| Project/Area Number |
16K16594
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | National Agency for the Advancement of Sports and Health (2017)
University of Tsukuba (2016) |
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Principal Investigator |
Akazawa Nobuhiko 独立行政法人日本スポーツ振興センター国立スポーツ科学センター, スポーツ科学部, 契約研究員 (30713250)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 動脈スティフネス / 脳血流 / 認知機能 / 運動トレーニング / 実行機能 / 動脈伸展性 / 有酸素性運動 |
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| Outline of Final Research Achievements |
Age-related decrease in central artery compliance and cerebral blood flow are associated with increase in a risk of dementia. Aerobic exercise has a favorable effect on vascular and cognitive aging. The aim of this study was to investigate that the effect of exercise training on central artery compliance, cerebral blood flow, and cognitive function. A total of 33 middle-aged and older were assigned to the exercise and the control group. Before and after 8 weeks intervention, we measured carotid arterial compliance, oxygenated hemoglobin (oxy-Hb) in prefrontal cortex, and executive function. There are significant ameliorations in carotid arterial compliance, oxy-Hb, and executive function in the exercise group. Exercise training may increase arterial function and cerebral blood flow, and enhances executive function in middle-aged and older adults.
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