Project/Area Number |
16K18112
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Measurement engineering
|
Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
TOMA Koji 東京医科歯科大学, 生体材料工学研究所, 助教 (40732269)
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | プラズモン / 心筋梗塞 / モニタリング / 免疫センサ / バイオセンサ / 連続測定 |
Outline of Final Research Achievements |
The purpose of this research was to develop an optical biosensor that can be used for perioperative monitoring of cardiac marker to prevent postoperative acute myocardial infarction. In fiscal year 2016, an optical biosensor for repeated measurement was developed, and it was characterized by a model experiment. In fiscal year 2017 year, along with optimizing and tuning the development of the setup and the system, characterization with a model sample, mouse and anti-mouse antibodies, were continued. It showed increase of the sensor output depending on concentration of anti-mouse antibody along with high reproducibility in a repeated measurement of the antibody.
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