| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
When eukaryotic cells face with nutrient starvation, they degrade their cytoplasmic materials to adapt the severe environment. Recently, it has been reported that autophagy contributes to degrade RNA in response to starvation. In this study, we aimed to make a list of RNA species selectively degraded by autophagy. We have established an overexpression system of Atg15, which is responsible for the final step of autophagic degradation.
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