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Suppressive effects of aversive stimuli on the relapse of behavior in zebrafish

Research Project

Project/Area Number 16K17366
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionAichi Bunkyo University

Principal Investigator

Kuroda Toshikazu  愛知文教大学, 人文学部, 講師 (80712968)

Research Collaborator Podlesnik Christopher A.  
Cancado Carlos R. X.  
Mizutani Yuto  
Manabe Kazuchika  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsゼブラフィッシュ / 行動の再出現 / 嫌悪刺激 / 弱化 / 強化 / オペラント条件づけ / 再出現 / Relapse / Renewal / Resurgence / 実験系心理学
Outline of Final Research Achievements

This experiment investigated relapse phenomena of previously reinforced and extinguished behavior using zebrafish (Danio rerio), which have been a popular animal model in life science. The relapse phenomena, which have been reported with other species, were replicated with the fish. Next I identified a couple different stimuli that function as an aversive stimulus for zebrafish. Lastly, I examined whether the aversive stimulus would reduce the likelihood of the relapse. The stimulus was presented to a target response during a response-acquisition phase or during an extinction phase. However, the stimulus did not reduce the relapse in either case.

Academic Significance and Societal Importance of the Research Achievements

一度獲得した行動は、それがしばらくの間起こらなくなった後でも、再び出現することがある。これを「行動の再出現」と呼び、犯罪者の刑期後の再犯や、薬物依存といった社会的に望ましくない行動のモデルにもなっている。行動の再出現に対し、抑制効果が期待できるものとして、逮捕など苦い経験がある。しかし、動物を対象とした本研究では、そういった苦い経験に抑制効果はない、あるいは乏しいことを示唆する結果が得られた。これは再犯率の高さにも関係するものと考えられ、別の対策が必要であることを示唆している。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (28 results)

All 2019 2018 2017 2016 Other

All Int'l Joint Research (6 results) Journal Article (9 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 9 results,  Acknowledgement Compliant: 3 results) Presentation (11 results) (of which Int'l Joint Research: 7 results) Funded Workshop (2 results)

  • [Int'l Joint Research] Florida Institute of Technology(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Universidade de Brasilia(ブラジル)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Florida Institute of Technology(米国)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Universidade de Brasília(ブラジル)

    • Related Report
      2017 Research-status Report
  • [Int'l Joint Research] Universidade de Brasilia(ブラジル)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Florida Institute of Technology(米国)

    • Related Report
      2016 Research-status Report
  • [Journal Article] Predator videos and electric shock function as punishers for zebrafish (Danio rerio).2019

    • Author(s)
      KURODA, T., Mizutani, Y., Cancado, C. R. X., & Podlesnik, C. A.
    • Journal Title

      Journal of the Experimental Analysis of Behavior

      Volume: 111 Issue: 1 Pages: 116-129

    • DOI

      10.1002/jeab.494

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A system for the real-time tracking of operant behavior as an application of 3D camera.2018

    • Author(s)
      KURODA, T.
    • Journal Title

      Journal of the Experimental Analysis of Behavior

      Volume: 110 Issue: 3 Pages: 522-544

    • DOI

      10.1002/jeab.471

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Response acquisition by zebrafish (Danio rerio) with delayed reinforcement.2018

    • Author(s)
      KURODA, T., & Mizutani, Y.
    • Journal Title

      Journal of the Experimental Analysis of Behavior.

      Volume: 印刷中 Issue: 3 Pages: 520-532

    • DOI

      10.1002/jeab.324

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reversal learning and resurgence of operant behavior in zebrafish (Danio rerio)2017

    • Author(s)
      KURODA, T., Mizutani, Y., Cançado, C. R. X., & Podlesnik, C. A.
    • Journal Title

      Behavioural Processes

      Volume: 142 Pages: 79-83

    • DOI

      10.1016/j.beproc.2017.06.004

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Operant models of relapse in Zebrafish (Danio rerio): Resurgence, renewal, and reinstatement2017

    • Author(s)
      KURODA, T., Mizutani, Y., Cançado, C. R. X., & Podlesnik, C. A. (2017)
    • Journal Title

      Behavioural Brain Research

      Volume: 335 Pages: 215-222

    • DOI

      10.1016/j.bbr.2017.08.023

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A combination of Raspberry Pi and SoftEther VPN for remotely controlling contingencies2017

    • Author(s)
      KURODA, T.
    • Journal Title

      Journal of the Experimental Analysis of Behavior

      Volume: 108 Issue: 3 Pages: 468-484

    • DOI

      10.1002/jeab.289

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reversal Learning and Resurgence of Operant Behavior in Zebrafish (Danio rerio)2017

    • Author(s)
      Toshikazu Kuroda, Yuto Mizutani, Carlos R. X. Cancado, & Christopher A. Podlesnik
    • Journal Title

      Behavioural Processes

      Volume: -

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A Combination of Raspberry Pi and SoftEther VPN for Controlling Research Devices via the Internet2017

    • Author(s)
      Toshikazu Kuroda
    • Journal Title

      Journal of the Experimental Analysis of Behavior

      Volume: -

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Acquisition of Operant Response by Zebrafish (Danio rerio) with Delayed Reinforcement2017

    • Author(s)
      Toshikazu Kuroda & Yuto Mizutani
    • Journal Title

      Journal of the Experimental Analysis of Behavior

      Volume: -

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] A system for real-time 3D tracking of operant behavior.2018

    • Author(s)
      KURODA, T.
    • Organizer
      Society for Quantitative Analyses of Behavior
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Punishment of zebrafish (Danio rerio) approach behavior with the motion picture of their predator.2018

    • Author(s)
      KURODA, T., Mizutani, Y., Cancado, C. R. X., & Podlesnik, C. A.
    • Organizer
      Association for Behavior Analysis International
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Baseline reinforcement rate increases both resistance to extinction and resurgence of operant behavior in zebrafish.2018

    • Author(s)
      KURODA, T., Mizutani, Y., Cancado, C. R. X., & Podlesnik, C. A.
    • Organizer
      Association for Behavior Analysis International
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Punishment effects of mild electric shock on zebrafish (Danio rerio) behavior.2018

    • Author(s)
      KURODA, T., Mizutani, Y., Cancado, C. R. X., & Podlesnik, C. A.
    • Organizer
      日本行動分析学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Resurgence, renewal, and reinstatement of operant responding in zebrafish (Danio rerio)2017

    • Author(s)
      Toshikazu Kuroda, Yuto Mizutani, Carlos R. X. Cancado, & Christopher A. Podlesnik
    • Organizer
      Association for Behavior Analysis International
    • Place of Presentation
      Denver, Colorado, USA
    • Year and Date
      2017-05-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Raspberry Pi and SoftEther VPN for the Remote Control of Contingencies2017

    • Author(s)
      Toshikazu Kuroda
    • Organizer
      The Society for the Quantitative Analysis of Behavior
    • Place of Presentation
      Denver, Colorado, USA
    • Year and Date
      2017-05-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Raspberry Pi and SoftEther VPN for the remote control of contingencies2017

    • Author(s)
      KURODA, T.
    • Organizer
      Society for Quantitative Analyses of Behavior
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Resurgence, renewal, and reinstatement of operant responding in zebrafish (Danio rerio)2017

    • Author(s)
      KURODA, T., Mizutani, Y., Cançado, C. R. X., & Podlesnik, C. A.
    • Organizer
      Association for Behavior Analysis International
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Punishment with the motion picture of a predator of zebrafish (Danio rerio)2017

    • Author(s)
      KURODA, T., & Mizutani, Y.
    • Organizer
      日本行動分析学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Relations between reinforcement rate and resistance to change in zebrafish (Danio rerio)2017

    • Author(s)
      Mizutani, Y., & KURODA, T.
    • Organizer
      日本行動分析学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 遅延強化によるゼブラフィッシュの反応獲得2016

    • Author(s)
      黒田敏数、水谷優斗
    • Organizer
      日本行動分析学会
    • Place of Presentation
      大阪市立大学
    • Year and Date
      2016-09-09
    • Related Report
      2016 Research-status Report
  • [Funded Workshop] Association for Behavior Analysis International2017

    • Related Report
      2017 Research-status Report
  • [Funded Workshop] Society for Quantitative Analyses of Behavior2017

    • Related Report
      2017 Research-status Report

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Published: 2016-04-21   Modified: 2022-02-21  

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