| Project/Area Number |
16K15702
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
高倉 正博 金沢大学, 附属病院, 准教授 (20313661)
大黒 多希子 金沢大学, 学際科学実験センター, 教授 (30767249)
服部 明 京都大学, 薬学研究科, 准教授 (50300893)
河崎 洋志 金沢大学, 脳・肝インターフェースメディシン研究センター, 教授 (50303904)
荒木 慶彦 順天堂大学, 医学(系)研究科(研究院), 先任准教授 (70250933)
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| Project Period (FY) |
2016-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | laeverin / 臍帯血 / 初期絨毛 / hTERT / Oct4 / テロメラーゼ活性 / 胎児循環幹細胞 / ヒト絨毛 |
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| Outline of Final Research Achievements |
By this project, laeverin-positive cells were successfully isolated from umbilical cord blood and chorionic villous tissues. Consequently, we have become able to analyze their gene and protein expression profiles. This study also demonstrated the precise localization of laeverin-positive cells in the hunan chorionic villous tissues in the early pregnancy. We hope that these findings will contribute to analyzing cell differentiation mechanisms in the field of regenerative or reproductive medicine.
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