Controlling of the ion channel clustering and collective function by photoresponsive DNA
| Project/Area Number |
16K15178
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General physiology
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| Research Institution | Kanazawa University (2017)
University of Fukui (2016) |
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Principal Investigator |
Sumino Ayumi 金沢大学, 新学術創成研究機構, 助教 (80717140)
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| Co-Investigator(Kenkyū-buntansha) |
神谷 由紀子 名古屋大学, 工学研究科, 准教授 (00527947)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | イオンチャネル / 光応答性DNA / 光制御 / DNA / 架橋体 / カリウムチャネル / 光刺激 |
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| Outline of Final Research Achievements |
Recently, we have focused on the relationship between clustering and dispersion of ion channels and its functions. In this study, we have controlled the distance between channels by using photoresponsive DNA as a crosslinking agent for ion channels. By designing DNA with an appropriate sequence, we succeeded in controlling the distance between channels at room temperature.
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Report
(3 results)
Research Products
(7 results)
