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Comprehensive search for vegetable oils that improve the absorption rate of fat-soluble component and the effects of cooking

Research Project

Project/Area Number 16K16269
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits
Research InstitutionKobe Gakuin University

Principal Investigator

Sakamoto Yuka  神戸学院大学, 栄養学部, 実験助手 (20368484)

Project Period (FY) 2016-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords植物油 / 脂溶性成分 / 膜透過性 / PAMPA / Caco-2細胞 / PAMPA法 / ケルセチン / 吸収 / 調理科学
Outline of Final Research Achievements

Fat-soluble component such as vitamins and flavonoids are known to improve their absorption rate by cooking with lipids, and the absorption rate is also improved by a small amount of coexisting phospholipids. In this study, We aimed to objectively quantify the compatibility of fat-soluble ingredients and vegetable oil by an artificial membrane permeability test using the PAMPA method. Furthermore, the effect of cooking on fat-soluble components was also verified. Among commonly sold vegetable oils, the membrane permeability was verified by using corn oil as a vegetable oil with a high phospholipid content and using quercetin as a fat-soluble component. The membrane permeability of fat-soluble components increased in the presence of vegetable oil. Therefore, it was suggested that the fatty acid composition of the phospholipid (PC)-added corn oil may have an effect.

Academic Significance and Societal Importance of the Research Achievements

人工膜透過試験(PAMPA法)により食品と植物油の相性を数値化することで、脂溶性成分の吸収率が向上する植物油が客観的に判断できる。簡単明瞭で消費者に受け入れられやすく、学童の食育教育にも寄与する。また脂質をうまく利用し過剰摂取を減らせば、肥満・メタボリックシンドローム・冠動脈疾患などを減らし、将来的には生活習慣病などの予防・改善等に役立つものと考えられる。

Report

(8 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (2 results)

All 2018 2017

All Presentation (2 results)

  • [Presentation] 脂溶性成分の人工膜透過性試験(PAMPA)における植物油中のリン脂質含有量の影響2018

    • Author(s)
      坂本裕香、石井剛志
    • Organizer
      第20回静岡ライフサイエンスシンポジウム
    • Related Report
      2018 Research-status Report
  • [Presentation] フラボノイドの分子会合に寄与する構造特性2017

    • Author(s)
      豊島 亮太、辻 愛、坂本 裕香、川畑 球一、石井 剛志
    • Organizer
      農芸化学会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2017-03-21
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2024-01-30  

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