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Cardiorespiratory fitness and the risk of lifestyle-related diseases: Importance of maintaining a fit level of cardiorespiratory fitness

Research Project

Project/Area Number 16K16591
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionTohoku University

Principal Investigator

Momma Haruki  東北大学, 医学系研究科, 講師 (90633488)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords全身持久力 / 生活習慣病 / 追跡研究 / パネルデータ / 糖尿病 / 高血圧 / 体力 / 観察研究 / コホート研究 / 健康づくりのための身体活動2013 / 心肺体力 / 疫学 / インスリン抵抗性 / 経時変化 / 健康づくりのための身体活動基準2013 / 脂質異常法
Outline of Final Research Achievements

This study aimed to address the question “Does maintaining high level of cardiorespiratory fitness (CRF) result in a decreased risk of lifestyle-related disease?” b a cohort follow-up study. The participants in this study was approximately 7000 men who underwent submaximal exercise tests using a bicycle ergometer before and at baseline, and was followed up for 23 years. The results of this study was as follows: (1) consistently higher level of CRF over time was associated with lower risk of type 2 diabetes (T2DM), (2) achievement of a fit CRF level established in the Japan physical activity guideline for several years was associated with lower subsequent risk of T2DM, and (3) achieving the fitness level recommended in the Japanese guideline three or more times during a 6-year period were associated with lower risk of hypertension.

Academic Significance and Societal Importance of the Research Achievements

定期的な運動を行うことが生活習慣病予防をはじめ健康の維持増進に対して有効であることは当然のこととされている。定期的な運動を行っていれば体力も高く保たれることから、高い体力レベルを保つことは健康の維持増進につながると一般的に考えられている。しかし、体力レベルと生活習慣病の発症リスクを検討した多くの研究は、追跡開始時点の体力のみを検討した研究の結果に基づいており、実際に生活習慣病の発症リスクの低減につながっているかについては直接的な証拠は示されていなかった。本研究はその直接的な証拠を初めて示した研究である。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (16 results)

All 2019 2018 2017 2016

All Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (11 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results)

  • [Journal Article] Frequency of achieving a ‘fit’ cardiorespiratory fitness level and hypertension2019

    • Author(s)
      Momma Haruki、Sawada Susumu S.、Sloan Robert A.、Gando Yuko、Kawakami Ryoko、Miyachi Motohiko、Fukunaka Yasushi、Okamoto Takashi、Tsukamoto Koji、Nagatomi Ryoichi、Blair Steven N.
    • Journal Title

      Journal of Hypertension

      Volume: 37 Issue: 4 Pages: 820-826

    • DOI

      10.1097/hjh.0000000000001935

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study2018

    • Author(s)
      Haruki Momma, Susumu S. Sawada, Robert A. Sloan, Yuko Gando, Ryoko Kawakami, Shin Terada, Motohiko Miyachi, Chihiro Kinugawa, Takashi Okamoto, Koji Tsukamoto, Cong Huang, Ryoichi Nagatomi, Steven N. Blair
    • Journal Title

      Journal of Epidemiology

      Volume: 28 Issue: 5 Pages: 230-236

    • DOI

      10.2188/jea.JE20160199

    • NAID

      130006732083

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2018-05-05
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 集団を対象とする疫学研究とN = 1研究2018

    • Author(s)
      門間陽樹
    • Journal Title

      バイオメカニズム学会誌

      Volume: 印刷中

    • NAID

      130007586519

    • Related Report
      2017 Research-status Report
  • [Journal Article] Consistently high level of cardiorespiratory fitness and incidence of type 2 diabetes2017

    • Author(s)
      Momma H, Sawada SS, Lee IM, Gando Y, Kawakami R, Terada S, Miyachi M, Kinugawa C, Okamoto T, Tsukamoto K, Huang C, Nagatomi R, Blair SN
    • Journal Title

      Medicine & Science in Sports & Exercise

      Volume: 49 Issue: 10 Pages: 2048-2055

    • DOI

      10.1249/mss.0000000000001319

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 「○○は健康にいい」と言うためには?~身近な疑問に答えを出す疫学手法~2017

    • Author(s)
      門間陽樹
    • Journal Title

      東北医学雑誌

      Volume: 129 Pages: 50-50

    • Related Report
      2017 Research-status Report
  • [Presentation] 体力疫学の今とこれから2018

    • Author(s)
      門間陽樹
    • Organizer
      第21回日本運動疫学会学術総会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 体力測定の参加と高血圧発症リスクとの関連:人間ドック受診者を対象とした予備的検討-新潟ウェルネススタディ-2018

    • Author(s)
      門間陽樹、澤田亨、丸藤祐子、川上諒子、宮地元彦、永富良一、田代稔、加藤公則、曽根博仁
    • Organizer
      第21回日本運動疫学会学術総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 研究における統計解析の役割~ 「当たり前」を少しだけ丁寧に深く考えてみる ~2018

    • Author(s)
      門間陽樹
    • Organizer
      日本運動疫学会主催 第4回 運動と健康:分野横断型勉会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 脂質異常症の簡便な予測因子としての体力テストの可能性:コホート研究-Niigata Wellness Study-2018

    • Author(s)
      門間陽樹、澤田亨、丸藤祐子、宮地元彦、永富良一、田代稔、加藤公則、曽根博仁
    • Organizer
      第59回日本人間ドック学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 体力測定・運動負荷試験の評価・活用方法2018

    • Author(s)
      門間陽樹
    • Organizer
      平成29年度運動指導従事者研修会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 長期的な全身持久力の基準値の達成と高血圧発症リスクとの関連:コホート研究2017

    • Author(s)
      門間陽樹、澤田亨、丸藤祐子、宮地元彦、福中康志、岡本隆史、塚本浩二、黄聡、永富良一
    • Organizer
      第27回日本疫学会学術総会
    • Place of Presentation
      山梨県甲府市(ベルクラシック甲府)
    • Year and Date
      2017-01-26
    • Related Report
      2016 Research-status Report
  • [Presentation] Effect of cardiorespiratory fitness on blood glucose trajectory with aging: a cohort study of Japanese men2017

    • Author(s)
      Momma H, Sawada SS, Shimada K, Gando Y, Miyachi M, Kinugawa C, Okamoto T, Tsukamoto K, Huang C, Nagatomi R
    • Organizer
      American College of Sports Medicine 64th Annual Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 全身持久力の基準の維持と高血圧発症リスク:コホート研究2017

    • Author(s)
      門間陽樹, 澤田亨, 丸藤祐子, 宮地元彦, 福中康志, 岡本隆史, 塚本浩二, 黄聡, 永富良一
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 身近な運動疫学研究の実施と注意点2017

    • Author(s)
      門間陽樹
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 長期的な全身持久力の維持と糖尿病発症リスクとの関連:コホート研究 ~全身持久力基準値の妥当性の観点から~2016

    • Author(s)
      門間陽樹、澤田亨、丸藤祐子、川上諒子、宮地元彦、寺田新、絹川千尋、岡本隆史、塚本浩二、黄聡、永富良一
    • Organizer
      第19回日本運動疫学会学術総会
    • Place of Presentation
      東京都西東京市(早稲田大学 東伏見キャンパス)
    • Year and Date
      2016-06-18
    • Related Report
      2016 Research-status Report
  • [Presentation] Higher cardiorespiratory fitness during a given period and lower incidence of type 2 diabetes2016

    • Author(s)
      Haruki Momma, Susumu S. Sawada, I-Min Lee, Yuko Gando, Motohiko Miyachi, Ryoko Kawakami, Chihiro Kinugawa, Takashi Okamoto, Koji Tsukamoto, Cong Huang, Ryoichi Nagatomi, Steven N. Blair FACSM
    • Organizer
      American College of Sports Medicine Annual Meeting 2016
    • Place of Presentation
      Boston, USA (Hynes Convention Center)
    • Year and Date
      2016-05-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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