| Project/Area Number |
16K15458
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
大橋 圭明 岡山大学, 大学病院, 講師 (60729193)
久保 寿夫 岡山大学, 大学病院, 助教 (90726928)
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| Research Collaborator |
HIGO Hisao 岡山大学, 大学院医師薬学総合研究科, 大学院生
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 肺線維症 / 特発性肺線維症 / 次世代シーケンサー / Kinase遺伝子発現解析 / レーザーマイクロダイセクション / 臨床呼吸器学 |
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| Outline of Final Research Achievements |
We performed comprehensive analysis in plumonary fibrosis to develop precision medicine. We obtained 13 samples from 5 patients. 6 samples were from bilateral pneumotectomy. The gene expression profile was heterogeneous even in same patient. ERBB4 or PIM2 was overexpressed in some of our cases. These genes might be possible druggable target for pulmonary fibrosis.
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