| Project/Area Number |
16K14803
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ecology/Environment
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SUGIMOTO Asako 東北大学, 生命科学研究科, 教授 (80281715)
MAKINO Takashi 東北大学, 生命科学研究科, 准教授 (20443442)
MARUYAMA Shinichro 東北大学, 生命科学研究科, 助教 (50712296)
YOKOYAMA Jun 山形大学, 理学部, 教授 (80272011)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 体サイズ進化 / 線虫 / サイズ進化 |
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| Outline of Final Research Achievements |
We purpose to determine candidate genes responsible for the evolution of larger body size of C. inopinata. C. inopinata became larger during developmental L4 to adult stages comparing with C. elegans. Then, we detected 2699 genes which expression patterns differed between C. inopinata and C. elegans. We also detected 42 genes which have been subject to positive selection during the evolution of C. inopinata from other related species. Among them, daf-2 could be detected and this gene encodes the insulin-like growth factor 1 receptor and variant of def-1 in C. elegance became larger. Thus, the results suggest that daf-2 is as an important genes affecting the evolution of large body size of C. inopinata
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