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Elucidation of lubrication mechanism of biphasic hydrogel and improvement of its lubricating function

Research Project

Project/Area Number 16K18002
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Design engineering/Machine functional elements/Tribology
Research InstitutionTokyo Metropolitan University

Principal Investigator

Yarimitsu Seido  首都大学東京, システムデザイン研究科, 助教 (90723205)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsバイオトライボロジー / 人工軟骨 / ハイドロゲル / 固液二相性潤滑 / 摩擦 / 摩耗 / PVAハイブリッドゲル / 複合化 / PVAハイドロゲル / 予荷重 / 透水性 / 二相性潤滑 / 水和潤滑 / トライボロジー / 生体工学 / 生体材料
Outline of Final Research Achievements

In this study, the influence of pre-loading on tribological behavior of PVA hydrogels and articular cartilage is discussed to elucidating the blubrication mechanism of PVA hydrogels. The increase of pre-loading time at starting frictional motion led to the increase of both friction and wear of PVA-FT gel, PVA-CD gel and articular cartilage. However, PVA-hybrid gel showed low friction with minimum wear regardless of applying pre-load. These results indicated that PVA-hybrid gel has a great potential as an artificial cartilage material.
In addition, we developed the PVA-hybrid gel with hybridization method compositing cross-linking network of PVA-FT and CD gels in single layer gel(PVA Hyb-CP gel), and PVA Hyb-CP gel showed the excellent friction and wear properties under high contact pressure condition. These results indicated that this hybridization method is effective to improve the friction and wear properties of PVA-hybrid gel for artificial cartilage.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (14 results)

All 2018 2017 2016

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results) Presentation (11 results) (of which Int'l Joint Research: 7 results,  Invited: 4 results)

  • [Journal Article] Importance of Adaptive Multimode Lubrication Mechanism in Natural Synovial Joints2017

    • Author(s)
      T. Murakami, S. Yarimitsu, N. Sakai, K. Nakashima, T. Yamaguchi, Y. Sawae
    • Journal Title

      Tribology International

      Volume: 印刷中 Pages: 306-315

    • DOI

      10.1016/j.triboint.2016.12.052

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Superior lubrication mechanism in poly(vinyl alcohol) hybrid gel as artificial cartilage2017

    • Author(s)
      Murakami Teruo、Yarimitsu Seido、Sakai Nobuo、Nakashima Kazuhiro、Yamaguchi Tetsuo、Sawae Yoshinori、Suzuki Atsushi
    • Journal Title

      Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology

      Volume: 231 Issue: 9 Pages: 1160-1170

    • DOI

      10.1177/1350650117712881

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 関節軟骨の潤滑における予荷重の影響と関節液による潤滑効果2017

    • Author(s)
      鎗光清道,橋本直哉,吉田慎之佑,森下聡,藤江裕道
    • Journal Title

      臨床バイオメカニクス

      Volume: 38 Pages: 235-240

    • NAID

      40021345740

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Presentation] Improvement of Tribological Properties of Poly(Vinyl Alcohol) Hybrid Gel2018

    • Author(s)
      Seido Yarimitsu, Teruo Murakami, Atsushi Suzuki
    • Organizer
      The 10th International Biotribology Forum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of pre-loading on tribological property of natural and artificial articular cartilage2017

    • Author(s)
      Seido Yarimitsu, Naoya Hashimoto, Teruo Murakami, Atsushi Suzuki, Hiromichi Fujie
    • Organizer
      バイオメカニクス研究センター&エレクトロニクス実装学会九州支部合同研究会
    • Place of Presentation
      九州大学伊都ゲストハウス(福岡県福岡市)
    • Year and Date
      2017-03-04
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Development of Poly(vinyl alcohol) Hybrid Gel as Artificial Articular Cartilage Material2017

    • Author(s)
      Seido Yarimitsu, Saori Sasaki, Teruo Murakami, Atsushi Suzuki
    • Organizer
      Japan-Korea International Symposium on Material Science and Technology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Influence of Dehydration by Pre-loading on Tribological Property of Hydrogel Artificial Cartilage and Articular Cartilage2017

    • Author(s)
      Seido Yarimitsu, Naoya Hashimoto, Teruo Murakami, Atsushi Suzuki, Hiromichi Fujie
    • Organizer
      6th World Tribology Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Superior Tribological Properties of Poly(Vinyl Alcohol) Hybrid Gel as Artificial Articular Cartilage2017

    • Author(s)
      Seido Yarimitsu, Naoya Hashimoto, Teruo Murakami, Atsushi Suzuki, Hiromichi Fujie
    • Organizer
      Biosurface and Biotribology Chengdu 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of Surface Morphology on Tribological Properties of Poly(vinyl alcohol) Cast-Drying Gel2017

    • Author(s)
      Seido Yarimitsu, Teruo Murakami, Atsushi Suzuki
    • Organizer
      Japan-Taiwan International Tribology Symposium 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 人工関節軟骨候補材料ポリビニルアルコールハイブリッドゲルの低摩耗化2017

    • Author(s)
      鎗光清道,村上輝夫,鈴木淳史
    • Organizer
      トライボロジー会議2017 秋 高松
    • Related Report
      2017 Annual Research Report
  • [Presentation] 予荷重条件がハイドロゲル人工軟骨および生体軟骨の潤滑特性に及ぼす影響2016

    • Author(s)
      鎗光清道,橋本直哉,村上輝夫,鈴木淳史,藤江裕道
    • Organizer
      トライボロジー会議2016 秋 新潟
    • Place of Presentation
      朱鷺メッセ新潟コンベンションセンター(新潟県新潟市)
    • Year and Date
      2016-10-12
    • Related Report
      2016 Research-status Report
  • [Presentation] 関節軟骨の潤滑における予荷重の影響と関節液による潤滑効果2016

    • Author(s)
      鎗光清道,橋本直哉,吉田慎之佑,森下聡,藤江裕道
    • Organizer
      第43回日本臨床バイオメカニクス学会
    • Place of Presentation
      かでる2・7(北海道札幌市)
    • Year and Date
      2016-10-08
    • Related Report
      2016 Research-status Report
  • [Presentation] Influence of preloading on lubrication property of biphasic artificial hydrogel cartilage2016

    • Author(s)
      Seido Yarimitsu, Naoya Hashimoto, Teruo Murakami, Atsushi Suzuki, Hiromichi Fujie
    • Organizer
      3rd International Conference on BioTribology
    • Place of Presentation
      London (United Kingdom)
    • Year and Date
      2016-09-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of Hydrogel Artificial Cartilage Materials for Joint Prosthesis2016

    • Author(s)
      Seido Yarimitsu, Saori Sasaki, Teruo Murakami, Atsushi Suzuki
    • Organizer
      APA 2017 International Conference on Advanced Polymers, Biomaterials, Bioengineering & Nano Drug Delivery
    • Place of Presentation
      Flic En Flac (Mauritius)
    • Year and Date
      2016-09-05
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited

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Published: 2016-04-21   Modified: 2019-03-29  

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