Neuronal mechanisms for the odor induced eating behaviors in the olfactory cortex
| Project/Area Number |
16K14557
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurophysiology / General neuroscience
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| Research Institution | Doshisha University |
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Principal Investigator |
Manabe Hiroyuki 同志社大学, 研究開発推進機構, 准教授 (80511386)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 嗅覚 / 摂食行動 / 嗅皮質 / Tenia Tecta / 電気生理 / 視床下部 / 摂食 / 電気生理学 / 光遺伝学 / 神経科学 |
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| Outline of Final Research Achievements |
Central olfactory system translates odor information into motivated behaviors including appetitive food approach and eating behaviors. However, it is still unknown how the olfactory cortex controls eating-related behaviors in mammals. We performed retrograde tracing from the mouse lateral hypothalamus, and found that a group of inhibitory cells were clustered in a ventral region of the olfactory peduncle. We named this region as the ventral olfactory nucleus.
To reveal a role of feeding-related behaviors of vTT, we recorded spike activities in the vTT during the eating-related behaviors. We found that vTT neurons respond to distinct behavioral states of feeding behavior. These results suggest that olfactory cortex has an important role for odor induced eating behaviors.
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Report
(3 results)
Research Products
(6 results)
