| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
To control a drug permeation from the skin surface, a three dimensional skin structure and precise drug permeation measurements are needed. We measured non-invasively the three dimensional skin structure by using a two photon microscopy and the drug permeation through the skin surface by using a confocal microscopy. As our results, the qualitative measurements of the strain of skin surface and the amount of permeated drug through the skin were succeeded. We found the mechanism of drug permeation through the skin surface with the skin extension.
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