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Characteristics of brain auditory information processing and ADHD-like symptom.

Research Project

Project/Area Number 16K15555
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionKanazawa University

Principal Investigator

Kikuchi Mitsuru  金沢大学, 子どものこころの発達研究センター, 教授 (00377384)

Co-Investigator(Kenkyū-buntansha) 林 則夫  群馬県立県民健康科学大学, 診療放射線学部, 准教授 (50648459)
Research Collaborator Yoshimura Yuko  
Hasegawa Chiaki  
Takahashi Tetsuya  
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords注意欠陥多動性障害 / 脳磁図 / 幼児 / 聴覚誘発反応 / 同調性 / 脳機能 / 脳磁図計 / 聴覚
Outline of Final Research Achievements

The aim of this research is to investigate a novel sprout model that "atypicality of auditory information processing affects development". We researched on children with autism with ADHD symptoms. The synchronicity of the auditory evoked responses (P1m) in left and right hemispheres induced by speech stimulation was measured with an child-sized MEG system. We investigated the relationship between this brain functional synchronicity and the behavioral ability to be kept still. In children who cannot stay still, it was found that the synchronicity of the P1m in left and right hemispheres are low. This study revealed that the characteristics of auditory information processing are related to ADHD-like symptoms.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (21 results)

All 2017 2016 Other

All Int'l Joint Research (1 results) Journal Article (7 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 7 results,  Open Access: 5 results) Presentation (9 results) (of which Int'l Joint Research: 5 results,  Invited: 2 results) Remarks (4 results)

  • [Int'l Joint Research] モントリオール大学(カナダ)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Altered human voice processing in the frontal cortex and a developmental language delay in 3- to 5-year-old children with autism spectrum disorder2017

    • Author(s)
      Yoshimura Yuko、Kikuchi Mitsuru、Hayashi Norio、Hiraishi Hirotoshi、Hasegawa Chiaki、Takahashi Tetsuya、Oi Manabu、Remijn Gerard B.、Ikeda Takashi、Saito Daisuke N.、Kumazaki Hirokazu、Minabe Yoshio
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 17116-17116

    • DOI

      10.1038/s41598-017-17058-x

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Band-specific atypical functional connectivity pattern in childhood autism spectrum disorder.2017

    • Author(s)
      Takahashi T, Yamanishi T, Nobukawa S, Kasakawa S, Yoshimura Y, Hiraishi H, Hasegawa C, Ikeda T, Hirosawa T, Munesue T, Higashida H, Minabe Y, Kikuchi M.
    • Journal Title

      Clin Neurophysiol.

      Volume: 128 Issue: 8 Pages: 45-50

    • DOI

      10.1016/j.clinph.2017.05.010

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Near-Infrared Spectroscopy Study on Cortical Hemodynamic Responses to Normal and Whispered Speech in 3- to 7-Year-Old Children.2017

    • Author(s)
      Remijn GB, Kikuchi M, Yoshimura Y, Shitamichi K, Ueno S, Tsubokawa T, Kojima H, Higashida H, Minabe Y.
    • Journal Title

      J Speech Lang Hear Res.

      Volume: 1 Issue: 2 Pages: 465-470

    • DOI

      10.1044/2016_jslhr-h-15-0435

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mu rhythm suppression reflects mother-child face-to-face interactions: a pilot study with simultaneous MEG recording2016

    • Author(s)
      Hasegawa C, Ikeda T, Yoshimura Y, Hiraishi H, Takahashi T, Furutani N, Hayashi N, Minabe Y, Hirata M, Asada M, Kikuchi M
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 34977-34977

    • DOI

      10.1038/srep34977

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Contribution of Increased Gamma Band Connectivity to Visual Non-Verbal Reasoning in Autistic Children: A MEG Study.2016

    • Author(s)
      Takesaki N, Kikuchi M, Yoshimura Y, Hiraishi H, Hasegawa C, Kaneda R, Nakatani H, Takahashi T, Mottron L, Minabe Y.
    • Journal Title

      PLoS One.

      Volume: 15 Issue: 9 Pages: e0163133-e0163133

    • DOI

      10.1371/journal.pone.0163133

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder.2016

    • Author(s)
      Yoshimura, Y., Kikuchi, M., Hiraishi, H., Hasegawa, C., Takahashi, T., Remijn, G.B., Oi, M., Munesue, T., Higashida, H., & Minabe, Y.
    • Journal Title

      NeuroImage: Clinical

      Volume: 12 Pages: 300-305

    • DOI

      10.1016/j.nicl.2016.07.009

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Atypical Bilateral Brain Synchronization in the Early Stage of Human Voice Auditory Processing in Young Children with Autism.2016

    • Author(s)
      Kurita T, Kikuchi M, Yoshimura Y, Hiraishi H, Hasegawa C, Takahashi T, Hirosawa T, Furutani N, Higashida H, Ikeda T, Mutou K, Asada M, Minabe Y.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 4 Pages: 0153077-0153077

    • DOI

      10.1371/journal.pone.0153077

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Atypical development of the central auditory system in young children with Autism spectrum disorder.2017

    • Author(s)
      Mitsuru Kikuchi, Yoshio Minabe
    • Organizer
      CCD-KITMEGWorkshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of the central auditory system in typically developing young children and children with Autism spectrum disorder.2017

    • Author(s)
      Mitsuru Kikuchi, Yuko Yoshimura, Yoshio Minabe
    • Organizer
      Biomagnetic Sendai 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 幼児用MEGをもちいた幼児脳機能の分析2017

    • Author(s)
      Mitsuru Kikuchi, Yoshio Minabe
    • Organizer
      5th INCF Japan Node International Workshop Advances in Neuroinformatics AINI 2017 New Approaches to Neuroinformatics Education
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 自閉症幼児期における最近のMEG研究2017

    • Author(s)
      菊知 充
    • Organizer
      第133回日本精神神経学会学術総会 教育講演
    • Related Report
      2017 Annual Research Report
  • [Presentation] 自閉スペクトラム症のMEG研究2017

    • Author(s)
      菊知 充
    • Organizer
      第29回 小児脳機能研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Atypical development of the auditory system in children with autism spectrum disorder2016

    • Author(s)
      Mitsuru Kikuchi,Yoshio Minabe
    • Organizer
      The 20th International Conference on Biomagnetism (BIOMAG2016)
    • Place of Presentation
      Seoul (Korea)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Atypical brain activity in children with autism spectrum disorder2016

    • Author(s)
      Mitsuru Kikuchi
    • Organizer
      The 3rd International Symposium on Cognitive Neuroscience Robotics: Toward Constructive Developmental Science
    • Place of Presentation
      Osaka (Japan)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Atypical development of the auditory system in children with autism: custom child-sized MEG studies2016

    • Author(s)
      菊知 充
    • Organizer
      第55回日本生体医工学会大会 (富山国際会議場)
    • Place of Presentation
      富山国際会議場(富山市)
    • Related Report
      2016 Research-status Report
  • [Presentation] 自閉症幼児期のMEG研究2016

    • Author(s)
      菊知 充 三邉義雄
    • Organizer
      第31回日本生体磁気学会大会
    • Place of Presentation
      金沢市文化ホール(金沢市)
    • Related Report
      2016 Research-status Report
  • [Remarks] バンビプラン

    • URL

      http://bambiplan.w3.kanazawa-u.ac.jp/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 子どものこころの発達研究センター

    • URL

      https://kodomokokoro.w3.kanazawa-u.ac.jp/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 金沢大学子どものこころの発達研究センター

    • URL

      https://kodomokokoro.w3.kanazawa-u.ac.jp/

    • Related Report
      2016 Research-status Report
  • [Remarks] 金沢大学バンビプラン

    • URL

      http://bambiplan.w3.kanazawa-u.ac.jp/

    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2019-03-29  

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