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Constructing a system to prevent hepatitis B virus reactivation using a systematic error proofing method

Research Project

Project/Area Number 16K15309
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical sociology
Research InstitutionNara Medical University

Principal Investigator

Yamazaki Masaharu  奈良県立医科大学, 医学部, 病院教授 (60360054)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
KeywordsB型肝炎再活性化 / エラープルーフ法 / 階層分析 / B型肝炎 / 再活性化 / アンケート調査 / ガイドライン / エラープルーフ / 信頼性工学
Outline of Final Research Achievements

Severe hepatitis associated with HBV reactivation has not been eradicated despite clinical sites commonly following screening procedures for HBV infection. We examined a countermeasure against HBV reactivation using a systematic error-proofing method. This approach was found to be useful for detecting potential errors in the process and generated 47 high-grade solutions. In addition, we examined whether the process was influenced by physician and/or patient background using questionnaire responses from 140 physicians in an analytic hierarchy process. The results revealed differences in awareness of the importance of the process by physicians according to field of specialty, years of experience and knowledge about HBV reactivation. Also, physicians active in the process tended to place importance on the administration of drugs that cause HBV reactivation, while physicians not active in the process were apt to ignore this issue, particularly if the patient showed poor prognosis.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (5 results)

All 2017 2016

All Journal Article (2 results) (of which Open Access: 1 results) Presentation (3 results)

  • [Journal Article] 系統的エラープルーフ化プロセスを用いたB型肝炎再活性化対策立案の試み2017

    • Author(s)
      山崎正晴
    • Journal Title

      臨床病理

      Volume: 65 補冊 Pages: 207-207

    • Related Report
      2017 Annual Research Report
  • [Journal Article] B型肝炎ウイルス再活性化対策を通じた多職種連携について2016

    • Author(s)
      山崎 正晴
    • Journal Title

      臨床病理

      Volume: 64 Pages: 1085-1090

    • Related Report
      2016 Research-status Report
    • Open Access
  • [Presentation] 系統的エラープルーフ化プロセスを用いたB型肝炎再活性化対策立案の試み2017

    • Author(s)
      山崎正晴
    • Organizer
      第64回日本臨床検査医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 院内アラートメールによるB型肝炎再活性化対策の効果2016

    • Author(s)
      山崎 正晴
    • Organizer
      第63回日本臨床検査医学会学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2016-09-01
    • Related Report
      2016 Research-status Report
  • [Presentation] B型肝炎ウイルス再活性化対策を通じた多職種連携について2016

    • Author(s)
      山崎 正晴
    • Organizer
      日本臨床検査医学会第59回近畿支部総会
    • Place of Presentation
      和歌山県JAビル(和歌山県和歌山市)
    • Year and Date
      2016-05-14
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2019-03-29  

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