Molecular mechanism underlying juvenile hormone-mediated repression of adult metamorphosis
Project/Area Number |
16K15072
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Insect science
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Research Institution | National Agriculture and Food Research Organization |
Principal Investigator |
Kayukawa Takumi 国立研究開発法人農業・食品産業技術総合研究機構, 生物機能利用研究部門, 主任研究員 (70580463)
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Keywords | 幼若ホルモン / 成虫化決定因子 / 抑制分子メカニズム / 転写因子 / 脱皮・変態 |
Outline of Final Research Achievements |
Juvenile hormone (JH) represses precocious metamorphosis of larval to adult transitions. Ecdysone-induced protein 93F (E93) functions as an adult specifier gene in the pupal-adult transition. JH is known to repress E93 expression to prevent immature larvae from bypassing the pupal stage and progressing to precocious adult development; however, the molecular mechanism underlying JH-mediated E93 repression remains unknown. Here, I identified a cis- and tran-element concerning the repression, and demonstrated molecular mechanism underlying juvenile hormone-mediated repression of precocious larval-adult metamorphosis.
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Report
(3 results)
Research Products
(8 results)