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Constructing nonlinear dynamical analysis method for action potential shape

Research Project

Project/Area Number 16K16138
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Kansei informatics
Research InstitutionThe University of Tokyo (2018)
Tokyo University of Science (2016-2017)

Principal Investigator

Fujiwara Kantaro  東京大学, ニューロインテリジェンス国際研究機構, 特任准教授 (00557704)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords非定常確率過程 / 統計量 / 数理工学 / 神経科学 / 生物物理 / 生物・生体工学 / 統計数学
Outline of Final Research Achievements

I have proposed and investigated several statistical analysis methods for neuronal spike trains. As a result, our new analysis method seems to be effective for the time series with long time correlation or stationary data, which is often difficult to be applied for other conventional analysis methods. Moreover, I evaluated the complexity of spike trains and investigated the relationship between time series and neuron models.

Academic Significance and Societal Importance of the Research Achievements

本研究成果により、神経活動からこれまでとは異なる新たな情報を抽出することが可能となった。これは、脳神経活動からいかに情報を抽出できるかという脳神経科学における根源的な問いに対する一つの答えとして、意義があるといえる。
また現状の機械学習的なAIとは異なる脳に倣った情報処理システムを構築するには、脳神経細胞の情報表現様式を理解することが必要不可欠である。その点で、本研究成果のような神経活動を数理的に抽出する試みは、その情報表現様式を理解する上で一定の意義があるといえる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (51 results)

All 2019 2018 2017 2016

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (46 results) (of which Int'l Joint Research: 13 results,  Invited: 1 results)

  • [Journal Article] Threshold-varying integrate-and-fire model reproduces distributions of spontaneous blink intervals2018

    • Author(s)
      Ryota Nomura,Ying-Zong Liang,Kenji Morita,Kantaro Fujiwara and Tohru Ikeguchi
    • Journal Title

      PLoS ONE

      Volume: 13 Issue: 10 Pages: 0306258-0306258

    • DOI

      10.1371/journal.pone.0206528

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Izhikevichニューロンモデルにおけるカオス応答とカオス同期2017

    • Author(s)
      内木楓,島田裕,藤原寛太郎,池口徹
    • Journal Title

      電子情報通信学会論文誌A

      Volume: J100-A Pages: 195-204

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reproducing Infra-Slow Oscillations with Dopaminergic Modulation2017

    • Author(s)
      Toshihiro Kobayashi,Yutaka Shimada,Kantaro Fujiwara and Tohru Ikeguchi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 2411-2411

    • DOI

      10.1038/s41598-017-02366-z

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chaotic Neurodynamical search with small number of neurons for solving QAP2017

    • Author(s)
      Hikaru Ohnishi,Yutaka Shimada,Kantaro Fujiwara and Tohru Ikeguchi
    • Journal Title

      Nonlinear Theory and Its Applications, IEICE

      Volume: 8 Issue: 3 Pages: 255-265

    • DOI

      10.1587/nolta.8.255

    • NAID

      130006903507

    • ISSN
      2185-4106
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Numerical analysis of bursting activity in an isolated pancreatic <I>&beta;</I>-cell model2016

    • Author(s)
      H. Ando, K. Fujiwara
    • Journal Title

      Nonlinear Theory and Its Applications, IEICE

      Volume: 7 Issue: 2 Pages: 217-225

    • DOI

      10.1587/nolta.7.217

    • NAID

      130005142580

    • ISSN
      2185-4106
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 興奮性/抑制性ニューロン比率が発火率と学習に与える効果2019

    • Author(s)
      宮南風,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会 2019年総合大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] TRPM2 チャネルがインスリン分泌に与える影響の調査2019

    • Author(s)
      笠原宏太朗,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会 2019年総合大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Synaptic Dynamics in ISO by Dopaminergic Modulation and Inhibitory Synaptic Learnings2018

    • Author(s)
      Tohru Ikeguchi, Yutaka Shimada, Kantaro Fujiwara, Sakura Rai, and Toshihiro Kobayashi
    • Organizer
      2018 International Symposium on Nonlinear Theory and its Applications
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Modeling Ubiquitous Chaotic Activity in Neural Systems2018

    • Author(s)
      Kantaro Fujiwara
    • Organizer
      The 3rd Neuromorphic Research Retreat in AIST
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Investigation of ISO Generated by Dopaminergic Modulation and Inhibitory Synaptic Learning2018

    • Author(s)
      Sakura Rai, Mayu Aoki, Yutaka Shimada, Kantaro Fujiwara, and Tohru Ikeguchi
    • Organizer
      International Conference on Mathematical NeuroScience
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] k番目の最短経路を使用したグラフ的シュタイナー木構築法2018

    • Author(s)
      藤田実沙,木村貴幸,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 重み付き有向ネットワークの指標を用いた多言語間の比較2018

    • Author(s)
      多々良真弓美,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] メトロノーム同期実験において出現するカオス応答の解析2018

    • Author(s)
      中川祐季,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 整数ロジスティック写像の応答より生成した乱数列の統計的解析2018

    • Author(s)
      金丸志生,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 数理モデルによる膵β細胞のTRPM2チャネル活性の再現2018

    • Author(s)
      笠原宏太朗,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 高速株式取引データに対する非線形解析2018

    • Author(s)
      山本紘平,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] サロゲートデータ法を用いたカオスMIMOシステムの性能解析2018

    • Author(s)
      山崎凌,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Analysis of Information Diffusion Using a Mathematical Model2017

    • Author(s)
      石黒 譲,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-03-22
    • Related Report
      2016 Research-status Report
  • [Presentation] Differences between Japanese and English Languages from the Viewpoint of Network Motifs2017

    • Author(s)
      多々良 真弓美,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-03-22
    • Related Report
      2016 Research-status Report
  • [Presentation] Chaotic Synchronization Observed in Gap-Junctionally Coupled Neuron Model2017

    • Author(s)
      内木 楓,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-03-22
    • Related Report
      2016 Research-status Report
  • [Presentation] 数理モデルを用いた神経雪崩現象の解析2017

    • Author(s)
      青木 舞優,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-03-22
    • Related Report
      2016 Research-status Report
  • [Presentation] 環境変動を考慮した資源収支モデルによる一斉開花・隔年結実現象2017

    • Author(s)
      栗田 いずみ,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会総合大会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2017-03-22
    • Related Report
      2016 Research-status Report
  • [Presentation] キーパス近傍に基づいたカオスニューラルネットワークによるグラフ的シュタイナー木問題の解法2017

    • Author(s)
      藤田実沙,木村貴幸,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] TRPM2チャネルの膜電位特性の数理モデル解析2017

    • Author(s)
      藤原寛太郎,安東弘泰,池口徹,吉田昌史,加計正文
    • Organizer
      日本糖尿病学会年次学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] 頂点に基づく局所探索法を用いたカオスニューラルネットワークによるグラフ的シュタイナー木問題の解法2017

    • Author(s)
      藤田実沙,木村貴幸,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] スケールフリー性とクラスタ性が共存するネットワーク上での情報拡散の解析2017

    • Author(s)
      石黒譲,島田裕,藤原寛太郎,池口徹,
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 数値計算による4台のメトロノームの同期領域の調査2017

    • Author(s)
      塩見優介,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 複雑ネットワーク解析による異言語間の比較調査2017

    • Author(s)
      多々良真弓美,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Izhikevichニューロンモデルにおけるノイズ電流印加による信頼性の上昇2017

    • Author(s)
      内木楓,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] メトロノームにおける有色ノイズによる共通ノイズ同期現象2017

    • Author(s)
      船木怜大成,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会ソサイエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Evaluation of the performance of the chaotic neural network for solving the Steiner tree problem in graphs with incidence costs2017

    • Author(s)
      Misa Fujita, Takayuki Kimura, and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and its Applications (NOLTA2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effect of connectivity weights of inhibitory neurons in neuronal avalanches2017

    • Author(s)
      Mayu Aoki, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and its Applications (NOLTA2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Mathematical Model of TRPM2 Activation in Pancreatic β-cells2017

    • Author(s)
      Kantaro Fujiwara, Hiroyasu Ando, Tohru Ikeguchi, Masashi Yoshida and Masafumi Kakei
    • Organizer
      International Symposium on Nonlinear Theory and its Applications (NOLTA2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] メトロノーム数が同期に与える影響2017

    • Author(s)
      塩見優介,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会非線形問題研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] 神経活動リズムと神経雪崩現象の関係2017

    • Author(s)
      青木舞優,加藤秀行,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会非線形問題研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] ドーパミンの作用と抑制性シナプスの学習による低周波リズムの生成2017

    • Author(s)
      頼さくら,島田裕,藤原寛太郎,池口徹
    • Organizer
      電子情報通信学会非線形問題研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] Computation of Visual Neurons in LGN-V1 Transmission2016

    • Author(s)
      Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Analysis of Synaptic Dynamics during Infra-Slow Oscillation2016

    • Author(s)
      Toshihiro Kobayashi, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Which vertices affect the spread of disease in temporal networks?2016

    • Author(s)
      Koshi Abe, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] A Chaotic Search with the Effect of Wide Range Search for Solving QAP2016

    • Author(s)
      Hikaru Ohnishi, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Numerical Analysis on Synchronization of Four Metronomes2016

    • Author(s)
      Yusuke Shiomi, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Analysis on Differences of Japanese and English languages by the Complex Network Theory2016

    • Author(s)
      Mayumi Tatara, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Synchronization in a Coupled Izhikevich Neuron Model2016

    • Author(s)
      Kaede Naiki, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Irregularity of Inter-Event Interval of Diastrophism2016

    • Author(s)
      Keisuke Miyata, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      International Symposium on Nonlinear Theory and Its Applications
    • Place of Presentation
      静岡県熱海市
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] How contact timings affect spread of disease in human interaction networks2016

    • Author(s)
      Koshi Abe, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] Synaptic Dynamics during Infra-Slow Oscillation2016

    • Author(s)
      Toshihiro Kobayashi, Yutaka Shimada, Kantaro Fujiwara, Tohru Ikeguchi
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] A Chaotic Search with Small Number of Neurons for Solving Quadratic Assignment Problem2016

    • Author(s)
      Hikaru Ohnishi, Yutaka Shimada, Kantaro Fujiwara and Tohru Ikeguchi
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] メトロノーム同期におけるトランジェントカオスについて2016

    • Author(s)
      塩見 優介,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] 頂点間の最短距離と局所的なクラスタ係数の分布について2016

    • Author(s)
      多々良 真弓美,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] Gap junction結合Izhikevichニューロンモデルにおけるカオス2016

    • Author(s)
      内木 楓,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report
  • [Presentation] 大規模地震の地殻変動発生間隔の不規則性2016

    • Author(s)
      宮田 佳祐,島田 裕,藤原 寛太郎,池口 徹
    • Organizer
      電子情報通信学会NOLTAソサイエティ大会
    • Place of Presentation
      東京都葛飾区
    • Year and Date
      2016-06-12
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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