| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Outline of Final Research Achievements |
Understanding how the variation at the genetic level is related to the variation at the phenotypic level is one of the most fundamental goals in biology. Here, we obtained the genome-wide SNP (single-nucleotide polymorphism) data of several hundred horses and performed various population genomic analyses. We identified several regions likely to have been targeted by artificial selection during the domestication process of horses. We also found that the genome of modern Thoroughbred horses has a much higher level of homozygosity due to inbreeding due to the past selective breeding processes of horses. In addition, we proposed an evolutionary model to explain how repetitive sequences contribute to the rewiring of complex regulatory networks during evolution
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