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Study on a bioassay technique based on ventilatory signal predictor of killifish

Research Project

Project/Area Number 16K16368
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Social systems engineering/Safety system
Research InstitutionKure National College of Technology

Principal Investigator

Akira Hirano  呉工業高等専門学校, 電気情報工学分野, 准教授 (60594778)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywordsバイオアッセイ / メダカ / 生体信号 / 生体情報 / 安全工学・安全科学
Outline of Final Research Achievements

Bioassay monitoring is a method for detecting environmental change using animals. It has an advantage over the traditional chemical analysis methods in continuous monitoring of potential toxicity risks on the animals. Therefore, a bioassay method has been proposed using ventilatory signals of killifish; however, the conventional systems were limited to short-term monitoring. In this study, we developed a system that enables long-term measurement of ventilatory signal continuously. The measurement results demonstrated that the ventilator signal patterns frequently change even under the same water qualities. We also proposed a toxicity detection algorithm for water using one class support vector machine and verified that the algorithm could detect artificial administration of toxic substance within a few hours.

Academic Significance and Societal Importance of the Research Achievements

メダカの生体信号を用いて水質変化を検出するためのアルゴリズムを提示している.また,浄水場をはじめとした水質管理現場において,長時間連続的に水質を監視するためのバイオアッセイシステムについて,具体的なハードウェア例を提示している.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (3 results)

All 2018 2017

All Presentation (3 results)

  • [Presentation] メダカの呼吸波を利用した水の毒性検出アルゴリズムの提案2018

    • Author(s)
      城明舜磨, 平野 旭, 曽 智, 吉田将之, 辻 敏夫
    • Organizer
      平成30年 電気学会 電子・情報・システム部門大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Raspberry Piを用いた呼吸波計測システムの改良2017

    • Author(s)
      小笠原 遼一, 平野 旭, 曽 智, 辻 敏夫
    • Organizer
      平成29年度(第68回)電気・情報関連学会中国支部連合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] メダカの呼吸波計測にむけた電極配置の提案2017

    • Author(s)
      城明 舜磨, 平野 旭, 曽 智, 辻 敏夫
    • Organizer
      平成29年度(第68回)電気・情報関連学会中国支部連合大会
    • Related Report
      2017 Research-status Report

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Published: 2016-04-21   Modified: 2020-03-30  

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