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Development of terahertz micro TAS tips for an ultra-small amount of solutions with high sensitivity

Research Project

Project/Area Number 16K14255
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Electron device/Electronic equipment
Research InstitutionOsaka University

Principal Investigator

Kitagishi Keiko  大阪大学, レーザーエネルギー学研究センター, 特任研究員 (20563860)

Co-Investigator(Renkei-kenkyūsha) SERITA Kazunori  大阪大学, レーザー科学研究所, 特任研究員 (00748014)
Research Collaborator OKADA Kosuke  
OHASHI Shohei  
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsテラヘルツデバイス / 超微量溶液分析 / テラヘルツ/赤外材料・素子 / 計測工学
Outline of Final Research Achievements

Microchips for an ultra-small amount of solutions of pico-liter order with high sensitivity of femtomole level has been designed and developed by using near-field emitted terahertz (THz). A GaAs(110) substrate as a THz emitter on which micro channels were fabricated, was provided as an integrated THz microchip combining a THz emitter and a sample solution vessel. Metamaterial structure fabricated on the surface of GaAs brought higher sensitivity. In order to develop disposable microchips, a thin film of polydimethylsiloxane (PDMS) with microchannels stuck on GaAs was designed. By using new microchips, the solutions of biomolecules were measured and evaluated.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] 高空間分解能、高感度テラヘルツ分光のバイオ分野への応用の試み2017

    • Author(s)
      北岸恵子
    • Journal Title

      生産と技術

      Volume: 69(2) Pages: 98-100

    • NAID

      40021176643

    • Related Report
      2017 Annual Research Report
    • Open Access
  • [Presentation] PDMSマイクロチップ流路一体型テラヘルツチップによる微量溶液の測定2018

    • Author(s)
      田家稜平、濱田輝、芹田和則、北岸恵子、川井隆之、川山巌、村上博成、斗内政吉
    • Organizer
      第65回応用物理学会春季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] キャピラリーを用いた分離分析へのテラヘルツ分光検出2017

    • Author(s)
      北岸恵子
    • Organizer
      応用物理学会春季学術講演会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2017-03-14
    • Related Report
      2016 Research-status Report
  • [Presentation] キャピラリーやμ-TASを用いたテラヘルツ分光のバイオ応用の試み2017

    • Author(s)
      北岸恵子、芹田和則、濱田輝、川井隆之、斗内政吉
    • Organizer
      日本生物高分子学会2017年度大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 高空間分解能、高感度テラヘルツ分光のバイオ分野への応用の試み2017

    • Author(s)
      北岸恵子、芹田和則
    • Organizer
      先端テラヘルツ研究とその応用展開
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] テラヘルツ分光に適した新規マイクロ流路デバイス作製の試み2017

    • Author(s)
      芹田和則、濱田輝、北岸恵子、川井隆之、斗内政吉
    • Organizer
      第78回応用物理学会秋季学術講演会
    • Related Report
      2017 Annual Research Report
  • [Presentation] マイクロ流路を用いた生体試料分析への近接場テラヘルツ分光検出法の応用の試み2017

    • Author(s)
      北岸恵子、芹田和則、濱田輝、川井隆之、川山巌、斗内政吉
    • Organizer
      第37回キャピラリー電気泳動シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Application of near-field terahertz spectroscopic detection to micro-flow channels with high sensitivity for biological sample analyses2017

    • Author(s)
      Keiko Kitagishi, Kazunori Serita, Kagayaki Hamada, Iwao Kawayama, Masayoshi Tonouchi, Takayuki Kawai
    • Organizer
      MTSA2017-OptoX- Nano-TeraNano 8
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Patent(Industrial Property Rights)] 測定用デバイス、及びそれを用いた測定装置2016

    • Inventor(s)
      芹田和則、斗内政吉、村上博成、川山巌、北岸恵子
    • Industrial Property Rights Holder
      芹田和則、斗内政吉、村上博成、川山巌、北岸恵子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-08-26
    • Related Report
      2016 Research-status Report
    • Overseas

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Published: 2016-04-21   Modified: 2019-03-29  

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