Comprehensive search for vegetable oils that improve the absorption rate of fat-soluble component and the effects of cooking
| Project/Area Number |
16K16269
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
Sakamoto Yuka 神戸学院大学, 栄養学部, 実験助手 (20368484)
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| Project Period (FY) |
2016-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 植物油 / 脂溶性成分 / 膜透過性 / PAMPA / Caco-2細胞 / PAMPA法 / ケルセチン / 吸収 / 調理科学 |
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| Outline of Final Research Achievements |
Fat-soluble component such as vitamins and flavonoids are known to improve their absorption rate by cooking with lipids, and the absorption rate is also improved by a small amount of coexisting phospholipids. In this study, We aimed to objectively quantify the compatibility of fat-soluble ingredients and vegetable oil by an artificial membrane permeability test using the PAMPA method. Furthermore, the effect of cooking on fat-soluble components was also verified. Among commonly sold vegetable oils, the membrane permeability was verified by using corn oil as a vegetable oil with a high phospholipid content and using quercetin as a fat-soluble component. The membrane permeability of fat-soluble components increased in the presence of vegetable oil. Therefore, it was suggested that the fatty acid composition of the phospholipid (PC)-added corn oil may have an effect.
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| Academic Significance and Societal Importance of the Research Achievements |
人工膜透過試験（PAMPA法）により食品と植物油の相性を数値化することで、脂溶性成分の吸収率が向上する植物油が客観的に判断できる。簡単明瞭で消費者に受け入れられやすく、学童の食育教育にも寄与する。また脂質をうまく利用し過剰摂取を減らせば、肥満・メタボリックシンドローム・冠動脈疾患などを減らし、将来的には生活習慣病などの予防・改善等に役立つものと考えられる。
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Report
(8 results)
Research Products
(2 results)
