On-Chip Cell Impedance Evaluator
| Project/Area Number |
16K18051
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Osaka University |
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Principal Investigator |
蔡 佳宏 大阪大学, 工学研究科, 特任講師(常勤) (20647490)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Discontinued (Fiscal Year 2016)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | cell impedance / cell manipulation / microfluidics / mechatronics / impedance evaluation / cell viscoelasticity |
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| Outline of Annual Research Achievements |
On-chip cell impedance evaluator has been developed and applied on cell tests. We found clear relations between cell transit speed and deformation from human red blood cells among different subjects. Such relations support the proposed model and it shows that a largely deformed cell would slowly move inside a narrow channel. Single cell impedance may be determined based on such a speed change.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The experimental system has been developed as planned in the proposal. The preliminary results of this work have been published in 5 journal papers and more than 10 conference presentations.
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| Strategy for Future Research Activity |
The schedule for the second year will be focused on cell evaluation with new and different manipulation patterns for determining cycle-dependent viscoelastic characteristics of cells.
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| Expenditure Plan for Carryover Budget |
The incurring amount will be used together with the amount in the 2nd fiscal year.
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Report
(1 results)
Research Products
(15 results)
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[Presentation] On-Chip Cell Gym2017
Author(s)
M. Horade
Organizer
The 30th IEEE Conference on Micro Electro Mechanical Systems (MEMS2017)
Place of Presentation
Rio Las Vegas Hotel and Casino, USA
Year and Date
2017-01-22
Related Report
Int'l Joint Research
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[Presentation] Cell Sweeper for Microfluidic Cavity2016
Author(s)
M. Kaneko
Organizer
The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS16)
Place of Presentation
Convention Center Dublin, Ireland
Year and Date
2016-10-09
Related Report
Int'l Joint Research
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