Construction of treatment-resistant depression model mice concurrent with alcohol dependence

• Project/Area Number: 16K15565
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Psychiatric science
• Research Institution: Tokyo Metropolitan Institute of Medical Science
• Principal Investigator: IKEDA Kazutaka 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 分野長 (60281656)
• Co-Investigator(Kenkyū-buntansha): 井手 聡一郎 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員 (30389118) ; 藤田 雅代 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員 (90415539)
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 難治性うつ病 / アルコール依存 / 難治性気分障害 / ケタミン / 抗うつ薬 / モデル動物 / GluN2D / NMDA受容体 / 医療・福祉 / 神経科学 / 生理活性 / 脳・神経 / 薬理学

Outline of Final Research Achievements

We constructed the treatment-resistant depression model mice concurrent with alcohol dependence which does not ameliorate with fluoxetine continuous treatment but ameliorates with ketamine single dose in both the sucrose preference test and the novelty suppressed feeding test. Furthermore, in studies using GluN2D-knockout mice, we revealed that GluN2D could play an important role in the sustained antidepressant effect and cognitive impairment observed after single administration of R-ketamine.

Academic Significance and Societal Importance of the Research Achievements

アルコール依存症とうつ病は合併頻度が高く、既存の抗うつ薬では治療効果が低いことから、合併患者における発症メカニズム解明と治療法の開発が求められているものの、動物モデルを用いたアルコール依存併発の難治性うつ病研究は殆ど行われていなかった。本研究成果は、難治性うつ病治療に有用であるとされるケタミンの作用機序解明に繋がる知見を提唱するとともに、アルコール依存併発の難治性うつ病モデルマウスを新たに構築することで新規創薬・治療法開発に有用なツールを提供する。

Research Products

• [Journal Article] Study of effects of ifenprodil in patients with methamphetamine dependence: Protocol for an exploratory, randomized, double-blind, placebo-controlled trial. (2019)
  • Author(s): Kotajima-Murakami H, Takano A, Ogai Y, Tsukamoto S, Murakami M, Funada D, Tanibuchi Y, Tachimori H, Maruo K, Sasaki T, Matsumoto T, Ikeda K.
  • Journal Title: Neuropsychopharmacology Reports. Volume: － Issue: 2 Pages: 1-10
  • DOI: 10.1002/npr2.12050
  • Peer Reviewed / Open Access
• [Journal Article] Three-dimensional alteration of neurites in schizophrenia. (2019)
  • Author(s): Mizutani R, Saiga R, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, De Andrade V, De Carlo F, Takekoshi S, Inomoto C, Nakamura N, Kushima I, Iritani S, Ozaki N, Ide S, Ikeda K, Oshima K, Itokawa M, Arai M.
  • Journal Title: Transl Psychiatry. Volume: 9 Issue: 1 Pages: 1-12
  • DOI: 10.1038/s41398-019-0427-4
  • NAID: 40022096063
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effects of rapamycin on social interaction deficits and gene expression in mice exposed to valproic acid in utero. (2019)
  • Author(s): Kotajima-Murakami H, Kobayashi T, Kashii H, Sato A, Hagino Y, Tanaka M, Nishito Y, Takamatsu Y, Uchino S, Ikeda K.
  • Journal Title: Mol Brain Volume: 12 Issue: 1 Pages: 3-3
  • DOI: 10.1186/s13041-018-0423-2
  • Peer Reviewed / Open Access
• [Journal Article] Opioid and non-dopamine reward circuitry and state-dependent mechanisms. (2018)
  • Author(s): Fujita M, Ide S, Ikeda K
  • Journal Title: Ann NY Acad Sci Volume: 印刷中 Issue: 1 Pages: 29-41
  • DOI: 10.1111/nyas.13605
  • Peer Reviewed
• [Journal Article] Resistin is a novel marker for postoperative pain intensity. (2018)
  • Author(s): Hozumi J, Sumitani M, Nishizawa D, Nagashima M, Ikeda K, Abe H, Kato R, Kusakabe Y, Yamada Y, Japanese TR-Cancer Pain research Group
  • Journal Title: Anesth Analg Volume: 印刷中 Issue: 3 Pages: 563-568
  • DOI: 10.1213/ane.0000000000003363
  • Peer Reviewed
• [Journal Article] Brain hyperserotonemia causes autism-relevant social deficits in mice. (2018)
  • Author(s): Tanaka M, Sato A, Kasai S, Hagino Y, Kotajima-Murakami H, Kashii H, Takamatsu Y, Nishito Y, Inagaki M, Mizuguchi M, Hall FS, Uhl GR, Murphy D, Sora I, Ikeda K.
  • Journal Title: Mol Autism Volume: 9 Issue: 1 Pages: 60-60
  • DOI: 10.1186/s13229-018-0243-3
  • NAID: 120006543336
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gamma-aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: an exploratory study (2018)
  • Author(s): Yokoshima Y, Sumitani M, Nishizawa D, Nagashima M, Ikeda K, Kato R, Hozumi J, Abe H, Azuma K, Tsuchida R, Yamada Y, Japanese TR-Cancer Pain research Group
  • Journal Title: Neuropsychopharmacol Rep Volume: 38(4) Issue: 4 Pages: 175-181
  • DOI: 10.1002/npr2.12030
  • Peer Reviewed / Open Access
• [Journal Article] Reward-enhancing effect of methylphenidate is abolished in dopamine transporter knockout mice: A model of attention-deficit/hyperactivity disorder (2018)
  • Author(s): Ide Soichiro、Ikekubo Yuiko、Hua Jennifer、Takamatsu Yukio、Uhl George R.、Sora Ichiro、Ikeda Kazutaka
  • Journal Title: Neuropsychopharmacology Reports Volume: 38 Issue: 3 Pages: 149-153
  • DOI: 10.1002/npr2.12020
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Initial severity of major depression and efficacy of new generation antidepressants: Individual-participant data meta-analysis (2018)
  • Author(s): Furukawa TA, Maruo K, Noma H, Tanaka S, Imai H, Shinohara K, Ikeda K, Yamawaki S, Levine SZ, Goldberg Y, Leucht S & Cipriani A
  • Journal Title: Acta Psychiatrica Scandinavica Volume: epub Issue: 6 Pages: 1-8
  • DOI: 10.1111/acps.12886
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Early manifestation of depressive-like behavior in transgenic mice that express dementia with Lewy bodies-linked mutant beta-synuclein. (2018)
  • Author(s): Fujita M, Hagino Y, Takamatsu Y, Shimizu Y, Takamatsu Y, Ikeda K, Hashimoto M
  • Journal Title: Neuropsychopharmacology Rep Volume: 印刷中 Issue: 2 Pages: 95-97
  • DOI: 10.1002/npr2.12009
  • Peer Reviewed / Open Access
• [Journal Article] Association between the rs7583431 single-nucleotide polymorphism close to the activating transcription factor 2 (ATF2) gene and the analgesic effect of fentanyl in the cold pain test. (2018)
  • Author(s): Aoki Y, Nishizawa D, Yoshida K, Hasegawa J, Kasai S, Takahashi K, Koukita Y, Ichinohe T, Hayashida M, Fukuda K, Ikeda K
  • Journal Title: Neuropsychopharmacology Rep Volume: 印刷中 Issue: 2 Pages: 86-91
  • DOI: 10.1002/npr2.12012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association between rs2275913 single-nucleotide polymorphism of the interleukin-17A gene and perioperative analgesic use in cosmetic orthognathic surgery (2018)
  • Author(s): Ohka Seii、Nishizawa Daisuke、Hasegawa Junko、Takahashi Kaori、Nakayama Kyoko、Ebata Yuko、Fukuda Ken-ichi、Ikeda Kazutaka
  • Journal Title: Neuropsychopharmacology Reports Volume: e12010 Issue: 2 Pages: 67-74
  • DOI: 10.1002/npr2.12010
  • Peer Reviewed / Open Access
• [Journal Article] Association between N-methyl-D-aspartate receptor subunit 2B gene polymorphisms and personality traits in a young Japanese population. (2018)
  • Author(s): Narita S, Onozawa Y, Yoshihara E, Nishizawa D, Numajiri M, Ikeda K, Iwahashi K
  • Journal Title: East Asian Arch Psychiatry Volume: 28 Pages: 45-52
  • DOI: 10.12809/eaap181712
  • Peer Reviewed / Open Access
• [Journal Article] Brain tissue fingerprints of schizophrenia and control individuals (2018)
  • Author(s): Mizutani R, Saiga R, Takeuchi A, Uesugi K, Terada Y, Suzuki Y, Andrade VD, Carlo FD, Takekoshi S, Inomoto C, Nakamura N, Kushima I, Iritani S, Ozaki N, Ide S, Ikeda K, Oshima K, Itokawa M, Arai M
  • Journal Title: Neurons and Cognition (q-bio.NC); Biological Physics (physics.bio-ph) Volume: arXiv
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mechanisms of the Antidepressant Effects of Ketamine Enantiomers and Their Metabolites (2018)
  • Author(s): Ide Soichiro、Ikeda Kazutaka
  • Journal Title: Biological Psychiatry Volume: 84 Issue: 8 Pages: 551-552
  • DOI: 10.1016/j.biopsych.2018.07.018
  • Peer Reviewed
• [Journal Article] 薬物依存 (2018)
  • Author(s): 井手聡一郎, 池田和隆
  • Journal Title: Clinical Neuroscience Volume: 36 Pages: 732-735
• [Journal Article] Association between N-methyl-D-aspartate receptor 2B subunit gene polymorphisms and personality traits in a young Japanese population. (2018)
  • Author(s): Narita S, Yoshihara E, Nishizawa D, Numajiri M, Onozawa Y, Ikeda K, Iwahashi K
  • Journal Title: East Asian Arch Psychiatry Volume: 印刷中
  • Peer Reviewed
• [Journal Article] A randomized controlled study of the effect of ifenprodil on alcohol use in patients with alcohol dependence. (2018)
  • Author(s): *Sugaya, N., *Ogai, Y.(*equal contribution), Aikawa, Y., Yumoto, Y., Takamaha, M., Tanaka, M., Haraguchi, A., Umeno, M., Ikeda, K.
  • Journal Title: Neuropsychopharmacology Reports. Volume: 38(1) Issue: 1 Pages: 9-17
  • DOI: 10.1002/npr2.12001
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide association study identifies polymorphisms associated with the analgesic effect of fentanyl in the preoperative cold pressor-induced pain test (2018)
  • Author(s): Takahashi K, Nishizawa D, Kasai S, Koukita Y, Fukuda K, Ichinohe T, Ikeda K
  • Journal Title: J Pharmacol Sci Volume: 136(3) Issue: 3 Pages: 107-113
  • DOI: 10.1016/j.jphs.2018.02.002
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genome-wide scan identifies candidate loci related to remifentanil requirements during laparoscopic-assisted colectomy. (2018)
  • Author(s): 2.Nishizawa D, Mieda T, Tsujita M, Nakagawa H, Yamaguchi S, Kasai S, Hasegawa J, Fukuda KI, Kitamura A, Hayashida M, Ikeda K.
  • Journal Title: Pharmacogenomics Volume: 19 Issue: 2 Pages: 113-127
  • DOI: 10.2217/pgs-2017-0109
  • Peer Reviewed
• [Journal Article] Association between polymorphisms in the purinergic P2Y12 receptor gene and severity of both cancer pain and postoperative pain (2018)
  • Author(s): Sumitani M, Nishizawa D, Nagashima M, Ikeda K, Abe H, Kato R, Ueda H, Yamada Y
  • Journal Title: Pain Med Volume: 19(2) Issue: 2 Pages: 348-354
  • DOI: 10.1093/pm/pnx102
  • Peer Reviewed
• [Journal Article] A pharmacogenetics approach to pain management. (2018)
  • Author(s): Yoshida K, Nishizawa D, Ide S, Ichinohe T, Fukuda K, Ikeda K
  • Journal Title: Neuropsychopharmacology Rep Volume: 38 Issue: 1 Pages: 2-8
  • DOI: 10.1002/npr2.12003
  • Peer Reviewed / Open Access
• [Journal Article] 創薬開発に向けた産官学連携―Public Private Partnerships, PPPs―. (2018)
  • Author(s): 池田和隆, 小居秀紀, 菊地哲朗, 森尾保徳, 川上善之, 須原哲也, 中込和幸, 山脇成人
  • Journal Title: 臨床精神医学 Volume: 47 Pages: 315-319
• [Journal Article] 薬剤選択に寄与する研究環境の整備. (2018)
  • Author(s): 中込和幸, 森尾保徳, 小居秀紀, 池田和隆, 山脇成人
  • Journal Title: 臨床精神薬理 Volume: 21 Pages: 155-161
• [Journal Article] 依存の神経・分子メカニズム解析のための動物モデル. (2018)
  • Author(s): 井手聡一郎, 池田和隆
  • Journal Title: 分子精神医学 Volume: 18(1) Pages: 15-21
• [Journal Article] Association between N-methyl-D-aspartate receptor subunit 2B gene polymorphisms and alcohol dependence in a Japanese population. (2017)
  • Author(s): Narita S, Yoshihara E, Nishizawa D, Kawai A, Ikeda K, Iwahashi K
  • Journal Title: 日本アルコール薬物医学会雑誌 Volume: 52(5) Pages: 156-167
  • NAID: 40021423809
  • Peer Reviewed
• [Journal Article] Role of NMDA receptor GluN2D subunit in the antidepressant effects of enantiomers of ketamine. (2017)
  • Author(s): Ide S, Ikekubo Y, Mishina M, Hashimoto K, Ikeda K
  • Journal Title: J Pharmacol Sci Volume: 135(3) Issue: 3 Pages: 138-140
  • DOI: 10.1016/j.jphs.2017.11.001
  • Peer Reviewed / Open Access
• [Journal Article] Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese (2017)
  • Author(s): Tanabe Y, Shimizu C, Hamada A, Hashimoto K, Ikeda K, Nishizawa D, Hasegawa J, Shimomura A, Ozaki Y, Tamura N, Yamamoto H, Yunokawa M, Yonemori K, Takano T, Kawabata H, Tamura K, Fujiwara Y
  • Journal Title: Cancer Chemother Pharmacol Volume: 79(6) Issue: 6 Pages: 1179-1186
  • DOI: 10.1007/s00280-017-3314-9
  • Peer Reviewed / Open Access
• [Journal Article] Light/dark phase-dependent spontaneous activity is maintained in dopamine-deficient mice. (2017)
  • Author(s): 3.Fujita M, Hagino Y, Takeda T, Kasai S, Tanaka M, Takamatsu Y, Kobayashi K, Ikeda K.
  • Journal Title: Mol Brain Volume: 10 Issue: 1 Pages: 49-49
  • DOI: 10.1186/s13041-017-0329-4
  • Peer Reviewed / Open Access
• [Journal Article] No association between the polymorphism rs6943555 in the AUTS2 gene and personality traits in Japanese university students (2017)
  • Author(s): Narita S, Ikeda K, Nishizawa D, Yoshihara E, Numajiri M, Onozawa Y, Ohtani N, Iwahashi K
  • Journal Title: Psychiatry Investigation Volume: 14(5) Issue: 5 Pages: 681-686
  • DOI: 10.4306/pi.2017.14.5.681
  • Peer Reviewed / Open Access
• [Journal Article] Opioid dose and neuropathic pain before and after electroconvulsive therapy (2017)
  • Author(s): Iwata K, Kobayashi Y, Mera H, Doi N, Suwa H, Ikeda K
  • Journal Title: Journal of Japan Society of Pain Clinicians Volume: 24 Issue: 2 Pages: 116-120
  • DOI: 10.11321/jjspc.16-0024
  • NAID: 130006832066
  • ISSN: 1340-4903, 1884-1791
  • Peer Reviewed / Open Access
• [Journal Article] ゲノムワイド関連解析を利用したオピオイドのテーラーメイド医療への試み. (2017)
  • Author(s): 三枝勉, 西澤大輔, 福田謙一, 池田和隆, 北村晶, 林田眞和
  • Journal Title: 麻酔・集中治療とテクノロジー2017 Volume: - Pages: 16-21
  • Open Access
• [Journal Article] JSNP Excellent Presentation Award for CINP2016: Association between autism susceptibility candidate 2 haplotypes and alcohol dependence in a Japanese population. (2017)
  • Author(s): Narita S, Iwahashi K, Yoshihara E, Kawai A, Nishizawa D, Ikeda K
  • Journal Title: 日本神経精神薬理学雑誌 Volume: 37(3) Pages: 97-98
• [Journal Article] JSNP Excellent Presentation Award for CINP2016: 注意欠如/ 多動性障害モデルマウスにおけるメチルフェニデートの報酬効果の変化. (2017)
  • Author(s): 井手聡一郎, 高松幸雄, 池窪結子, Takeda TC, Nagasawa S, Hua J, Uhl GR, 曽良一郎, 池田和隆
  • Journal Title: 日本神経精神薬理学雑誌 Volume: 37(2) Pages: 49-50
  • Int'l Joint Research
• [Journal Article] JSNP Excellent Presentation Award for CINP2016: ゲノムワイド関連解析 (GWAS) による腹腔鏡補助下大腸切除術後フェンタニル必要量に影響する遺伝子多型の同定. (2017)
  • Author(s): 西澤大輔, 三枝勉, 辻田美紀, 天野功二郎, 田代浄, 石井利昌, 山口茂樹, 笠井慎也, 長谷川準子, 池田和隆, 北村晶, 林田眞和
  • Journal Title: 日本神経精神薬理学雑誌 Volume: 37(2) Pages: 53-54
• [Journal Article] 遺伝子多型に基づいた個別鎮痛法の開発. (2017)
  • Author(s): 西澤大輔, 福田謙一, 林田眞和, 池田和隆
  • Journal Title: ペインクリニック Volume: 38
• [Journal Article] ペインクリニックにおける精密医療. (2017)
  • Author(s): 池田和隆
  • Journal Title: ペインクリニック Volume: 38 Pages: 557-558
  • Peer Reviewed
• [Journal Article] Association between polymorphisms in the purinergic P2Y12 receptor gene and severity of both cancer pain and postoperative pain. (2017)
  • Author(s): Sumitani M, Nishizawa D, Nagashima M, Ikeda K, Abe H, Kato R, Ueda H, Yamada Y
  • Journal Title: Pain Med Volume: 印刷中
  • Peer Reviewed
• [Journal Article] Distinct roles of opioid and dopamine systems in lateral hypothalamic intracranial self-stimulation. (2017)
  • Author(s): Ide S, Takahashi T, Takamatsu Y, Uhl G, Niki H, Sora I, Ikeda K
  • Journal Title: Int J Neuropsychopharmacol Volume: 印刷中 Pages: pyw113-pyw113
  • DOI: 10.1093/ijnp/pyw113
  • NAID: 120006373767
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT2C receptor dysfunction, and anhedonia in mice. (2017)
  • Author(s): Yamamoto H, Kamegaya E, Hagino Y, Takamatsu Y, Sawada W, Matsuzawa M, Ide S, Yamamoto T, Mishina M, Ikeda K
  • Journal Title: Neuropharmacology Volume: 112(Pt A) Pages: 188-197
  • DOI: 10.1016/j.neuropharm.2016.07.036
  • Peer Reviewed / Open Access
• [Journal Article] Association between UGT2B7 gene polymorphisms and fentanyl sensitivity in patients undergoing painful orthognathic surgery. (2016)
  • Author(s): Muraoka W, Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Wajima K, Nakagawa T, Ikeda K
  • Journal Title: Mol Pain Volume: 12 Pages: 1-12
  • DOI: 10.1177/1744806916683182
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Opposite associations between the rs3845446 single-nucleotide polymorphism of the CACNA1E gene and postoperative pain-related phenotypes in gastrointestinal surgery versus previously reported orthognathic surgery. (2016)
  • Author(s): Amano K, Nishizawa D, Mieda T, Tsujita M, Kitamura A, Hasegawa J, Inada E, Hayashida M, Ikeda K
  • Journal Title: J Pain Volume: 17(10) Issue: 10 Pages: 1126-1134
  • DOI: 10.1016/j.jpain.2016.07.001
  • Peer Reviewed
• [Journal Article] Nociceptin/orphanin FQ receptor gene variation is associated with smoking status in Japanese. (2016)
  • Author(s): Kasai S, Nishizawa D, Hasegawa J, Sato N, Tanioka F, Sugimura H, Ikeda K
  • Journal Title: Pharmacogenomics Volume: 17(13) Issue: 13 Pages: 1441-1451
  • DOI: 10.2217/pgs.15.184
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] オピオイド感受性遺伝子の個体差について. (2016)
  • Author(s): 西澤大輔, 福田謙一, 林田眞和, 池田和隆
  • Journal Title: Locomotive Pain Frontier Volume: 5(2) Pages: 14-18
  • NAID: 40021039483
• [Presentation] GIRK channels and NMDA receptor GluN2D subunit in signal pathways from addictive substances. (2019)
  • Author(s): Ikeda K
  • Organizer: FAOPS2019
  • Int'l Joint Research / Invited
• [Presentation] Personalized opioid use for overcoming opioid overdose problems. (2019)
  • Author(s): Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research / Invited
• [Presentation] Clinical study of GIRK channel inhibitors as candidate medicines for drug dependence. (2019)
  • Author(s): Ikeda K
  • Organizer: 第92回日本薬理学会年会
• [Presentation] Analysis of neuronal activity in hyperlocomotive dopamine-deficient mice. (2019)
  • Author(s): Ochiai Y, Fujita M, Takeda TC, Hagino Y, Kobayashi K, Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research
• [Presentation] Investigation of dopamine-deficient mice showing hyperactivity. (2019)
  • Author(s): Ochiai Y, Fujita M, Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research
• [Presentation] Transcriptome analyses in rodent models and postmortem human brains. (2019)
  • Author(s): Kasai S, Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research
• [Presentation] Associations between polymorphisms of the inflammation-related genes and analgesia or sensitivity to analgesics. (2019)
  • Author(s): Ohka S, Nishizawa D, Fukuda K, Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research
• [Presentation] Identification of genetic variations associated with human sensitivity to addictive substances and its clinical application. (2019)
  • Author(s): Nishizawa D, Ikeda K
  • Organizer: AsCNP-ASEAN2019
  • Int'l Joint Research
• [Presentation] 中枢薬の作用機序解明、開発、適正使用のための研究基盤：JSNPの活動を踏まえた今後の方向性. (2018)
  • Author(s): 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
  • Invited
• [Presentation] Tailor-made opioid analgesia based on genome-wide association study. (2018)
  • Author(s): Ikeda K
  • Organizer: 第15回国際歯科麻酔学会議（IFDAS2018）
  • Int'l Joint Research / Invited
• [Presentation] GIRK channels as common effectors in some pathways of alcohol and other addictive substances. (2018)
  • Author(s): Ikeda K
  • Organizer: 19th Congress of International Society for Biomedical Research on Alcoholism (ISBRA2018)
  • Int'l Joint Research / Invited
• [Presentation] 発達障害とモノアミン (2018)
  • Author(s): 池田和隆
  • Organizer: 第33回日本大脳基底核研究会
  • Invited
• [Presentation] 遺伝子多型からみたテーラーメード医療 (2018)
  • Author(s): 池田和隆, 西澤大輔, 林田眞和, 福田謙一
  • Organizer: 日本ペインクリニック学会 第52回大会
  • Invited
• [Presentation] Neuropsychiatric phenotypes in dopamine-deficient mice and dopamine transporter knockout mice. (2018)
  • Author(s): Ikeda K
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research / Invited
• [Presentation] NMDA receptor channel GluN2D subunit as a new target molecule for medicines for mental disorders. (2018)
  • Author(s): Ikeda K, Ide S
  • Organizer: 24th International Union of Biochemistry and Molecular Biology (IUBMB) Congress and 15th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Congress
  • Int'l Joint Research / Invited
• [Presentation] 遺伝子配列でわかる鎮痛薬感受性個人差 (2018)
  • Author(s): 池田和隆
  • Organizer: 第12回日本緩和医療薬学会年会
  • Invited
• [Presentation] 疼痛感受性と鎮痛薬感受性の遺伝要因解明とその臨床応用 (2018)
  • Author(s): 池田和隆
  • Organizer: 第61回日本糖尿病学会年次学術集会
  • Invited
• [Presentation] 腹腔鏡補助下大腸結腸切除術後鎮痛薬感受性ゲノムワイド網羅的多型解析で上位候補となった一塩基多型に関する外科的顎矯正術後鎮痛薬感受性との関連 (2018)
  • Author(s): 井上理恵, 西澤大輔, 長谷川準子, 中山京子, 福田謙一, 林田眞和, 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] STAT4遺伝子の一塩基多型rs6738544およびSTAT6遺伝子の一塩基多型rs2298170はニコチン依存と統計的に有意に関連する (2018)
  • Author(s): 大岡静衣, 西澤大輔, 長谷川準子, 佐藤直美, 山田英孝, 谷岡書彦, 椙村春彦, 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] NMDA受容体GluN2Dサブユニット欠損マウスにおける(R)-ケタミンの持続的抗うつ効果ならびに認知機能阻害効果の消失 (2018)
  • Author(s): 井手聡一郎, 池窪結子, 橋本謙二, 三品昌美, 池田和隆
  • Organizer: 28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] ドーパミン欠乏マウスを用いた各種自発行動のおけるドーパミン依存症の解析 (2018)
  • Author(s): 藤田雅代, 萩野洋子, 武田大志, 笠井慎也, 高松幸雄, 池田和隆
  • Organizer: 28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] ゲノムワイド関連解析(GWAS)による冷水誘発疼痛試験におけるフェンタニルの鎮痛効果と関連する遺伝子多型の同定 (2018)
  • Author(s): 西澤大輔, 髙橋香央里, 吉田香織, 笠井慎也, 長谷川準子, 中山京子, 江畑裕子, 高北義彦, 福田謙一, 一戸達也, 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] 覚せい剤依存症患者者におけるイフェンプロジルの効果検討とfMRIを基点としたバイオマーカーの開発：二重盲検無作為化比較試験(研究プロトコル) (2018)
  • Author(s): 古田島浩子, 高野歩, 大谷保和, 塚本正太郎, 村上真紀, 船田大輔, 谷渕由布子, 立森久照, 丸尾和司, 佐々木剛, 高橋英彦, 川人光男, 花川隆, 松本俊彦, 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] プロポフォール投与後の効果部位濃度におけるCYP2B6の遺伝子多型の影響 (2018)
  • Author(s): 髙橋香央里, 西澤大輔, 山田芳嗣, 笠井慎也, 須野学, 高北義彦, 一戸達也, 福田謙一, 池田和隆
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] mTOR阻害剤を使用中の結節性硬化症患者における自閉症症状の変化 (2018)
  • Author(s): 佐藤敦志, 池田和隆, 水口雅
  • Organizer: 第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会 合同年会
• [Presentation] Autistic-like behavioral deficits are severer in Tsc2 than Tsc1 haploinsufficiency in mouse models of TSC. (2018)
  • Author(s): Sato A, Tanaka M, Kashii H, Kotajima-Murakami H, Kasai S, Hagino Y, Kobayashi T, Hino O, Mizuguchi M, Ikeda K
  • Organizer: 国際TSCリサーチカンファレンス2018 (ITSCRC2018)
  • Int'l Joint Research
• [Presentation] How social deprivation differentially affects alcohol intake behavior among male and female mice?. (2018)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Ikeda K, Uhl GR, Sora I
  • Organizer: 19th Congress of International Society for Biomedical Research on Alcoholism (ISBRA2018)
  • Int'l Joint Research
• [Presentation] Psychological or physiological stress-induced alcohol consumption in mice lacking opioid receptors. (2018)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Ikeda K, Uhl GR, Sora I
  • Organizer: 19th Congress of International Society for Biomedical Research on Alcoholism (ISBRA2018)
  • Int'l Joint Research
• [Presentation] Identification of genetic polymorphisms associated with human sensitivity to addictive substances and its clinical application. (2018)
  • Author(s): Nishizawa D, Ikeda K
  • Organizer: 19th Congress of International Society for Biomedical Research on Alcoholism (ISBRA2018)
  • Int'l Joint Research
• [Presentation] Role of NMDA receptor GluN2D subunit in the antidepressant effects and the cognitive impairment effects on enantiomers of ketamine. (2018)
  • Author(s): Ide S, Ikekubo Y, Mishina M, Hashimoto K, Ikeda K
  • Organizer: 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
  • Int'l Joint Research
• [Presentation] The role of the serotonin 1B receptor system in the development of methamphetamine-induced sensitization. (2018)
  • Author(s): Moriya Y, Kasahara Y, Hagino Y, Hall FS, Hen R, Ikeda K, Uhl GR, Sora I
  • Organizer: IBNS 27th Annual Meeting
  • Int'l Joint Research
• [Presentation] Genome-wide association study identifies genetic polymorphisms associated with the analgesic effect of fentanyl in the preoperative cold pressor-induced pain test. (2018)
  • Author(s): Nishizawa D, Takahashi K, Yoshida K, Kasai S, Hasegawa J, Nakayama K, Ebata Y, Koukita Y, Fukuda K, Ichinohe T, Ikeda K
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research
• [Presentation] The long-lasting antidepressant effects and the cognitive impairment effects of (R)-ketamine are abolished in NMDA receptor GluN2D subunit knockout mice. (2018)
  • Author(s): Ide S, Ikekubo Y, Mishina M, Hashimoto K, Ikeda K
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research
• [Presentation] Rapamycin ameliorates impairment of social interaction in the mice exposed in utero to valproic acid. (2018)
  • Author(s): Murakami H, Kobayashi T, Kashii H, Sato A, Hagino Y, Tanaka M, Nishito Y, Takamatsu Y, Uchino S, Ikeda K
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research
• [Presentation] Gene expression profile of dopamine-deficient mouse brain for underlying molecular pathology in psychiatric disorders. (2018)
  • Author(s): Kasai S, Hagino Y, Fujita M, Kobayashi K, Ikeda K
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research
• [Presentation] rs6738544 SNP of STAT4 and rs2298170 SNP of STAT6 associate with nicotine dependence. (2018)
  • Author(s): Ohka S, Nishizawa D, Hasegawa J, Sato N, Yamada H, Tanioka F, Sugimura H, Ikeda
  • Organizer: 31st CINP World Congress
  • Int'l Joint Research
• [Presentation] The orexin (hypocretin) receptor 2 gene polymorphism Val308Ile associated with nicotine dependence. (2018)
  • Author(s): Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Ujike H, Hashimoto R, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Hayashida M, Sugimura H, Ikeda K
  • Organizer: 2018 NIDA International Forum
  • Int'l Joint Research
• [Presentation] Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence found in genome-wide and subsequent association studies. (2018)
  • Author(s): Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Ujike H, Hashimoto R, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Hayashida M, Sugimura H, Ikeda K
  • Organizer: CPDD 80th Annual Scientific Meeting
  • Int'l Joint Research
• [Presentation] 結節性硬化症モデルマウスの自閉症様行動に関わる遺伝子発現変化の解析 (2018)
  • Author(s): 柏井洋文, 佐藤敦志, 笠井慎也, 萩野洋子, 古田島浩子, 田中美歩, 小林敏之, 樋野興夫, 池田和隆, 岡明, 水口雅
  • Organizer: 第60回日本小児神経学会学術集会
• [Presentation] セロトニントランスポーター欠損マウスの自閉症様行動はトリプトファン欠乏食によって改善する (2018)
  • Author(s): 佐藤敦志, 田中美歩, 笠井慎也, 萩野洋子, 古田島浩子, 柏井洋文, 西藤泰昌, 稲垣真澄, 曽良一郎, 水口雅, 池田和隆
  • Organizer: 第60回日本小児神経学会学術集会
• [Presentation] Ketamine and NMDA receptor channels. (2018)
  • Author(s): Ikeda K
  • Organizer: TSBPN 2018 Spring Meeting
  • Int'l Joint Research / Invited
• [Presentation] Rapamycin treatment ameliorates impairment of social interaction in the mice treated prenatally with valproic acid. (2018)
  • Author(s): Kotajima H, Kobayashi T, Kashii H, Sato A, Hagino Y, Tanaka M, Nishito Y, Takamatsu Y, Uchino S, Ikeda K
  • Organizer: 第8回 新潟大学脳研究所共同研究拠点国際シンポジウム
• [Presentation] Gene expression profile corresponding to autism-like behaviors in mouse models of tuberous sclerosis complex. (2018)
  • Author(s): Kashii H, Kasai S, Hagino Y, Sato A, Kotajima H, Tanaka M, Kobayashi T, Hino O, Oka A, Mizuguchi M, Ikeda K
  • Organizer: 第8回 新潟大学脳研究所共同研究拠点国際シンポジウム
• [Presentation] The relationship between stress and alcohol consumption in female mice. (2017)
  • Author(s): Moriya Y, Kasahara Y, Hall SF, Uhl GR, Ikeda K, Sora I
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Place of Presentation: Nusa Dua, Indonesia
  • Year and Date: 2017-04-28
  • Int'l Joint Research
• [Presentation] Genome-wide association study of pain sensitivity in cold pressor test. (2017)
  • Author(s): Takahashi K, Fukuda K, Nishizawa D, Kasai S, Kokita Y, Ichinohe T, Ikeda K
  • Organizer: 2017 IADR(International Association for Dental Research)General Session & Exhibition
  • Place of Presentation: San Francisco, California, USA
  • Year and Date: 2017-03-23
  • Int'l Joint Research
• [Presentation] The rewarding effect of methylphenidate on attention deficit/hyperactivity disorder model mice. (2017)
  • Author(s): Ikekubo Y, Ide S, Takamatsu Y, Takeda TC, Nagasawa S, Hua J, Ikeda K
  • Organizer: 第90回日本薬理学会年会
  • Place of Presentation: 長崎ブリックホール・長崎新聞文化ホール（長崎県長崎市）
  • Year and Date: 2017-03-16
• [Presentation] 薬物感受性及び疾患脆弱性に関する全ゲノム関連解析結果データベースからのデータ抽出支援. (2017)
  • Author(s): 西澤大輔, 福田謙一, 林田眞和, 椙村春彦, 清水千佳子, 田中雅嗣, 池田和隆
  • Organizer: 平成28年度新学術領域研究 学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
  • Place of Presentation: 琵琶湖ホテル（滋賀県大津市）
  • Year and Date: 2017-02-07
• [Presentation] 注意欠如/ 多動性障害モデルマウスとしてのドパミントランスポーターノックアウトマウスの有用性. (2017)
  • Author(s): 井手聡一郎, 高松幸雄, 池窪結子, Takeda TC, Nagasawa S, Hua J, Uhl GR, 曽良一郎, 池田和隆
  • Organizer: 平成28年度新学術領域研究 学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
  • Place of Presentation: 琵琶湖ホテル（滋賀県大津市）
  • Year and Date: 2017-02-07
• [Presentation] 生理機能解析支援～薬理学的解析支援～. (2017)
  • Author(s): 森屋由紀, 西澤大輔, 井手聡一郎, 池田和隆
  • Organizer: 平成28年度新学術領域研究 学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
  • Place of Presentation: 琵琶湖ホテル（滋賀県大津市）
  • Year and Date: 2017-02-07
• [Presentation] 精神疾患病態におけるドーパミンシグナル関連マイクロエンドフェノタイプの解明. (2017)
  • Author(s): 池田和隆
  • Organizer: 新学術領域「マイクロ精神病態」班会議
  • Place of Presentation: 月岡ニューホテル冠月（新潟県新発田市）
  • Year and Date: 2017-01-22
• [Presentation] 次世代型薬物依存研究：神経ペプチド神経系の理解. (2017)
  • Author(s): 池田和隆
  • Organizer: 第52回日本アルコール・アディクション医学会学術総会
  • Invited
• [Presentation] Transcriptome profiling of dopamine-deficient mouse brain. (2017)
  • Author(s): Kasai S, Hagino Y, Fujita M, Kobayashi K, Ikeda K
  • Organizer: 第60回日本神経化学会大会
  • Invited
• [Presentation] 鎮痛薬適量予測式の構築と臨床応用技術の開発. (2017)
  • Author(s): 池田和隆
  • Organizer: 第４回包括的緩和医療科学学術研究会/第５回Tokyo疼痛緩和次世代研究会 合同研究会
  • Invited
• [Presentation] 疼痛緩和における“テーラーメイド治療”の実現に向けて. (2017)
  • Author(s): 井手聡一郎, 髙橋香央里, 西澤大輔, 福田謙一, 池田和隆
  • Organizer: 第11回日本緩和医療薬学会年会
  • Invited
• [Presentation] Molecular mechanisms underlying individual differences in pain and analgesic sensitivity. (2017)
  • Author(s): Kasai S, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research / Invited
• [Presentation] The involvement of acetylcholine system in hyperactivity in dopamine-deficient (DD) mice. (2017)
  • Author(s): Ikeda K, Fujita M, Hagino Y, Kobayashi K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research / Invited
• [Presentation] NMDA receptor channel subunit GluN2D: A dark horse molecule in Neuropsychopharmacology. (2017)
  • Author(s): Ikeda K, Hagino Y, Ide S
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research / Invited
• [Presentation] mTOR阻害剤投与による胎生期バルプロ酸曝露マウスの自閉症様行動への影響. (2017)
  • Author(s): 村上浩子, 小林敏之, 柏井洋文, 佐藤敦志, 萩野洋子, 田中美歩, 西藤泰昌, 高松幸雄, 内野茂夫, 池田和隆
  • Organizer: 2017年度生命科学系学会合同年次大会
• [Presentation] Circadian rhythm is maintained in dopamine-deficient mice. (2017)
  • Author(s): Fujita M, Hagino Y, Takeda TC, Kasai S, Tanaka M, Takamatsu Y, Kobayashi K, Ikeda K
  • Organizer: The 56th Annual Meeting of the American College of Neuropsychopharmacology (ACNP 56th Annual Meeting)
  • Int'l Joint Research
• [Presentation] ゲノムワイド関連解析（GWAS）による慢性疼痛感受性遺伝子多型の同定. (2017)
  • Author(s): 西澤大輔, 有田英子, 花岡一雄, 矢島直, 井関雅子, 加藤実, 小川節郎, 森山彩子, 笠井慎也, 長谷川準子, 林田眞和, 池田和隆
  • Organizer: 日本人類遺伝学会 第62回大会
• [Presentation] Sex differences in drinking behavior following stress in mu-opioid receptor knockout mice. (2017)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Hagino Y, Uhl GR, Ikeda K, Sora I
  • Organizer: Society for Neuroscience 2017
  • Int'l Joint Research
• [Presentation] TANDに対するmTOR阻害剤の自覚的改善効果. (2017)
  • Author(s): 佐藤敦志, 池田和隆, 水口雅
  • Organizer: 第5回日本結節性硬化症学会学術総会
• [Presentation] Genome-wide association study identifies candidate loci associated with intraoperative remifentanil requirements during laparoscopic-assisted celectomy. (2017)
  • Author(s): Nishizawa D, Mieda T, Tsujita M, Nakagawa H, Yamaguchi S, Kasai S, Hasegawa J, Fukuda K, Kitamura A, Hayashida M, Ikeda K
  • Organizer: ASHG2017 第67回米国人類遺伝学会
  • Int'l Joint Research
• [Presentation] 結節性硬化症モデルマウスにおける幼若期NMDA投与による点頭様発作の解析. (2017)
  • Author(s): 柏井洋文, 笠井慎也, 萩野洋子, 佐藤敦志, 古田島浩子, 田中美歩, 小林敏之, 樋野興夫, 岡明, 水口雅, 池田和隆
  • Organizer: 第51回日本てんかん学会年次学術集会
• [Presentation] インターロイキン-17A の一塩基多型と痛み関連表現型との関連解析. (2017)
  • Author(s): 大岡静衣, 西澤大輔, 長谷川準子, 高橋香央里, 中山京子, 江畑裕子, 福田謙一, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] ケタミンの抗うつ作用と認知機能障害におけるNMDA受容体GluN2Dサブユニットの役割. (2017)
  • Author(s): 井手聡一郎, 池窪結子, 橋本謙二, 三品昌美, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] muオピオイド受容体欠損マウスにおけるストレスとアルコール嗜好性に対する雌雄差の解析. (2017)
  • Author(s): 森屋由紀, 笠原好之, 萩野洋子, 池田和隆, 曽良一郎
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] 日本人における N-methyl-D-aspartate receptor 2B subunit 遺伝子多型とアルコール依存症との関連研究. (2017)
  • Author(s): 成田心, 吉原英児, 西澤大輔, 川合厚子, 池田和隆, 岩橋和彦
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] ゲノムワイド関連解析（GWAS）による腹腔鏡補助下大腸切除術中レミフェンタニル投与速度に影響する遺伝子多型の同定. (2017)
  • Author(s): 西澤大輔, 三枝勉, 辻田美紀, 山口茂樹, 笠井慎也, 長谷川準子, 福田謙一, 北村晶, 林田眞和, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] 胎生期バルプロ酸曝露マウスの社会性行動障害のラパマイシン投与による改善. (2017)
  • Author(s): 古田島（村上）浩子, 小林敏之, 柏井洋文, 佐藤敦志, 萩野洋子, 田中美歩, 西藤泰昌, 高松幸雄, 内野茂夫, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] Weaver変異型マウスにおける methamphetamineの報酬効果消失. (2017)
  • Author(s): 池窪結子, 井手聡一郎, 高松幸雄, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] Tsc2 ヘテロ欠損マウスの自閉症様行動に対するrapamycinの継続投与の効果とその副作用の検討. (2017)
  • Author(s): 柏井洋文, 笠井慎也, 萩野洋子, 佐藤敦志, 古田島浩子, 田中美歩, 小林敏之, 樋野興夫, 水口雅, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] セロトニントランスポーターノックアウトおよびヘテロ欠損マウスにおける自閉症様行動とトリプトファン欠乏食による改善効果. (2017)
  • Author(s): 田中美歩, 佐藤敦志, 笠井慎也, 萩野洋子, 古田島浩子, 柏井洋文, 西藤泰昌, 稲垣真澄, 曽良一郎, 池田和隆
  • Organizer: 第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
• [Presentation] 各種自発行動におけるドーパミン依存性の解析. (2017)
  • Author(s): 藤田雅代, 萩野洋子, Takeda T, 笠井慎也, 高松幸雄, 池田和隆
  • Organizer: 第52回日本アルコール・アディクション医学会学術総会
• [Presentation] 外側視床下部脳内自己刺激におけるオピオイド神経系とドパミン神経系の役割. (2017)
  • Author(s): 井手聡一郎, 高橋雄大, 高松幸雄, Uhl GR, 曽良一郎, 池田和隆
  • Organizer: 第37回鎮痛薬・オピオイドペプチドシンポジウム
• [Presentation] Association study of a candidate genetic variant with the development of taxane-induced peripheral neuropathy. (2017)
  • Author(s): Tanabe Y, Nishizawa D, Hasegawa J, Ikeda K, Shimomura A, Takano T, Shimizu C
  • Organizer: 第15回日本臨床腫瘍学会学術集会
• [Presentation] The effects of chronic stress on alcohol consumption in mu-opioid receptor knockout mice. (2017)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Uhl GR, Ikeda K, Sora I
  • Organizer: International Narcotics Research Conference 2017 (INRC2017)
  • Int'l Joint Research
• [Presentation] Stress-induced alcohol drinking in mice lacking mu-opioid receptors. (2017)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Uhl GR, Ikeda K, Sora I
  • Organizer: 26th Annual Meeting of the International Behavioral Neuroscience Society (IBNS2017)
  • Int'l Joint Research
• [Presentation] 遺伝子多型と疼痛感受性・オピオイド感受性. (2017)
  • Author(s): 林田眞和, 福田謙一, 西澤大輔, 池田和隆
  • Organizer: 日本麻酔科学会第64回学術集会
• [Presentation] Inhibition of mTOR improves autism-like behaviors in mice in utero exposed to valproic acid. (2017)
  • Author(s): Kotajima-Murakami H, Kobayashi T, Kashii H, Sato A, Hagino Y, Nishito Y, Takamatsu Y, Uchino S, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Rapamycin treatment of impaired social behavior in adolescent Tsc2+/－mice. (2017)
  • Author(s): Kashii H, Hagino Y, Kasai S, Kotajima H, Sato A, Kobayashi T, Hino O, Mizuguchi M, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Association between genetic polymorphisms in Cav2.3 (R-type) Ca2+ channels and fentanyl sensitivity in patients undergoing painful cosmetic surgery. (2017)
  • Author(s): Ide S, Nishizawa D, Fukuda K, Kasai S, Hasegawa J, Hayashida M, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Associations between polymorphisms close to the cAMP responsive element binding protein 1 (CREB1) gene and the activating transcription factor 2 (ATF2) gene and fentanyl sensitivity. (2017)
  • Author(s): Aoki Y, Nishizawa D, Yoshida K, Hasegawa J, Kasai S, Takahashi K, Koukita Y, Ichinohe T, Hayashida M, Fukuda K, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Single nucleotide polymorphisms in the 5’flanking region of interleukin-17A gene significantly associate with pain sensitivity. (2017)
  • Author(s): Ohka S, Nishizawa D, Hasegawa J, Takahashi K, Nakayama K, Ebata Y, Fukuda K, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Genetic polymorphisms in the orexin system (focusing on a polymorphism associated with nicotine dependence). (2017)
  • Author(s): Nishizawa D, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Association of Proopioimeranocortin gene polymorphism with vulnerability to alcohol dependence in Japanese. (2017)
  • Author(s): Kasai S, Nishizawa D, Higuchi S, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Genome-wide association study identifies candidate loci associated with intraoperative remifentanil infusion rate in patients undergoing laparoscopic-assisted colectomy. (2017)
  • Author(s): Nishizawa D, Mieda T, Tsujita M, Yamaguchi S, Kasai S, Hasegawa J, Fukuda K, Kitamura A, Hayashida M, Ikeda K
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] The relationship between stress and alcohol consumption in female mice. (2017)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Uhl GR, Ikeda K, Sora I
  • Organizer: 5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017)
  • Int'l Joint Research
• [Presentation] Distinct roles of opioid and dopamine systems in lateral hypothalamic intracranial self-stimulation. (2016)
  • Author(s): Ikeda K, Ide S, Takahashi T, Takamatsu Y, Uhl GR, Niki H, Sora I
  • Organizer: The 55th Annual Meeting of the American College of Neuropsychopharmacology (ACNP 55th Annual Meeting)
  • Place of Presentation: Hollywood, USA
  • Year and Date: 2016-12-05
  • Int'l Joint Research
• [Presentation] 本邦の病院小児科におけるTSC患者の診療実態調査. (2016)
  • Author(s): 佐藤敦志, 池田和隆, 水口雅
  • Organizer: 第4回日本結節性硬化症学会学術総会
  • Place of Presentation: 大阪大学銀杏会館（大阪府吹田市）
  • Year and Date: 2016-11-12
• [Presentation] ドーパミン欠乏マウスにおける異常性行動の脳内メカニズム. (2016)
  • Author(s): 藤田雅代, Takeda TC, 萩野洋子, 笠井慎也, 橋本款, 小林和人, 池田和隆
  • Organizer: 第51回日本アルコール・アディクション医学会学術総会
  • Place of Presentation: タワーホール船堀（東京都江戸川区）
  • Year and Date: 2016-10-07
• [Presentation] 脳内自己刺激法を用いた薬物依存性解析および報酬系神経回路の解析. (2016)
  • Author(s): 井手聡一郎, 池田和隆
  • Organizer: 第51回日本アルコール・アディクション医学会学術総会
  • Place of Presentation: タワーホール船堀（東京都江戸川区）
  • Year and Date: 2016-10-07
  • Invited
• [Presentation] 注意欠如/多動性障害モデルマウスにおけるメチルフェニデートの報酬効果. (2016)
  • Author(s): 池窪結子, 井手聡一郎, 高松幸雄, Takeda TC, Nagasawa S, Hua J, Uhl GR, 曽良一郎, 池田和隆
  • Organizer: 第51回日本アルコール・アディクション医学会学術総会
  • Place of Presentation: タワーホール船堀（東京都江戸川区）
  • Year and Date: 2016-10-07
• [Presentation] Genetic mechanisms underlying individual differences in sensitivity to pain and opioids. (2016)
  • Author(s): Ikeda K, Nishizawa D, Hayashida M, Fukuda K
  • Organizer: 16th World Congress on Pain
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-09-27
  • Int'l Joint Research / Invited
• [Presentation] Genome-wide association study identifies candidate loci associated with intraoperative remifentanil infusion rate in patients undergoing laparoscopic-assisted colectomy. (2016)
  • Author(s): Nishizawa D, Mieda T, Tsujita M, Yamaguchi S, Kasai S, Hasegawa J, Fukuda K, Kitamura A, Hayashida M, Ikeda K
  • Organizer: 16th World Congress on Pain
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-09-27
  • Int'l Joint Research
• [Presentation] 注意欠如/多動性障害モデルマウスにおけるメチルフェニデートの報酬効果. (2016)
  • Author(s): 池窪結子, 井手聡一郎, 高松幸雄, Takeda TC, Nagasawa S, Hua J, Uhl GR, 曽良一郎, 池田和隆
  • Organizer: 平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
  • Place of Presentation: 蓼科グランドホテル滝の湯（長野県茅野市）
  • Year and Date: 2016-09-16
• [Presentation] 鎮痛薬感受性と関連するオピオイドペプチド遺伝子多型の解析. (2016)
  • Author(s): 笠井慎也, 西澤大輔, 林田眞和, 長島誠, 加藤良二, 池田和隆
  • Organizer: 第3回包括的緩和医療科学学術研究会・第4回Tokyo疼痛緩和次世代研究会 合同研究会
  • Place of Presentation: TKPガーデンシティ永田町（東京都千代田区）
  • Year and Date: 2016-08-28
• [Presentation] Cav2.3(R型)電位依存性Ca2+チャネル遺伝子多型と鎮痛薬感受性との関連. (2016)
  • Author(s): 井手聡一郎, 西澤大輔, 福田謙一, 笠井慎也, 長谷川準子, 林田眞和, 池田和隆
  • Organizer: 第36回鎮痛薬・オピオイドペプチドシンポジウム
  • Place of Presentation: 北海道大学薬学部（北海道札幌市）
  • Year and Date: 2016-08-20
• [Presentation] タバコ・ニコチン依存に影響を及ぼすオピオイド受容体関連遺伝子. (2016)
  • Author(s): 笠井慎也, 西澤大輔, 佐藤直美, 谷岡書彦, 椙村春彦, 池田和隆
  • Organizer: 第36回鎮痛薬・オピオイドペプチドシンポジウム
  • Place of Presentation: 北海道大学薬学部（北海道札幌市）
  • Year and Date: 2016-08-20
• [Presentation] 遺伝子多型と術後オピオイド. (2016)
  • Author(s): 池田和隆
  • Organizer: 第6回術後疼痛懇話会
  • Place of Presentation: 青蓮会館（京都府京都市）
  • Year and Date: 2016-07-29
  • Invited
• [Presentation] NMDA receptor channel GluN2D subunit as a target molecule for medicines for mental disorders. (2016)
  • Author(s): Ikeda K, Hagino Y, Ide S
  • Organizer: 第39回日本神経科学大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-07-21
  • Invited
• [Presentation] 喫煙関連遺伝子多型の同定とその機能解析. (2016)
  • Author(s): 池田和隆, 西澤大輔, 笠井慎也, 高松幸雄, 萩野洋子, 椙村春彦
  • Organizer: 公益財団法人喫煙科学研究財団 第31回平成27年度助成研究発表会
  • Place of Presentation: 京王プラザ（東京都新宿区）
  • Year and Date: 2016-07-20
• [Presentation] Prediction formulas for individual opioid analgesic requirements based on genetic polymorphism analyses. (2016)
  • Author(s): Nishizawa D, Yoshida K, Ichinomiya T, Ichinohe T, Hayashida M, Fukuda K, Ikeda K
  • Organizer: The International Narcotics Research Conference 2016
  • Place of Presentation: Bath, UK
  • Year and Date: 2016-07-14
  • Int'l Joint Research
• [Presentation] Increased number of glial and neuronal cells in the periaqueductal gray matter (PAG) of mu-opioid receptor knockout mice. (2016)
  • Author(s): Sasaki K, Sora I, Kasahara Y, Ikeda K, Hall FS, Uhl GR, Kawashima R
  • Organizer: The International Narcotics Research Conference 2016
  • Place of Presentation: Bath, UK
  • Year and Date: 2016-07-11
  • Int'l Joint Research
• [Presentation] Sex differences in voluntary drinking by mu-opioid receptor knockout mice following early stress. (2016)
  • Author(s): Moriya Y, Kasahara Y, Hall FS, Uhl GR, Ikeda K, Sora I
  • Organizer: The International Narcotics Research Conference 2016
  • Place of Presentation: Bath, UK
  • Year and Date: 2016-07-11
  • Int'l Joint Research
• [Presentation] オピオイド感受性関連遺伝子多型の同定とテーラーメイド疼痛治療の開始. (2016)
  • Author(s): 池田和隆, 西澤大輔, 福田謙一, 林田眞和
  • Organizer: 日本ペインクリニック学会第50回大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-07-08
  • Invited
• [Presentation] The abolished rewarding effect of methylphenidate in dopamine transporter knockout mice, a model for attention deficit/hyperactivity disorder. (2016)
  • Author(s): Ide S, Takamatsu Y, Ikekubo Y, Takeda TC, Nagasawa S, Hua J, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Transcriptome analysis in Tsc2 heterozygous knockout mice. (2016)
  • Author(s): Kasai S, Sato A, Kashii H, Kobayashi T, Hino O, Mizuguchi M, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Genome-wide association study identifies candidate loci associated with postoperative fentanyl requirements after laparoscopic-assisted colectomy. (2016)
  • Author(s): Nishizawa D, Mieda T, Nakagawa H, Tsujita M, Imanishi H, Terao K, Yoshikawa H, Itoh K, Amano K, Tashiro J, Ishii T, Ariyama J, Yamaguchi S, Kasai S, Hasegawa J, Ikeda K, Kitamura A, Hayashida M
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] c-Fos immunoreactivity in hypoactive and hyperactive Dopamine-deficient mice. (2016)
  • Author(s): Takeda TC, Fujita M, Hagino Y, Mizuguchi M, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Opposite associations between the rs3845446 single-nucleotide polymorphism of the CACNA1E gene and postoperative pain-related phenotypes in gastrointestinal surgery versus previously reported orthognathic surgery. (2016)
  • Author(s): Amano K, Nishizawa D, Mieda T, Tsujita M, Kitamura A, Hasegawa J, Inada E, Hayashida M, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Association between the rs7583431single-nucleotide polymorphism close to the activating transcription factor 2 (ATF2) gene and the analgesic effect of fentanyl in the preoperative cold pressor-induced pain test. (2016)
  • Author(s): Aoki Y, Nishizawa D, Yoshida K, Hasegawa J, Kasai S, Takahashi K, Koukita Y, Ichinohe T, Hayashida M, Fukuda K, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Therapeutic effects of cholinergic drug on mechanical allodynia in the mouse partial sciatic nerve ligation model. (2016)
  • Author(s): Yamanishi Y, Takamatsu Y, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] Effects of chronic tryptophan depletion on autism spectrum disorder like behaviors in serotonin transporter knockout and heterozygous mice. (2016)
  • Author(s): Tanaka M, Sato A, Hagino Y, Sora I, Murphy D, Ikeda K
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-04
  • Int'l Joint Research
• [Presentation] Methamphetamine induced changes of monoamine neurotransmission in 5-HT1B KO mice. (2016)
  • Author(s): Moriya Y, Kasahara Y, Hagino Y, Hall FC, Hen R, Ikeda K, Uhl GR, Sora I
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-04
  • Int'l Joint Research
• [Presentation] Genetic polymorphisms commonly associated with sensitivity to addictive substances. (2016)
  • Author(s): Ikeda K, Nishizawa D, Fukuda K, Hayashida M, Higuchi S, Sugimura H, Sora I
  • Organizer: 30th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-04
  • Int'l Joint Research / Invited
• [Presentation] レミフェンタニル・プロポフォール全静脈麻酔中にフェンタニルの追加投与を必要とした症例の遺伝子多型. (2016)
  • Author(s): 髙橋香央里, 福田謙一, 西澤大輔, 笠井慎也, 須野学, 髙北義彦, 一戸達也, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] SCN9A遺伝子の一塩基多型rs6746030のマイナーアレル保有者に対する術後鎮痛法の、相関研究および電気生理学的研究に基づく検討. (2016)
  • Author(s): 天野功二郎, 堀下貴文, 西澤大輔, 三枝勉, 辻田美紀, 長島誠, 加藤良二, 長谷川準子, 北村晶, 川崎貴士, 林田眞和, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] Activating transcription factor 2(ATF2)遺伝子近傍の遺伝子多型rs7583431と冷水誘発疼痛試験におけるフェンタニルの鎮痛効果との関連. (2016)
  • Author(s): 青木謙典, 西澤大輔, 吉田香織, 長谷川準子, 笠井慎也, 髙橋香央里, 髙北義彦, 一戸達也, 林田眞和, 福田謙一, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] マウスでの坐骨神経部分結紮後のアロディニアに対するコリン系薬物の治療効果. (2016)
  • Author(s): 山西嘉晴, 高松幸雄, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] 注意欠如/多動性障害モデルマウスにおけるメチルフェニデートの報酬効果の変化. (2016)
  • Author(s): 井手聡一郎, 高松幸雄, 池窪結子, 武田大志クラーク, 長澤セーラ, Hua J, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] 低活動と多動時のドーパミン欠乏マウスのc-Fos免疫反応性. (2016)
  • Author(s): Takeda TC, 藤田雅代, 萩野洋子, 水口雅, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] セロトニントランスポーターノックアウトおよびヘテロ欠損マウスにおける自閉症様行動とトリプトファン欠乏食による改善効果. (2016)
  • Author(s): 田中美歩, 佐藤敦志, 萩野洋子, 曽良一郎, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
• [Presentation] 神経精神薬理学の動向：国際連携と学術会議の視点から. (2016)
  • Author(s): 池田和隆, 山脇成人
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-03
  • Invited
• [Presentation] ゲノムワイド関連解析（GWAS）による腹腔鏡補助下大腸切除術後フェンタニル必要量に影響する遺伝子多型の同定. (2016)
  • Author(s): 西澤大輔, 三枝勉, 中川秀之, 辻田美紀, 今西宏和, 寺尾和久, 吉川博昭, 伊藤一志, 天野功二郎, 田代浄, 石井利昌, 有山淳, 山口茂樹, 笠井慎也, 長谷川準子, 中山京子, 江畑裕子, 池田和隆, 北村晶, 林田眞和
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
• [Presentation] 日本人におけるAUTS2遺伝子多型rs6943555と人格特性との関連研究. (2016)
  • Author(s): 成田心, 岩橋和彦, 吉原英児, 西澤大輔, 石郷岡純, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
• [Presentation] 健常者におけるストレス反応の性差：トランスローケーター蛋白質（TSPO）、コルチゾール、状態・特性不安検査（STAI）による検討. (2016)
  • Author(s): 中本百合江, 中村和彦, 池田和隆, 吉井光信
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
• [Presentation] オピオイド投与中の神経因性疼痛患者へのＥＣＴによる鎮痛効果. (2016)
  • Author(s): 岩田健, 小林雪乃, 米良仁志, 土井永史, 諏訪浩, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
• [Presentation] インターロイキン17Aが発達障害、精神疾患等に及ぼす影響について. (2016)
  • Author(s): 大岡静衣, 池田和隆
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
• [Presentation] 知的障害と妊娠期における物質曝露. (2016)
  • Author(s): 古田島(村上)浩子, 池田和隆, 内野茂夫
  • Organizer: 第46回日本神経精神薬理学会年会(JSNP)
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-07-02
  • Invited
• [Presentation] オピオイド不適切使用の評価と中止法において遺伝子検査が貢献する可能性. (2016)
  • Author(s): 池田和隆, 西澤大輔, 林田眞和, 福田謙一
  • Organizer: 第21回日本緩和医療学会学術大会
  • Place of Presentation: 国立京都国際会館（京都府京都市）
  • Year and Date: 2016-06-18
  • Invited
• [Presentation] 緩和医療領域における遺伝子診断とテーラーメード医療の現状と将来展望. (2016)
  • Author(s): 池田和隆
  • Organizer: 第10回日本緩和医療薬学会年会
  • Place of Presentation: アクトシティ浜松コングレスセンター（静岡県浜松市）
  • Year and Date: 2016-06-05
  • Invited
• [Presentation] 統合失調症と依存性薬物. (2016)
  • Author(s): 池田和隆
  • Organizer: 第41回新潟精神医学懇話会
  • Place of Presentation: ホテル日航新潟（新潟県新潟市）
  • Year and Date: 2016-05-31
  • Invited
• [Presentation] Association between UGT2B7 gene polymorphisms and fentanyl sensitivity in patients undergoing orthognathic surgery. (2016)
  • Author(s): Muraoka W, Saisu H, Sato H, Usuda S, Inoue M, Ochiai S, Nishizawa D, Hasegawa J, Kasai S, Nakagawa T, Wajima K, Fukuda K, Ikeda K
  • Organizer: American Academy of Orofacial Pain
  • Place of Presentation: Lake Buena Vista, USA
  • Year and Date: 2016-04-15
  • Int'l Joint Research
• [Book] Addiction Medicine (Second Edition)【分担執筆】 (2016)
  • Author(s): Nishizawa D, Ikeda K
  • Total Pages: 672
  • Publisher: OXFORD UNIVERSITY PRESS
• [Book] The Neuropathology of Drug Addictions and Substance Misuse. Volume 1(VR Preedy, Ed) (2016)
  • Author(s): Nishizawa D, Ikeda K
  • Total Pages: 1132
  • Publisher: Academic Press
• [Book] The Neuropathology of Drug Addictions and Substance Misuse. Volume 2 (VR Preedy, Ed) (2016)
  • Author(s): Yamamoto H, Sawada W, Kamegaya E, Hagino Y, Ikeda K, Sora I, Mishina M, Yamamoto T
  • Total Pages: 1143
  • Publisher: Academic Press
• [Remarks] 公益財団法人東京都医学総合研究所ホームページ
  • URL: http://www.igakuken.or.jp/
• [Remarks] 依存性薬物プロジェクトホームページ
  • URL: http://www.igakuken.or.jp/abuse/