| Project/Area Number |
16K15722
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
Ikegami Taro 琉球大学, 医学(系)研究科(研究院), 助教 (00754409)
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| Co-Investigator(Kenkyū-buntansha) |
平川 仁 琉球大学, 医学部附属病院, 講師 (50437993)
又吉 宣 琉球大学, 医学研究科, 助教 (60448587)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 術中イメージング / プロテオグリーン / ガンマーグルタミルトランスフェラーゼ1 / GGT1 / イメージング / 頭頸部癌 / 可視化 / 微小癌 / イメージング質量分析 |
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| Outline of Final Research Achievements |
This study aims to validate whether the head and neck microcancer can be visualized using novel fluorochrome probe, Proteogreen to completely eliminate head and neck cancer in the operation in the future. We succeeded in visualization with some head and neck cancers. However, normal glandular tissue, fibrous connective tissue, cartilage and lymphocytes were also visualized in almost tumors. The further study will be required for establishment of intraoperative imaging with this probe.
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