| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Juvenile hormone (JH) represses precocious metamorphosis of larval to adult transitions. Ecdysone-induced protein 93F (E93) functions as an adult specifier gene in the pupal-adult transition. JH is known to repress E93 expression to prevent immature larvae from bypassing the pupal stage and progressing to precocious adult development; however, the molecular mechanism underlying JH-mediated E93 repression remains unknown. Here, I identified a cis- and tran-element concerning the repression, and demonstrated molecular mechanism underlying juvenile hormone-mediated repression of precocious larval-adult metamorphosis.
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