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Development of palm-sized ion gun and test of cell adhesion-activation for medical applications

Research Project

Project/Area Number 16K14385
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Inorganic materials/Physical properties
Research InstitutionNagoya Institute of Technology

Principal Investigator

Daiko Yusuke  名古屋工業大学, 工学(系)研究科(研究院), 准教授 (70514404)

Co-Investigator(Kenkyū-buntansha) 町田 幸大  兵庫県立大学, 工学研究科, 助教 (20553093)
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsガラス / イオン伝導 / イオン放出 / イオン注入 / 電界放出 / ショットキー / 空間電荷制限電流 / プロトン伝導 / ゾル-ゲル法 / ゾルーゲル法 / 細胞付着 / 細胞活性
Outline of Final Research Achievements

Ion implantation is an effective method for changing surface properties and inducing various functionalities. However, a high vacuum is generally necessary for ion implantation, which limits the range of applications. We made a palm-sized H+. Ag+ amd Cu+ ion emission gun produced using a solid electrolyte. For example, AgI-based glass, known as a super-ion-conducting glass, and Ag+ ion emission is observed from the tip of the glass fiber even at room temperature in a non-vacuum atmosphere. Similarly, a high proton conducting glass-rod was prepared via sol-gel technique, and its tip was sharpened by a meniscus-etching method. The glass-rod shows proton conductivity of 1×10-3 at room temperature after absorption of water molecules. A high ionic current was successfully observed even under non-vacuum atmosphere at room temperature.

Academic Significance and Societal Importance of the Research Achievements

近年イオン注入技術は幅広い分野で注目・検討されている。従来のイオン注入技術では、高エネルギーで試料にイオン注入可能であるが、真空中かつ大型の高額装置のため非汎用であり、イオン注入技術が様々な産業分野に幅広く普及しているとは言いがたい。また生体組織は水分を多く含むため真空下で脱水により失活すると考えられる。本研究では先鋭化したイオン伝導性ガラスに電界を印加する新しい発想によって、非真空の大気圧条件において伝導種イオンが実際にガラス先端から放出され、また放出イオンが抗菌活性を有することを明らかにした。手のひらサイズに小型可能であり、今後イオンの特徴を生かした治療や創薬などが期待される。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (22 results)

All 2019 2018 2017 2016 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (14 results) (of which Int'l Joint Research: 7 results,  Invited: 2 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Palm-sized Ag ion emission gun operated at roomtemperature in non-vacuum atmosphere2018

    • Author(s)
      Yusuke Daiko, Kyohei Segawa, Kodai Machida, Hiroaki Imataka, Sawao Honda, and Yuji Iwamoto
    • Journal Title

      Adv. Engneering Mater.

      Volume: 20 Issue: 9 Pages: 1800198-1800198

    • DOI

      10.1002/adem.201800198

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ag+ ion emission from a sharp Ag2O-Al2O3-P2O5-SiO2 glass-fiber emitter2018

    • Author(s)
      Daiko Yusuke、Segawa Kyohei、Honda Sawao、Iwamoto Yuji
    • Journal Title

      Solid State Ionics

      Volume: 322 Pages: 5-10

    • DOI

      10.1016/j.ssi.2018.04.018

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] H+ emission under room temperature and non-vacuum atmosphere from a sol?gel-derived nanoporous emitter2017

    • Author(s)
      Daiko Yusuke、Mizutani Satoshi、Machida Kodai、Imataka Hiroaki、Honda Sawao、Iwamoto Yuji
    • Journal Title

      Journal of Sol-Gel Science and Technology

      Volume: 83 Issue: 2 Pages: 252-258

    • DOI

      10.1007/s10971-017-4430-z

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of H+ emission gun using a proton conducting glass fiber2016

    • Author(s)
      Y. Daiko, S. Mizutani, K. Segawa, S. Honda, Y. Iwamoto
    • Journal Title

      Proc. IEEE 16th Int. Conf. Nanotech

      Volume: 351 Pages: 351-353

    • DOI

      10.1109/nano.2016.7751521

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] Ag+イオン放出用ガラスのAgメタル/ガラス界面反応と長期安定イオン放出2019

    • Author(s)
      森 裕暉、大幸 裕介、本多 沢雄、岩本 雄二
    • Organizer
      日本セラミックス協会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Ag+ ion emission from sharp-edged Ag+ ion conducting glasses and two emission mechanisms2018

    • Author(s)
      Yusuke Daiko, Hiroki Mori, Sawao Honda, Yuji Iwamoto
    • Organizer
      MRS Fall meeting
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Various ion emissions from nano-sharpened glass fiber emitters2018

    • Author(s)
      Yusuke Daiko, Sawao Honda, Yuji Iwamoto
    • Organizer
      ICG Annual Meeting 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ag+ ion emission from a sharp tip of Ag+ ion conducting glass and Schottky-model analysis2018

    • Author(s)
      Yusuke Daiko, Sawao Honda, Yuji Iwamoto
    • Organizer
      21th International Conference on Advanced Materials & Nanotechnology
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ag+ and H+ emission from sharp-edged glasses under non-vacuum atmosphere2018

    • Author(s)
      Yusuke Daiko, Kyohei Segawa, Sawao Honda, Yuji Iwamoto
    • Organizer
      15th International Conference on the Physics of Non-Crystalline Solids and 14th European Society of Glass Conference
    • Related Report
      2018 Annual Research Report
  • [Presentation] 2成分リン酸塩ガラスMO-P2O5 (M=Ca, Sr, Ba)のM2+周辺局所構造とH+注入ダイナミクス2018

    • Author(s)
      ジョン スミン、大幸裕介、本多沢雄、岩本雄二
    • Organizer
      日本セラミックス協会2017年年会
    • Related Report
      2017 Research-status Report
  • [Presentation] Alkaline-earth metal ion dependence of H+ implantation in phosphate glass by in-situ electrochemical FT-IR analysis2018

    • Author(s)
      ジョン スミン、大幸裕介、本多沢雄、岩本雄二
    • Organizer
      The 34th International Japan-Korea Seminar on Ceramics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] ゾル-ゲル法で作製したプロトン伝導性ガラスの先鋭化による室温大気H+電界放出2017

    • Author(s)
      水谷聖、大幸裕介、本多沢雄、岩本雄二
    • Organizer
      日本セラミックス協会2016年年会
    • Place of Presentation
      日本大学
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
  • [Presentation] ヨウ化銀系Ag+超イオン伝導性ガラスを用いたAg+イオン放出及び長期イオン放出2017

    • Author(s)
      瀬川恭平、水谷聖、大幸裕介、本多沢雄、岩本雄二
    • Organizer
      日本セラミックス協会2016年年会
    • Place of Presentation
      日本大学
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
  • [Presentation] 先鋭化したイオン伝導性ガラスを用いた局所イオン注入技術の開発2017

    • Author(s)
      大幸裕介、瀬川恭平、本多沢雄、岩本雄二
    • Organizer
      第30回日本セラミックス協会秋季シンポジウム
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Ion emission from nano-sharpening glass fiber2016

    • Author(s)
      Y. Daiko, S. Mizutani, K. Segawa, S. Honda, Y. Iwamoto
    • Organizer
      7th International Workshop on Advanced Ceramics
    • Place of Presentation
      Limoges, France
    • Year and Date
      2016-09-26
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] H+ emission using nano-sharpened proton conducting glass fiber2016

    • Author(s)
      S. Mizutani, Y. Daiko, S. Honda, Y. Iwamoto
    • Organizer
      CerSJ-GOMD Joint symposium on Glass Science and Technologies
    • Place of Presentation
      Kyoto
    • Year and Date
      2016-09-13
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] ヨウ化銀系Ag+超イオン伝導性ガラスのナノ先鋭化及びAg+イオン放出2016

    • Author(s)
      瀬川恭平、大幸裕介、本多沢雄、岩本雄二
    • Organizer
      日本セラミックス協会第29回秋季シンポジウム
    • Place of Presentation
      広島大学
    • Year and Date
      2016-09-07
    • Related Report
      2016 Research-status Report
  • [Presentation] Development of H+ emission gun using a proton conducting glass fiber2016

    • Author(s)
      Y. Daiko
    • Organizer
      16th International conference on nanotechnology (IEEE nano)
    • Place of Presentation
      仙台国際会議場
    • Year and Date
      2016-08-23
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] Handbook of Sol-Gel Science and Technology 2nd edition2016

    • Author(s)
      Y. Daiko, Y. Iwamoto
    • Total Pages
      13
    • Publisher
      Springer
    • Related Report
      2016 Research-status Report
  • [Remarks]

    • URL

      http://chempro.web.nitech.ac.jp/index.html

    • Related Report
      2016 Research-status Report
  • [Patent(Industrial Property Rights)] イオン発生器2017

    • Inventor(s)
      大幸裕介、瀬川恭平
    • Industrial Property Rights Holder
      名古屋興教大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-203023
    • Filing Date
      2017
    • Related Report
      2017 Research-status Report
  • [Patent(Industrial Property Rights)] イオン発生器2016

    • Inventor(s)
      大幸裕介, 瀬川恭平
    • Industrial Property Rights Holder
      大幸裕介, 瀬川恭平
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-11-21
    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

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