biomolecules into highly regular structures is essential in the construction of biological tissues and organs. Various biomolecular assemblies composed of nucleic acids, peptides, and lipids have been utilized as molecular building units for self-assembled materials. However, crystalline oligosaccharides have rarely been utilized in self-assembled materials. In this research, multidimensional self-assembled structures of alkylated cellulose oligomers were synthesized via in vitro enzymatic reactions. It was found that the alkyl chain length drastically affected the assembled morphologies and allomorphs of cellulose moieties. The modulation of the intermolecular interactions of cellulose oligomer derivatives by alkyl substituents was highly effective at controlling their assembly into multidimensional structures. This research proposed a new potential of crystalline oligosaccharides for structural components of unique molecular assemblies.
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