Development of care program analyzing autonomic nervous function in cancer patients.
| Project/Area Number |
16K15903
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical nursing
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Yamanaka Ryuya 京都府立医科大学, 医学部, 教授 (20323991)
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| Co-Investigator(Kenkyū-buntansha) |
早野 あづさ 京都府立医科大学, 医学(系)研究科(研究院), 研究員 (10379018)
川口 淳 佐賀大学, 医学部, 教授 (60389319)
吉岡 さおり 京都府立医科大学, 医学部, 准教授 (60454881)
岩脇 陽子 京都府立医科大学, 医学部, 教授 (80259431)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | がん患者 / 自律神経機能 / ケアプログラム / 心理学的変化 / 看護ケア / 臨床 / 癌 / 脳神経 / 生理学 |
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| Outline of Final Research Achievements |
The objective of this study was to assess, using physiological and psychological indices, the effects of mechanical bathing care for patients in the terminal stage of cancer. The heart rate variability analysis method was used to measure autonomic nervous system function. The patients' state of anxiety was assessed using the State-Trait Anxiety Inventory (STAI), a psychological index, and patients' verbal responses were also collected after mechanical bathing.Twenty-four patients were enrolled in this study. Their sympathetic and parasympathetic nervous activity did not differ before and after bathing. A significant difference was found between pre- and post-bathing anxiety, as evaluated by STAI (P < 0.0001). Patients were more relaxed after mechanical bathing according to STAI evaluation and their verbal responses.The findings suggest that the method of bathing used in this study is safe and pain-relieving for terminal stage cancer patients.
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Report
(3 results)
Research Products
(37 results)
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[Journal Article] Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma.2018
Author(s)
Takashima Y, Sasaki Y, Hayano A, Homma J, Fukai J, Iwadate Y, Kajiwara K, Ishizawa S, Hondoh H, Tokino T, Yamanaka R.
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Journal Title
Oncotarget
Volume: in press
Related Report
Peer Reviewed / Open Access
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[Journal Article] Late relapse of primary central nervous system lymphoma.2017
Author(s)
Yamanaka R, Morii K, Shinbo Y, Sano M, Homma J, Tsuchiya N, Yajima N, Tsukamoto Y, Ogura R,Natsumeda M, Aoki H, Akiyama K, Saitoh T, Tamura T, Hondoh H, Kawaguchi A, Takahashi H, and Fujii Y.
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Journal Title
Leukemia Lymphoma
Volume: 58
Pages: 475-477
Related Report
Peer Reviewed
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[Journal Article] Long-term survivors of primary central nervous system lymphoma.2017
Author(s)
Yamanaka R, Morii K, Sano M, Homma J, Yajima N, Tsukamoto Y, Ogura R, Natsumeda M, Aoki H, Akiyama K, Saitoh T, Hondoh H, Kawaguchi A, Takahashi H, Fujii Y.
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Journal Title
Jpn J Clin Oncol
Volume: 47
Issue: 2
Pages: 101-107
DOI
Related Report
Peer Reviewed
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[Journal Article] Stat3 inhibitor abrogates the expression of PD-1 ligands on lymphoma cell lines2017
Author(s)
Ma C, Horlad H, Pan C, Yano H, Ohnishi K, Fujiwara Y, Matsuoka M, Lee A, Niidome T, Yamanaka R, Takeya M, Komohara Y
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Journal Title
Journal of Clinical and Experimental Hematopathology
Volume: 57
Issue: 1
Pages: 21-25
DOI
NAID
ISSN
1346-4280, 1880-9952
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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