| Project/Area Number |
16K15760
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Emergency medicine
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| Research Institution | Kyoto University |
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Principal Investigator |
Koike Kaoru 京都大学, 医学研究科, 教授 (10267164)
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| Co-Investigator(Kenkyū-buntansha) |
平川 慶子 日本医科大学, 医学部, 助教 (30165162)
金涌 佳雅 日本医科大学, 医学部, 講師 (80465343)
佐藤 格夫 京都大学, 医学研究科, 准教授 (30409205)
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| Project Period (FY) |
2016-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 近赤外スペクトル / 臓器障害 / リアルタイム / モニタリング / 小腸 / 虚血 / 再灌流 / 近赤外分光法 / 腸管 / 組織障害 |
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| Outline of Final Research Achievements |
Near infrared (NIR) spectroscopy is a noninvasive, contactless and real-time analytical technology that may yield a variety of promising bedside monitoring systems in the field of emergency and critical care medicine. After intestinal ischemia (3h) or intestinal ischemia/reperfusion (3h/1h) was conducted in rats by superior mesenteric artery occlusion, NIR spectra of the intestine were obtained in vivo using ultra-compact NIR spectrometer. When the full range of NIR spectra observed were analyzed by chemometric technique, the temporal change of intestinal tissue injury was clearly estimated.
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